(116 nodes) SUMO E3 ligases SUMOylate target proteins network (Aspergillus sydowii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L9SZN9	ADH_N domain-containing protein. (238 aa)
	A0A1L9SZV4	Uncharacterized protein. (678 aa)
	A0A1L9T076	PKS_ER domain-containing protein. (330 aa)
	A0A1L9T0E9	RING-type domain-containing protein. (333 aa)
	A0A1L9T0P5	Uncharacterized protein. (404 aa)
	A0A1L9T0Q3	Uncharacterized protein. (1266 aa)
	A0A1L9T114	Uncharacterized protein. (235 aa)
	A0A1L9U0Q2	PKS_ER domain-containing protein. (359 aa)
	A0A1L9U023	SCD domain-containing protein. (1208 aa)
	A0A1L9U016	Uncharacterized protein. (458 aa)
	A0A1L9TZJ8	PKS_ER domain-containing protein. (326 aa)
	A0A1L9T134	Uncharacterized protein. (595 aa)
	A0A1L9T158	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
	A0A1L9T3U6	Chromatin modification-related protein. (416 aa)
	A0A1L9T307	PKS_ER domain-containing protein. (354 aa)
	A0A1L9T3Z6	PKS_ER domain-containing protein. (939 aa)
	A0A1L9T456	PKS_ER domain-containing protein. (358 aa)
	A0A1L9T4M4	PKS_ER domain-containing protein. (326 aa)
	A0A1L9T4N1	PKS_ER domain-containing protein. (341 aa)
	A0A1L9T5M4	Uncharacterized protein. (266 aa)
	A0A1L9T6L3	Uncharacterized protein. (1357 aa)
	A0A1L9T6X5	Uncharacterized protein. (251 aa)
	A0A1L9T7A8	Fork-head domain-containing protein. (717 aa)
	A0A1L9T7C5	Uncharacterized protein. (584 aa)
	A0A1L9T7G8	Uncharacterized protein. (470 aa)
	A0A1L9T7H9	PKS_ER domain-containing protein. (346 aa)
	A0A1L9T7N1	PKS_ER domain-containing protein. (362 aa)
	A0A1L9T7P2	Uncharacterized protein. (443 aa)
	A0A1L9T7S4	Uncharacterized protein. (354 aa)
	A0A1L9T8E3	Protein kinase domain-containing protein. (892 aa)
	A0A1L9T8P7	Uncharacterized protein. (1054 aa)
	A0A1L9T954	Uncharacterized protein. (319 aa)
	A0A1L9T9C7	SMC_N domain-containing protein. (1195 aa)
	A0A1L9T9M9	PKS_ER domain-containing protein. (332 aa)
	A0A1L9TA36	Uncharacterized protein. (355 aa)
	A0A1L9TAD9	Uncharacterized protein. (416 aa)
	A0A1L9TB39	ANK_REP_REGION domain-containing protein. (1136 aa)
	A0A1L9TBE6	PKS_ER domain-containing protein. (339 aa)
	A0A1L9TC40	C3H1-type domain-containing protein. (523 aa)
	A0A1L9TCA1	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (442 aa)
	A0A1L9TD49	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1717 aa)
	A0A1L9TD73	PKS_ER domain-containing protein. (339 aa)
	A0A1L9TDV1	Uncharacterized protein. (296 aa)
	A0A1L9TE35	MAGE domain-containing protein. (343 aa)
	A0A1L9TEA4	Uncharacterized protein. (594 aa)
	A0A1L9TED8	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (603 aa)
	A0A1L9TEI8	Uncharacterized protein. (591 aa)
	A0A1L9TFV2	Uncharacterized protein. (512 aa)
	A0A1L9TGD4	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (379 aa)
	A0A1L9TGG7	PKS_ER domain-containing protein. (351 aa)
	A0A1L9TGJ6	Uncharacterized protein; Belongs to the DEAD box helicase family. (551 aa)
	A0A1L9THC7	Uncharacterized protein. (870 aa)
	A0A1L9THG6	Uncharacterized protein. (886 aa)
	A0A1L9TIK1	Structural maintenance of chromosomes protein. (1201 aa)
	A0A1L9TIR3	Uncharacterized protein. (219 aa)
	A0A1L9TJ77	Uncharacterized protein. (332 aa)
	A0A1L9TJ78	Peptidase S59 domain-containing protein. (1362 aa)
	A0A1L9TJ86	Uncharacterized protein. (252 aa)
	A0A1L9TJD5	Chromatin modification-related protein. (632 aa)
	A0A1L9TJV6	UDG domain-containing protein. (358 aa)
	A0A1L9TK20	RanBD1 domain-containing protein. (1347 aa)
	A0A1L9TKC2	PKS_ER domain-containing protein. (367 aa)
	A0A1L9TKN3	Uncharacterized protein. (950 aa)
	A0A1L9TLQ7	PKS_ER domain-containing protein. (356 aa)
	A0A1L9TMB8	Uncharacterized protein. (259 aa)
	A0A1L9TMP9	Nop domain-containing protein. (582 aa)
	A0A1L9TMQ7	RRM domain-containing protein. (665 aa)
	A0A1L9TMR9	PKS_ER domain-containing protein. (361 aa)
	A0A1L9TN00	Uncharacterized protein. (301 aa)
	A0A1L9TN12	Structural maintenance of chromosomes protein. (1261 aa)
	A0A1L9TNA1	Chromatin modification-related protein. (695 aa)
	A0A1L9TND8	Uncharacterized protein. (360 aa)
	A0A1L9TZ08	Uncharacterized protein. (1470 aa)
	A0A1L9TNS6	Uncharacterized protein. (707 aa)
	A0A1L9TP21	Uncharacterized protein. (417 aa)
	A0A1L9TP33	Uncharacterized protein. (326 aa)
	A0A1L9TPP1	Uncharacterized protein. (712 aa)
	A0A1L9TQF0	SMC_N domain-containing protein. (1146 aa)
	A0A1L9TQN0	Uncharacterized protein. (953 aa)
	A0A1L9TR67	PKS_ER domain-containing protein. (362 aa)
	A0A1L9TR94	RanBD1 domain-containing protein. (248 aa)
	A0A1L9TRC1	Uncharacterized protein. (839 aa)
	A0A1L9TRT5	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (878 aa)
	A0A1L9TRU1	PKS_ER domain-containing protein. (350 aa)
	A0A1L9TSG5	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (278 aa)
	A0A1L9TSN6	Vezatin domain-containing protein. (616 aa)
	A0A1L9TT92	Uncharacterized protein. (450 aa)
	A0A1L9TTP8	Nup188_C domain-containing protein. (1818 aa)
	A0A1L9TTX1	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (89 aa)
	A0A1L9TV19	WD_REPEATS_REGION domain-containing protein. (362 aa)
	A0A1L9TVC5	BHLH domain-containing protein. (517 aa)
	A0A1L9TVI8	Uncharacterized protein. (1316 aa)
	A0A1L9TVJ0	Uncharacterized protein. (708 aa)
	A0A1L9TVL9	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (1044 aa)
	A0A1L9TVP9	Ubiquitin-like domain-containing protein. (92 aa)
	A0A1L9TW34	Nup54 domain-containing protein. (327 aa)
	A0A1L9TYI5	PKS_ER domain-containing protein. (357 aa)
	A0A1L9TYK2	Uncharacterized protein. (1546 aa)
	A0A1L9TYV1	Uncharacterized protein. (610 aa)
	A0A1L9TYY3	Uncharacterized protein. (477 aa)
	A0A1L9TYZ9	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	A0A1L9T1A7	Hist_deacetyl domain-containing protein. (688 aa)
	A0A1L9T1E0	Uncharacterized protein. (653 aa)
	A0A1L9T1F8	SP-RING-type domain-containing protein. (308 aa)
	A0A1L9T1N3	Nsp1_C domain-containing protein. (660 aa)
	A0A1L9T1X4	Uncharacterized protein. (229 aa)
	A0A1L9T2A3	Uncharacterized protein. (370 aa)
	A0A1L9SXA8	Uncharacterized protein. (88 aa)
	A0A1L9SXH6	Helicase C-terminal domain-containing protein. (218 aa)
	A0A1L9SYB6	Uncharacterized protein. (692 aa)
	A0A1L9SYU5	PKS_ER domain-containing protein. (358 aa)
	A0A1L9T2C4	Uncharacterized protein. (375 aa)
	A0A1L9SZ17	Uncharacterized protein. (252 aa)
	A0A1L9SZ72	Uncharacterized protein. (444 aa)
	A0A1L9SZ81	Uncharacterized protein. (141 aa)
	A0A1L9SZK4	Uncharacterized protein. (311 aa)

