STRINGSTRING
murF murF all0085 all0085 mreC mreC mreB mreB alr0092 alr0092 ftsW ftsW all0174 all0174 all0185 all0185 alr0477 alr0477 alr0487 alr0487 alr0653 alr0653 alr0718 alr0718 all0980 all0980 all1663 all1663 ftsE ftsE all1757 all1757 all1862 all1862 alr1900 alr1900 asl2061 asl2061 alr2304 alr2304 nlpD nlpD all2952 all2952 alr2975 alr2975 all2981 all2981 alr2998 alr2998 alr3353 alr3353 all3420 all3420 alr3857 alr3857 ftsZ ftsZ alr3921 alr3921 all3971 all3971 alr4007 alr4007 alr4112 alr4112 all4316 all4316 alr4577 alr4577 alr4579 alr4579 all4699 all4699 alr4701 alr4701 alr5045 alr5045 alr5051 alr5051 alr5065 alr5065 alr5066 alr5066 pbpB pbpB all5163 all5163 alr5164 alr5164 alr5257 alr5257 alr5324 alr5324 alr5326 alr5326
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (451 aa)
all0085ORF_ID:all0085; unknown protein. (170 aa)
mreCRod shape-determining protein; ORF_ID:all0086; mreC gene product. (273 aa)
mreBRod shape-determining protein; ORF_ID:all0087; mreB gene product. (347 aa)
alr0092N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092. (627 aa)
ftsWCell division protein; ORF_ID:all0154; ftsW gene product; Belongs to the SEDS family. (396 aa)
all0174UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (447 aa)
all0185Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (554 aa)
alr0477phospho-N-acetylmuramoyl-pentapeptide- transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (261 aa)
alr0487Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (198 aa)
alr0653Peptidoglycan glycosyltransferase RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (438 aa)
alr0718Penicillin-binding protein; ORF_ID:alr0718. (609 aa)
all0980D-alanyl-D-alanine ligase; Cell wall formation. (364 aa)
all1663UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
ftsECell-division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division. (218 aa)
all1757Cell-division protein; ORF_ID:all1757; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (300 aa)
all1862ORF_ID:all1862; similar to peptidase. (333 aa)
alr1900Phosphoglucomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (494 aa)
asl2061ORF_ID:asl2061; hypothetical protein. (92 aa)
alr2304Signal peptidase I; ORF_ID:alr2304; Belongs to the peptidase S26 family. (215 aa)
nlpDLipoprotein; ORF_ID:asl2362; nlpD gene product. (77 aa)
all2952Penicillin-binding protein; ORF_ID:all2952. (755 aa)
alr2975ORF_ID:alr2975; signal peptidase I; Belongs to the peptidase S26 family. (190 aa)
all2981Penicillin-binding protein; ORF_ID:all2981. (640 aa)
alr2998Ribosomal-protein-alanine acetyltransferase; ORF_ID:alr2998. (182 aa)
alr3353ORF_ID:alr3353; putative peptidase. (760 aa)
all3420Carboxyl-terminal processing protease; ORF_ID:all3420; Belongs to the peptidase S41A family. (417 aa)
alr3857ORF_ID:alr3857; hypothetical protein. (281 aa)
ftsZCell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (428 aa)
alr3921UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa)
all3971Putative zinc metalloprotease all3971; ORF_ID:all3971; hypothetical protein; Belongs to the peptidase M50B family. (364 aa)
alr4007ORF_ID:alr4007; hypothetical protein. (198 aa)
alr4112UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (462 aa)
all4316phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (369 aa)
alr4577Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (158 aa)
alr4579Penicillin-binding protein; ORF_ID:alr4579. (756 aa)
all4699Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (283 aa)
alr4701ORF_ID:alr4701; hypothetical protein. (147 aa)
alr5045Penicillin-binding protein; ORF_ID:alr5045. (610 aa)
alr5051ORF_ID:alr5051; hypothetical protein. (191 aa)
alr5065UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation; Belongs to the MurCDEF family. (494 aa)
alr5066UDP-N-acetylenolpyruvylglucosamine reductase; Cell wall formation. (331 aa)
pbpBPenicillin-binding protein 2; ORF_ID:alr5101. (763 aa)
all5163ORF_ID:all5163; hypothetical protein. (295 aa)
alr5164Serine protease; ORF_ID:alr5164. (401 aa)
alr5257ORF_ID:alr5257; probable peptidase. (401 aa)
alr5324Penicillin-binding protein; ORF_ID:alr5324. (643 aa)
alr5326Penicillin-binding protein; ORF_ID:alr5326. (643 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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