STRINGSTRING
all5206 all5206 all5167 all5167 all5138 all5138 all5063 all5063 all5014 all5014 alr4932 alr4932 all4896 all4896 alr4848 alr4848 all4705 all4705 alr4700 alr4700 asr4648 asr4648 agp agp all4538 all4538 alr4491 alr4491 alr4466 alr4466 all4396 all4396 all4342 all4342 rpoA rpoA all3989 all3989 alr3921 alr3921 all3875 all3875 all3578 all3578 alr3504 alr3504 alr3497 alr3497 alr3444 alr3444 alr3400 alr3400 all3274 all3274 all3174 all3174 all3136 all3136 all2996 all2996 all2961 all2961 all2876 all2876 alr2825 alr2825 all2796 all2796 alr2483 alr2483 alr2361 alr2361 dnaN dnaN rpoC2 rpoC2 rpoC1 rpoC1 rpoB rpoB alr1468 alr1468 all1323 all1323 alr1254 alr1254 alr1160 alr1160 all0961 all0961 cpcG4 cpcG4 cpcG3 cpcG3 cpcG2 cpcG2 cpcG1 cpcG1 alr0188 alr0188 alr0069 alr0069
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
all5206ORF_ID:all5206; probable reverse transcriptase. (539 aa)
all51674-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (228 aa)
all5138Sulfate adenylyltransferase; ORF_ID:all5138; Belongs to the sulfate adenylyltransferase family. (343 aa)
all5063Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (208 aa)
all5014ORF_ID:all5014; hypothetical protein. (282 aa)
alr4932DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (655 aa)
all4896ORF_ID:all4896; hypothetical protein. (516 aa)
alr4848Riboflavin kinase/FAD synthase; ORF_ID:alr4848; Belongs to the ribF family. (362 aa)
all4705All4705 protein; DNA polymerase III, delta prime subunit; ORF_ID:all4705. (320 aa)
alr4700Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (191 aa)
asr4648DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (78 aa)
agpGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. (429 aa)
all4538Mannose-6-phosphate isomerase; ORF_ID:all4538. (135 aa)
alr4491Glucose-1-phosphate thymidylyltransferase; ORF_ID:alr4491. (358 aa)
alr4466Ap4A phosphorylase II; ORF_ID:alr4466. (303 aa)
all4396Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (718 aa)
all4342Mannose-6-phosphate isomerase; ORF_ID:all4342. (140 aa)
rpoARNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (315 aa)
all3989polyA polymerase; ORF_ID:all3989; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (904 aa)
alr3921UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa)
all3875Phosphatidate cytidylyltransferase; ORF_ID:all3875; Belongs to the CDS family. (294 aa)
all3578DNA polymerase III alpha subunit; ORF_ID:all3578. (877 aa)
alr3504ORF_ID:alr3504; unknown protein. (307 aa)
alr3497ORF_ID:alr3497; hypothetical protein. (352 aa)
alr3444ORF_ID:alr3444; hypothetical protein. (329 aa)
alr3400Mannose-1-phosphate guanyltransferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. (389 aa)
all3274UTP-glucose-1-phosphate uridylyltransferase; ORF_ID:all3274. (293 aa)
all3174Cobinamide kinase; ORF_ID:all3174. (181 aa)
all3136polyA polymerase; ORF_ID:all3136. (422 aa)
all2996Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (321 aa)
all2961ORF_ID:all2961; similar to reverse transcriptase. (306 aa)
all2876Protein adenylyltransferase SelO; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). (485 aa)
alr2825glucose-1-P cytidylyltransferase; ORF_ID:alr2825. (257 aa)
all2796ORF_ID:all2796; hypothetical protein. (470 aa)
alr2483Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa)
alr2361Mannose-1-phosphate guanyltransferase; ORF_ID:alr2361. (842 aa)
dnaNDNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (387 aa)
rpoC2RNA polymerase beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily. (1350 aa)
rpoC1RNA polymerase gamma subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (625 aa)
rpoBRNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1131 aa)
alr1468CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (668 aa)
all1323DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (640 aa)
alr1254DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (977 aa)
alr1160ORF_ID:alr1160; hypothetical protein. (100 aa)
all0961Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (207 aa)
cpcG4Phycobilisome rod-core linker protein; Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes. (253 aa)
cpcG3Phycobilisome rod-core linker protein; Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes. (237 aa)
cpcG2Phycobilisome rod-core linker protein; Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes. (247 aa)
cpcG1Phycobilisome rod-core linker protein; Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes. (279 aa)
alr0188GDP-mannose pyrophosphorylase; ORF_ID:alr0188. (358 aa)
alr0069Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (247 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
Server load: low (18%) [HD]