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| | all0746 | ORF_ID:all0746; hypothetical protein. (159 aa) |
| | alr0725 | ORF_ID:alr0725; hypothetical protein. (148 aa) |
| | all0661 | Adenylate cyclase; ORF_ID:all0661; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (472 aa) |
| | alr0599 | 1-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (635 aa) |
| | alr0515 | Alr0515 protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (240 aa) |
| | alr0512 | ORF_ID:alr0512; hypothetical protein. (268 aa) |
| | all0492 | Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (226 aa) |
| | all0405 | ORF_ID:all0405; hypothetical protein. (692 aa) |
| | alr0386 | ORF_ID:alr0386; hypothetical protein. (444 aa) |
| | all0282 | ORF_ID:all0282; unknown protein. (162 aa) |
| | all0270 | Diacylglycerol kinase; ORF_ID:all0270. (151 aa) |
| | all0251 | ORF_ID:all0251; hypothetical protein. (276 aa) |
| | all0250 | ORF_ID:all0250; hypothetical protein. (275 aa) |
| | alr0241 | ORF_ID:alr0241; putative acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (212 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (341 aa) |
| | alr0234 | ORF_ID:alr0234; unknown protein. (241 aa) |
| | alr0227 | NAD kinase 2; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (306 aa) |
| | alr0212 | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (299 aa) |
| | all0122 | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa) |
| | alr0106 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa) |
| | alr0068 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa) |
| | all0066 | dCTP deaminase; ORF_ID:all0066. (199 aa) |
| | alr0051 | IMP dehydrogenase; ORF_ID:alr0051. (387 aa) |
| | atpI | ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (251 aa) |
| | atpH | ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa) |
| | atpF | ATP synthase subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (187 aa) |
| | atpD | ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (183 aa) |
| | atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit; Belongs to the ATPase alpha/beta chains family. (506 aa) |
| | atpC | ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (315 aa) |
| | alr4784 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (419 aa) |
| | alr4795 | ORF_ID:alr4795; hypothetical protein. (157 aa) |
| | alr4808 | CinA-like protein; ORF_ID:alr4808; competence-damage inducible protein CinA homolog; Belongs to the CinA family. (424 aa) |
| | alr4846 | Stationary phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (265 aa) |
| | alr4848 | Riboflavin kinase/FAD synthase; ORF_ID:alr4848; Belongs to the ribF family. (362 aa) |
| | all4871 | ORF_ID:all4871; hypothetical protein. (287 aa) |
| | alr5000 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | alr5010 | D-hydantoinase; ORF_ID:alr5010. (496 aa) |
| | atpE | ATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (137 aa) |
| | atpB | ATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (482 aa) |
| | all5052 | ORF_ID:all5052; hypothetical protein. (458 aa) |
| | alr5061 | Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (332 aa) |
| | all5063 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (208 aa) |
| | all5088 | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa) |
| | alr5099 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (206 aa) |
| | moeA | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP; Belongs to the MoeA family. (436 aa) |
| | all5167 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (228 aa) |
| | alr5275 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa) |
| | accA | acetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa) |
| | alr5287 | GTP cyclohydrolase I; ORF_ID:alr5287. (235 aa) |
| | atpG | ATP synthase subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (163 aa) |
| | pdxA | Pyridoxal phosphate biosynthetic protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (362 aa) |
| | all4751 | NAD kinase 1; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (305 aa) |
| | all4721 | GTP cyclohydrolase I; ORF_ID:all4721. (216 aa) |
| | all4708 | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa) |
| | alr4700 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (191 aa) |
| | amt1 | Ammonium transporter protein 1; ORF_ID:alr4682; amt1 gene product. (290 aa) |
| | all4673 | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (324 aa) |
| | all4671 | ORF_ID:all4671; hypothetical protein. (193 aa) |
| | alr4670 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (330 aa) |
| | all4665 | ORF_ID:all4665; hypothetical protein. (364 aa) |
| | alr4596 | Malic enzyme; ORF_ID:alr4596. (463 aa) |
| | alr4582 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa) |
| | fda | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa) |
| | alr4466 | Ap4A phosphorylase II; ORF_ID:alr4466. (303 aa) |
| | all4461 | Inositol monophosphate family protein; ORF_ID:all4461. (268 aa) |
| | all4418 | ORF_ID:all4418; unknown protein. (347 aa) |
| | alr4385 | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa) |
