STRINGSTRING
A0A1L9TZ70 A0A1L9TZ70 A0A1L9TD59 A0A1L9TD59 TRM8 TRM8 A0A1L9TEE8 A0A1L9TEE8 A0A1L9TEM2 A0A1L9TEM2 A0A1L9TC28 A0A1L9TC28 A0A1L9TBU2 A0A1L9TBU2 EFM4 EFM4 A0A1L9TB88 A0A1L9TB88 A0A1L9TAG5 A0A1L9TAG5 A0A1L9TAE3 A0A1L9TAE3 A0A1L9T969 A0A1L9T969 A0A1L9T928 A0A1L9T928 A0A1L9T8R0 A0A1L9T8R0 A0A1L9T8C3 A0A1L9T8C3 A0A1L9T7B8 A0A1L9T7B8 A0A1L9T760 A0A1L9T760 A0A1L9T6Z3 A0A1L9T6Z3 A0A1L9T6P8 A0A1L9T6P8 A0A1L9T680 A0A1L9T680 A0A1L9T5K7 A0A1L9T5K7 A0A1L9T2Y8 A0A1L9T2Y8 A0A1L9T2C2 A0A1L9T2C2 EFM6 EFM6 A0A1L9T0R2 A0A1L9T0R2 A0A1L9T082 A0A1L9T082 A0A1L9SZ96 A0A1L9SZ96 A0A1L9SZ89 A0A1L9SZ89 A0A1L9SXX6 A0A1L9SXX6 A0A1L9TFC1 A0A1L9TFC1 A0A1L9TZA9 A0A1L9TZA9 A0A1L9TD08 A0A1L9TD08 A0A1L9TGB6 A0A1L9TGB6 A0A1L9THI7 A0A1L9THI7 A0A1L9THN8 A0A1L9THN8 A0A1L9THT1 A0A1L9THT1 A0A1L9TIT6 A0A1L9TIT6 A0A1L9TKL2 A0A1L9TKL2 A0A1L9TKV4 A0A1L9TKV4 EFM7 EFM7 A0A1L9TMN0 A0A1L9TMN0 A0A1L9TMW5 A0A1L9TMW5 TRM5 TRM5 A0A1L9TNX4 A0A1L9TNX4 A0A1L9TPE9 A0A1L9TPE9 A0A1L9TPH2 A0A1L9TPH2 A0A1L9TQ68 A0A1L9TQ68 A0A1L9TQH6 A0A1L9TQH6 A0A1L9TRA5 A0A1L9TRA5 SPB1 SPB1 A0A1L9TRH0 A0A1L9TRH0 A0A1L9TRH9 A0A1L9TRH9 A0A1L9TRM5 A0A1L9TRM5 A0A1L9TSL0 A0A1L9TSL0 A0A1L9TSY9 A0A1L9TSY9 A0A1L9TT34 A0A1L9TT34 A0A1L9TT98 A0A1L9TT98 A0A1L9TTS9 A0A1L9TTS9 A0A1L9TTU9 A0A1L9TTU9 A0A1L9TTZ1 A0A1L9TTZ1 A0A1L9TU09 A0A1L9TU09 A0A1L9TV20 A0A1L9TV20 A0A1L9TVU3 A0A1L9TVU3 A0A1L9TW03 A0A1L9TW03 A0A1L9TW45 A0A1L9TW45 A0A1L9TXD6 A0A1L9TXD6 COQ5 COQ5 COQ3 COQ3 A0A1L9TYL4 A0A1L9TYL4 A0A1L9TZ38 A0A1L9TZ38 A0A1L9TZ55 A0A1L9TZ55 A0A1L9TZD6 A0A1L9TZD6 A0A1L9TZH4 A0A1L9TZH4 A0A1L9TZI7 A0A1L9TZI7 A0A1L9U028 A0A1L9U028 A0A1L9U113 A0A1L9U113
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1L9TZ70Methyltransf_2 domain-containing protein. (421 aa)
A0A1L9TD59Methyltransf_2 domain-containing protein. (425 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (351 aa)
A0A1L9TEE8FtsJ domain-containing protein. (315 aa)
A0A1L9TEM2Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (349 aa)
A0A1L9TC28Methyltransf_2 domain-containing protein. (410 aa)
A0A1L9TBU2Methyltransf_2 domain-containing protein. (411 aa)
EFM4Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family. (358 aa)
A0A1L9TB88SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (775 aa)
A0A1L9TAG5Methyltransf_2 domain-containing protein. (433 aa)
A0A1L9TAE32-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (567 aa)
A0A1L9T969Uncharacterized protein. (393 aa)
A0A1L9T928Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. (408 aa)
A0A1L9T8R0Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (595 aa)
A0A1L9T8C3Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (377 aa)
A0A1L9T7B825S rRNA adenine-N(1) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA; Belongs to the BMT2 family. (290 aa)
A0A1L9T760Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (969 aa)
A0A1L9T6Z3Methyltransf_2 domain-containing protein. (428 aa)
A0A1L9T6P8U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; Belongs to the methyltransferase superfamily. METTL16/RlmF family. (427 aa)
A0A1L9T680Methyltransf_2 domain-containing protein. (375 aa)
A0A1L9T5K7Methyltransf_2 domain-containing protein. (432 aa)
A0A1L9T2Y8Methyltransf_2 domain-containing protein. (401 aa)
A0A1L9T2C2Methyltransf_2 domain-containing protein. (465 aa)
EFM6Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily. (243 aa)
A0A1L9T0R2Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (714 aa)
A0A1L9T082Methyltransf_2 domain-containing protein. (368 aa)
A0A1L9SZ96Methyltransf_2 domain-containing protein. (404 aa)
