STRINGSTRING
murF murF alr0075 alr0075 all0085 all0085 mreC mreC mreB mreB all0089 all0089 asl0090 asl0090 alr0092 alr0092 alr0093 alr0093 asr0098 asr0098 alr0099 alr0099 asr0100 asr0100 alr0101 alr0101 asr0102 asr0102 asr0104 asr0104 asr0105 asr0105 ftsW ftsW all0174 all0174 all0185 all0185 all0187 all0187 all0231 all0231 alr0255 alr0255 alr0477 alr0477 alr0487 alr0487 all0571 all0571 asl0572 asl0572 cphA cphA alr0598 alr0598 alr0653 alr0653 alr0718 alr0718 alr0834 alr0834 all0980 all0980 all0997 all0997 all1140 all1140 alr1167 alr1167 alr1540 alr1540 alr1604 alr1604 alr1605 alr1605 all1663 all1663 alr1690 alr1690 ftsE ftsE all1757 all1757 alr1779 alr1779 all1862 all1862 all1895 all1895 alr1900 alr1900 asl2061 asl2061 all2158 all2158 alr2169 alr2169 alr2269 alr2269 alr2270 alr2270 alr2272 alr2272 lpxB lpxB alr2298 alr2298 alr2304 alr2304 all2320 all2320 alr2338 alr2338 alr2355 alr2355 nlpD nlpD fraC fraC alr2393 alr2393 alr2394 alr2394 alr2458 alr2458 alr2479 alr2479 all2497 all2497 all2506 all2506 alr2717 alr2717 alr2718 alr2718 alr2745 alr2745 rbpE rbpE alr2784 alr2784 all2952 all2952 alr2975 alr2975 all2981 all2981 alr2998 alr2998 alr3074 alr3074 all3310 all3310 alr3353 alr3353 all3420 all3420 c c all3550 all3550 all3585 all3585 alr3608 alr3608 alr3663 alr3663 asl3784 asl3784 asr3830 asr3830 alr3857 alr3857 ftsZ ftsZ all3861 all3861 cphA-2 cphA-2 cphB cphB alr3917 alr3917 alr3921 alr3921 all3922 all3922 alr3930 alr3930 all3971 all3971 all3983 all3983 alr4005 alr4005 alr4007 alr4007 alr4068 alr4068 alr4069 alr4069 alr4112 alr4112 alr4147 alr4147 all4294 all4294 all4316 all4316 alr4332 alr4332 all4350 all4350 all4371 all4371 asl4372 asl4372 alr4393 alr4393 alr4394 alr4394 all4422 all4422 all4499 all4499 alr4509 alr4509 alr4550 alr4550 alr4577 alr4577 alr4579 alr4579 all4699 all4699 alr4701 alr4701 alr4714 alr4714 alr4741 alr4741 asl4743 asl4743 alr4769 alr4769 alr4807 alr4807 patN patN all4829 all4829 all4892 all4892 alr4893 alr4893 alr4984 alr4984 alr5045 alr5045 alr5051 alr5051 alr5065 alr5065 alr5066 alr5066 asl5072 asl5072 all5073 all5073 pbpB pbpB all5163 all5163 alr5164 alr5164 alr5168 alr5168 alr5257 alr5257 all5316 all5316 alr5324 alr5324 alr5326 alr5326 alr5329 alr5329 alr5333 alr5333
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (451 aa)
alr0075ORF_ID:alr0075; hypothetical protein. (491 aa)
all0085ORF_ID:all0085; unknown protein. (170 aa)
mreCRod shape-determining protein; ORF_ID:all0086; mreC gene product. (273 aa)
mreBRod shape-determining protein; ORF_ID:all0087; mreB gene product. (347 aa)
all0089ORF_ID:all0089; hypothetical protein. (221 aa)
asl0090ORF_ID:asl0090; unknown protein. (56 aa)
alr0092N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092. (627 aa)
alr0093N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0093. (627 aa)
asr0098ORF_ID:asr0098; unknown protein. (54 aa)
alr0099ORF_ID:alr0099; unknown protein. (326 aa)
asr0100ORF_ID:asr0100; unknown protein. (58 aa)
alr0101ORF_ID:alr0101; unknown protein. (258 aa)
asr0102ORF_ID:asr0102; unknown protein. (52 aa)
asr0104ORF_ID:asr0104; unknown protein. (50 aa)
asr0105ORF_ID:asr0105; hypothetical protein; Belongs to the RemA family. (88 aa)
ftsWCell division protein; ORF_ID:all0154; ftsW gene product; Belongs to the SEDS family. (396 aa)
all0174UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (447 aa)
all0185Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (554 aa)
all0187Transcriptional regulator; ORF_ID:all0187. (503 aa)
all0231ORF_ID:all0231; hypothetical protein. (385 aa)
alr0255ORF_ID:alr0255; unknown protein. (491 aa)
alr0477phospho-N-acetylmuramoyl-pentapeptide- transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (261 aa)
alr0487Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (198 aa)
all0571Cyanophycinase; Exopeptidase that catalyzes the hydrolytic cleavage of multi- L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. (293 aa)
asl0572ORF_ID:asl0572; unknown protein. (75 aa)
cphACyanophycin synthetase; ORF_ID:alr0573; cphA gene product. (636 aa)
alr0598ORF_ID:alr0598; unknown protein. (231 aa)
alr0653Peptidoglycan glycosyltransferase RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (438 aa)
