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alr1026 alr1026 all1053 all1053 alr1155 alr1155 alr1396 alr1396 all1663 all1663 alr1779 alr1779 gvpF gvpF purC purC glnA glnA asr2474 asr2474 all2349 all2349 alr3934 alr3934 alr4112 alr4112 all4540 all4540 alr4619 alr4619 all4667 all4667 alr4784 alr4784 argG argG all4825 all4825 alr5000 alr5000 alr5065 alr5065 alr5095 alr5095 alr5256 alr5256 cphA-2 cphA-2 alr3809 alr3809 murF murF all0217 all0217 all0390 all0390 all0394 all0394 cphA cphA all0721 all0721 all0932 all0932 accC accC all0980 all0980 alr1018 alr1018 all3859 all3859 alr2475 alr2475 alr2482 alr2482 alr2485 alr2485 alr2717 alr2717 alr2718 alr2718 alr2742 alr2742 all2846 all2846 panC panC all3111 all3111 asl3192 asl3192 alr3303 alr3303 alr3351 alr3351 alr3510 alr3510 alr3525 alr3525 all3652 all3652
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
alr1026Folylpolyglutamate synthase; ORF_ID:alr1026; Belongs to the folylpolyglutamate synthase family. (417 aa)
all1053glutamyl-tRNA (Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (486 aa)
alr1155Carbamoyl phosphate synthase small subunit; ORF_ID:alr1155; Belongs to the CarA family. (388 aa)
alr1396glutamyl-tRNA (Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (491 aa)
all1663UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
alr1779ORF_ID:alr1779; similar to cyanophycin synthetase. (333 aa)
gvpFGas vesicle protein; ORF_ID:all2248; gvpF gene product. (244 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; ORF_ID:alr2268; purC gene product; Belongs to the SAICAR synthetase family. (245 aa)
glnAGlutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (474 aa)
asr2474Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (92 aa)
all2349ORF_ID:all2349; unknown protein. (538 aa)
alr3934Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (514 aa)
alr4112UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (462 aa)
all4540ORF_ID:all4540; hypothetical protein. (137 aa)
alr4619ORF_ID:alr4619; similar to pathogenesis related protein. (266 aa)
all4667Dethiobiotin synthase; ORF_ID:all4667; hypothetical protein. (187 aa)
alr4784Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (419 aa)
argGArgininosuccinate synthase; ORF_ID:alr4798; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa)
all48255-formyltetrahydrofolate cyclo-ligase; ORF_ID:all4825; hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (193 aa)
alr5000CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
alr5065UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation; Belongs to the MurCDEF family. (494 aa)
alr50957-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (229 aa)
alr5256Biotin acetyl-CoA carboxylase ligase; ORF_ID:alr5256. (274 aa)
cphA-2Cyanophycin synthetase; Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer); In the C-terminal section; belongs to the MurCDEF family. (901 aa)
alr3809Carbamoyl phosphate synthetase large chain; ORF_ID:alr3809. (1104 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (451 aa)
all0217ORF_ID:all0217; similar to pathogenesis related protein. (239 aa)
all0390ORF_ID:all0390; hypothetical protein. (579 aa)
all0394ORF_ID:all0394; hypothetical protein. (606 aa)
cphACyanophycin synthetase; ORF_ID:alr0573; cphA gene product. (636 aa)
all0721ORF_ID:all0721; unknown protein. (372 aa)
all0932tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (342 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
all0980D-alanyl-D-alanine ligase; Cell wall formation. (364 aa)
alr1018Glu-tRNA(Gln) amidotransferase subunit A; ORF_ID:alr1018. (464 aa)
all3859Glutathione synthetase; ORF_ID:all3859. (324 aa)
alr2475Phosphoribosylformyl glycinamidine synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (224 aa)
alr2482Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (459 aa)
alr2485NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (566 aa)
alr2717ORF_ID:alr2717; hypothetical protein. (447 aa)
alr2718ORF_ID:alr2718; probable cobyric acid synthase. (273 aa)
alr2742Phosphoribosyl aminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa)
all2846GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (540 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (534 aa)
all3111Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (410 aa)
asl3192glutamyl-tRNA (Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (96 aa)
alr3303ORF_ID:alr3303; hypothetical protein. (328 aa)
alr3351Glutamate--cysteine ligase; ORF_ID:alr3351; hypothetical protein. (379 aa)
alr3510Phosphoribosylamine--glycine ligase; ORF_ID:alr3510. (425 aa)
alr3525Phosphoribosylformylglycinamidine cyclo-ligase; ORF_ID:alr3525. (425 aa)
all3652Phosphoribosylformyl glycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (782 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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