A0A1L9SZ89Methyltransf_2 domain-containing protein. (404 aa)
A0A1L9SXX6Methyltransf_2 domain-containing protein. (430 aa)
A0A1L9TFC1Radical_SAM domain-containing protein. (377 aa)
A0A1L9TZA9Methyltransf_2 domain-containing protein. (429 aa)
A0A1L9TD08Methyltransf_2 domain-containing protein. (465 aa)
A0A1L9TGB6Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (500 aa)
A0A1L9THI7SET domain-containing protein; Belongs to the type-B carboxylesterase/lipase family. (1112 aa)
A0A1L9THN82-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (432 aa)
A0A1L9THT1Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (277 aa)
A0A1L9TIT6Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1217 aa)
A0A1L9TKL2Methyltransf_2 domain-containing protein. (423 aa)
A0A1L9TKV4Methyltransf_2 domain-containing protein. (353 aa)
EFM7Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family. (274 aa)
A0A1L9TMN0Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (544 aa)
A0A1L9TMW5rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (638 aa)
TRM5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (1800 aa)
A0A1L9TNX4Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (355 aa)
A0A1L9TPE9Uncharacterized protein. (823 aa)
A0A1L9TPH2Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (415 aa)
A0A1L9TQ68rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (406 aa)
A0A1L9TQH6Protein-L-isoaspartate O-methyltransferase. (241 aa)
A0A1L9TRA5Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (503 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (804 aa)
A0A1L9TRH0tRNA wybutosine-synthesizing protein 2; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. (442 aa)
A0A1L9TRH9TRAM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (543 aa)
A0A1L9TRM5Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (851 aa)
A0A1L9TSL0Methyltransf_2 domain-containing protein. (405 aa)
A0A1L9TSY9Methyltransf_2 domain-containing protein. (396 aa)
A0A1L9TT34Methyltransf_2 domain-containing protein. (438 aa)
A0A1L9TT98SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (574 aa)
A0A1L9TTS9Methyltransf_2 domain-containing protein. (410 aa)
A0A1L9TTU9SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (880 aa)
A0A1L9TTZ1TP_methylase domain-containing protein. (285 aa)
A0A1L9TU09Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (391 aa)
A0A1L9TV20Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC). (202 aa)
A0A1L9TVU3Uncharacterized protein. (242 aa)
A0A1L9TW03Methyltransf_2 domain-containing protein. (385 aa)
A0A1L9TW45Uncharacterized protein. (466 aa)
A0A1L9TXD6Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (430 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (314 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (347 aa)
A0A1L9TYL4Methyltransf_2 domain-containing protein. (294 aa)
A0A1L9TZ38Methyltransf_2 domain-containing protein. (401 aa)
A0A1L9TZ55Methyltransf_2 domain-containing protein. (399 aa)
A0A1L9TZD6Methyltransf_2 domain-containing protein. (419 aa)
A0A1L9TZH4Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (235 aa)
A0A1L9TZI7Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (575 aa)
A0A1L9U028Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family. (969 aa)
A0A1L9U113Methyltransf_2 domain-containing protein. (445 aa)
Your Current Organism:
Aspergillus sydowii
NCBI taxonomy Id: 1036612
Other names: A. sydowii CBS 593.65, Aspergillus sydowii CBS 593.65
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.