alr0718Penicillin-binding protein; ORF_ID:alr0718. (609 aa)
alr0834Porin; ORF_ID:alr0834; Belongs to the OprB family. (511 aa)
all0980D-alanyl-D-alanine ligase; Cell wall formation. (364 aa)
all0997ORF_ID:all0997; unknown protein. (136 aa)
all1140ORF_ID:all1140; similar to N-acetylmuramoyl-L-alanine amidase. (313 aa)
alr1167Lysin; ORF_ID:alr1167. (242 aa)
alr1540ORF_ID:alr1540; similar to penicillin-resistant DD-carboxypeptidase. (128 aa)
alr1604ORF_ID:alr1604; hypothetical protein. (247 aa)
alr1605ORF_ID:alr1605; similar to sporulation protein SpoIID. (384 aa)
all1663UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
alr1690Cell wall-binding protein; ORF_ID:alr1690. (424 aa)
ftsECell-division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division. (218 aa)
all1757Cell-division protein; ORF_ID:all1757; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (300 aa)
alr1779ORF_ID:alr1779; similar to cyanophycin synthetase. (333 aa)
all1862ORF_ID:all1862; similar to peptidase. (333 aa)
all1895ORF_ID:all1895; probable glycosyl transferase. (360 aa)
alr1900Phosphoglucomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (494 aa)
asl2061ORF_ID:asl2061; hypothetical protein. (92 aa)
all2158Ferrichrome-iron receptor; ORF_ID:all2158. (878 aa)
alr2169ORF_ID:alr2169; similar to DD-carboxypeptidase. (160 aa)
alr2269ORF_ID:alr2269; chloroplastic outer envelope membrane protein homolog. (833 aa)
alr2270UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (280 aa)
alr2272acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine o-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (252 aa)
lpxBLipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (384 aa)
alr2298Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (456 aa)
alr2304Signal peptidase I; ORF_ID:alr2304; Belongs to the peptidase S26 family. (215 aa)
all2320ORF_ID:all2320; unknown protein. (197 aa)
alr2338ORF_ID:alr2338; hypothetical protein. (751 aa)
alr2355Alanine dehydrogenase; ORF_ID:alr2355; Belongs to the AlaDH/PNT family. (363 aa)
nlpDLipoprotein; ORF_ID:asl2362; nlpD gene product. (77 aa)
fraCFilament integrity protein; Involved in filament integrity. Required for the integrity of cell junctions in general but is apparently not directly involved in normal differentiation and nitrogen fixation. (179 aa)
alr2393ORF_ID:alr2393; unknown protein. (343 aa)
alr2394ORF_ID:alr2394; hypothetical protein. (267 aa)
alr2458Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (401 aa)
alr2479Transcriptional regulator; ORF_ID:alr2479. (476 aa)
all2497UDP-N-acetyl glucosamine-2-epimerase; ORF_ID:all2497; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (370 aa)
all2506Cyanophycinase; Exopeptidase that catalyzes the hydrolytic cleavage of multi- L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. (323 aa)
alr2717ORF_ID:alr2717; hypothetical protein. (447 aa)
alr2718ORF_ID:alr2718; probable cobyric acid synthase. (273 aa)
alr2745ORF_ID:alr2745; hypothetical protein. (305 aa)
rbpERNA binding protein; ORF_ID:all2777; rbpE gene product. (99 aa)
alr2784ORF_ID:alr2784; hypothetical protein. (840 aa)
all2952Penicillin-binding protein; ORF_ID:all2952. (755 aa)
alr2975ORF_ID:alr2975; signal peptidase I; Belongs to the peptidase S26 family. (190 aa)
all2981Penicillin-binding protein; ORF_ID:all2981. (640 aa)
alr2998Ribosomal-protein-alanine acetyltransferase; ORF_ID:alr2998. (182 aa)
alr3074UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (349 aa)
all3310ORF_ID:all3310; hypothetical protein. (698 aa)
alr3353ORF_ID:alr3353; putative peptidase. (760 aa)
all3420Carboxyl-terminal processing protease; ORF_ID:all3420; Belongs to the peptidase S41A family. (417 aa)
cC protein; ORF_ID:all3549; similar to phycoerythrobilin lyase subunit (cpeF). (159 aa)
all3550ORF_ID:all3550; similar to spore cortex-lytic enzyme prepeptide. (208 aa)
all3585ORF_ID:all3585; unknown protein. (278 aa)
alr3608ORF_ID:alr3608; similar to endoglucanase. (552 aa)
alr3663ORF_ID:alr3663; unknown protein. (349 aa)
asl3784ORF_ID:asl3784; hypothetical protein. (91 aa)
asr3830ORF_ID:asr3830; hypothetical protein. (89 aa)
alr3857ORF_ID:alr3857; hypothetical protein. (281 aa)