Your Current Organism:

Aspergillus sydowii

NCBI taxonomy Id: 1036612
Other names: A. sydowii CBS 593.65, Aspergillus sydowii CBS 593.65

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1L9SXA8	A0A1L9SZV4	Uncharacterized protein.	Uncharacterized protein.	0.500
A0A1L9SXA8	A0A1L9T134	Uncharacterized protein.	Uncharacterized protein.	0.910
A0A1L9SXA8	A0A1L9T158	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.776
A0A1L9SXA8	A0A1L9T1F8	Uncharacterized protein.	SP-RING-type domain-containing protein.	0.447
A0A1L9SXA8	A0A1L9T9C7	Uncharacterized protein.	SMC_N domain-containing protein.	0.652
A0A1L9SXA8	A0A1L9TD49	Uncharacterized protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.680
A0A1L9SXA8	A0A1L9TED8	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.943
A0A1L9SXA8	A0A1L9TIK1	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.460
A0A1L9SXA8	A0A1L9TN00	Uncharacterized protein.	Uncharacterized protein.	0.415
A0A1L9SXA8	A0A1L9TN12	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.415
A0A1L9SXA8	A0A1L9TQF0	Uncharacterized protein.	SMC_N domain-containing protein.	0.683
A0A1L9SXA8	A0A1L9TRT5	Uncharacterized protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.698
A0A1L9SXA8	A0A1L9TSG5	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.703
A0A1L9SXA8	A0A1L9TSN6	Uncharacterized protein.	Vezatin domain-containing protein.	0.703
A0A1L9SXA8	A0A1L9TVP9	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.813
A0A1L9SXH6	A0A1L9SZV4	Helicase C-terminal domain-containing protein.	Uncharacterized protein.	0.500
A0A1L9SXH6	A0A1L9T134	Helicase C-terminal domain-containing protein.	Uncharacterized protein.	0.910
A0A1L9SXH6	A0A1L9T158	Helicase C-terminal domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.776
A0A1L9SXH6	A0A1L9T1F8	Helicase C-terminal domain-containing protein.	SP-RING-type domain-containing protein.	0.447
A0A1L9SXH6	A0A1L9T9C7	Helicase C-terminal domain-containing protein.	SMC_N domain-containing protein.	0.652