ftsZCell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (428 aa)
all3861ORF_ID:all3861; unknown protein. (236 aa)
cphA-2Cyanophycin synthetase; Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer); In the C-terminal section; belongs to the MurCDEF family. (901 aa)
cphBCyanophycinase; Exopeptidase that catalyzes the hydrolytic cleavage of multi- L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. (298 aa)
alr3917ORF_ID:alr3917; unknown protein. (447 aa)
alr3921UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa)
all3922L-asparaginase; Degrades proteins damaged by L-isoaspartyl residue formation (also known as beta-Asp residues). Probably performs the final step in the degradation of the reserve polymer cyanophycin (depolymerizes the building block L-beta-Asp-Arg). Also has L-asparaginase activity. (318 aa)
alr3930ORF_ID:alr3930; unknown protein. (228 aa)
all3971Putative zinc metalloprotease all3971; ORF_ID:all3971; hypothetical protein; Belongs to the peptidase M50B family. (364 aa)
all3983ORF_ID:all3983; similar to surface layer protein. (400 aa)
alr4005ORF_ID:alr4005; hypothetical protein. (418 aa)
alr4007ORF_ID:alr4007; hypothetical protein. (198 aa)
alr4068ATP-binding protein of ABC transporter; ORF_ID:alr4068. (242 aa)
alr4069ORF_ID:alr4069; hypothetical protein. (371 aa)
alr4112UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (462 aa)
alr4147Amidase enhancer; ORF_ID:alr4147. (555 aa)
all4294ORF_ID:all4294; probable N-acetylmuramoyl-L-alanine amidase. (508 aa)
all4316phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (369 aa)
alr4332Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (225 aa)
all4350ORF_ID:all4350; unknown protein. (434 aa)
all4371ORF_ID:all4371; hypothetical protein. (296 aa)
asl4372ORF_ID:asl4372; unknown protein. (78 aa)
alr4393ORF_ID:alr4393; hypothetical protein. (496 aa)
alr4394Putative pre-16S rRNA nuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (148 aa)
all4422UDP-N-acetyl-D-mannosamine transferase; ORF_ID:all4422; Belongs to the glycosyltransferase 26 family. (257 aa)
all4499ORF_ID:all4499; hypothetical protein; Belongs to the OprB family. (546 aa)
alr4509ORF_ID:alr4509; hypothetical protein. (349 aa)
alr4550ORF_ID:alr4550; hypothetical protein; Belongs to the OprB family. (575 aa)
alr4577Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (158 aa)
alr4579Penicillin-binding protein; ORF_ID:alr4579. (756 aa)
all4699Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (283 aa)
alr4701ORF_ID:alr4701; hypothetical protein. (147 aa)
alr4714ORF_ID:alr4714; unknown protein. (232 aa)
alr4741ORF_ID:alr4741; hypothetical protein; Belongs to the OprB family. (555 aa)
asl4743ORF_ID:asl4743; unknown protein. (63 aa)
alr4769ORF_ID:alr4769; unknown protein. (227 aa)
alr4807ORF_ID:alr4807; probable glycosyltransferase. (348 aa)
patNHeterocyst differentiation related protein; ORF_ID:alr4812; patN gene product. (215 aa)
all4829Undecaprenyl-phosphate galactosephosphotransferase; ORF_ID:all4829. (252 aa)
all4892ORF_ID:all4892; hypothetical protein. (456 aa)
alr4893ORF_ID:alr4893; hypothetical protein. (676 aa)
alr4984ORF_ID:alr4984; unknown protein. (203 aa)
alr5045Penicillin-binding protein; ORF_ID:alr5045. (610 aa)
alr5051ORF_ID:alr5051; hypothetical protein. (191 aa)
alr5065UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation; Belongs to the MurCDEF family. (494 aa)
alr5066UDP-N-acetylenolpyruvylglucosamine reductase; Cell wall formation. (331 aa)
asl5072ORF_ID:asl5072; unknown protein. (53 aa)
all5073ORF_ID:all5073; hypothetical protein. (475 aa)
pbpBPenicillin-binding protein 2; ORF_ID:alr5101. (763 aa)
all5163ORF_ID:all5163; hypothetical protein. (295 aa)
alr5164Serine protease; ORF_ID:alr5164. (401 aa)
alr5168ORF_ID:alr5168; hypothetical protein. (319 aa)
alr5257ORF_ID:alr5257; probable peptidase. (401 aa)
all5316ORF_ID:all5316; unknown protein. (316 aa)
alr5324Penicillin-binding protein; ORF_ID:alr5324. (643 aa)
alr5326Penicillin-binding protein; ORF_ID:alr5326. (643 aa)
alr5329ORF_ID:alr5329; unknown protein. (211 aa)
alr5333ORF_ID:alr5333; unknown protein. (130 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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