| | asl4353 | ORF_ID:asl4353; hypothetical protein. (86 aa) |
| | alr4351 | Deoxyxylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (399 aa) |
| | all4350 | ORF_ID:all4350; unknown protein. (434 aa) |
| | all4349 | ORF_ID:all4349; unknown protein. (399 aa) |
| | all4348 | ORF_ID:all4348; unknown protein. (395 aa) |
| | all4272 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (376 aa) |
| | all4257 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (524 aa) |
| | all4256 | Acetyl-coenzyme A synthetase; ORF_ID:all4256. (132 aa) |
| | alr4223 | Cardiolipin synthase; ORF_ID:alr4223; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (480 aa) |
| | all4196 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa) |
| | all4182 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (533 aa) |
| | alr4174 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (226 aa) |
| | all4131 | Phosphoglycerate kinase; ORF_ID:all4131. (400 aa) |
| | all4063 | Phosphatidylglycerophosphate synthase; ORF_ID:all4063; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (172 aa) |
| | all4052 | Transketolase; ORF_ID:all4052. (633 aa) |
| | alr4036 | ORF_ID:alr4036; hypothetical protein. (194 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (381 aa) |
| | zwf | Glucose 6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (509 aa) |
| | all4008 | Pyruvate kinase; ORF_ID:all4008; Belongs to the pyruvate kinase family. (589 aa) |
| | alr4005 | ORF_ID:alr4005; hypothetical protein. (418 aa) |
| | alr3921 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa) |
| | all3914 | succinyl-CoA synthetase beta chain; ORF_ID:all3914. (408 aa) |
| | alr3896 | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (276 aa) |
| | alr3885 | ORF_ID:alr3885; probable phosphoribosylaminoimidazole carboxylase catalytic subunit. (262 aa) |
| | alr3883 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (165 aa) |
| | all3875 | Phosphatidate cytidylyltransferase; ORF_ID:all3875; Belongs to the CDS family. (294 aa) |
| | all3865 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa) |
| | alr3809 | Carbamoyl phosphate synthetase large chain; ORF_ID:alr3809. (1104 aa) |
| | all3735 | Fructose-bisphosphate aldolase class I; ORF_ID:all3735. (360 aa) |
| | all3704 | ORF_ID:all3704; probable phosphoribosyltransferase. (172 aa) |
| | all3652 | Phosphoribosylformyl glycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (782 aa) |
| | all3651 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (499 aa) |
| | alr3606 | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. (430 aa) |
| | all3538 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa) |
| | alr3533 | ORF_ID:alr3533; hypothetical protein. (184 aa) |
| | alr3525 | Phosphoribosylformylglycinamidine cyclo-ligase; ORF_ID:alr3525. (425 aa) |
| | thiG | Thiamin biosynthesis protein; Catalyzes the FAD-dependent oxidative deamination of glycine. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate; In the N-terminal section; belongs to the DAO family. ThiO subfamily. (652 aa) |
| | alr3510 | Phosphoribosylamine--glycine ligase; ORF_ID:alr3510. (425 aa) |
| | alr3402 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (117 aa) |
| | alr3395 | Adenylosuccinate lyase; ORF_ID:alr3395; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | alr3382 | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (168 aa) |
| | alr3344 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate; Belongs to the transketolase family. (670 aa) |
| | alr3339 | Dihydroorotase; ORF_ID:alr3339. (435 aa) |
| | asr3294 | ORF_ID:asr3294; hypothetical protein. (91 aa) |
| | alr3230 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (317 aa) |
| | all3208 | ORF_ID:all3208; hypothetical protein. (394 aa) |
| | all3160 | ORF_ID:all3160; hypothetical protein. (171 aa) |
| | alr3139 | Putative 5'-nucleotidase alr3139; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (226 aa) |
| | all3111 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (410 aa) |
| | purH | Bifunctional purine biosynthesis protein; ORF_ID:all3093; purH gene product. (506 aa) |
| | all3075 | Nucleoside triphosphate pyrophosphatase; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (197 aa) |
| | alr3074 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (349 aa) |
| | all3029 | ORF_ID:all3029; hypothetical protein. (126 aa) |
| | all2996 | Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (321 aa) |
| | alr2983 | Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (238 aa) |
| | alr2973 | Glucokinase; ORF_ID:alr2973; Belongs to the bacterial glucokinase family. (342 aa) |
| | alr2957 | ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...] (530 aa) |
| | alr2954 | ORF_ID:alr2954; hypothetical protein. (182 aa) |
| | alr2945 | Orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (500 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (534 aa) |
| | all2917 | Inositol monophophatase family; ORF_ID:all2917; Belongs to the inositol monophosphatase superfamily. (270 aa) |
| | alr2881 | ORF_ID:alr2881; hypothetical protein. (315 aa) |
| | all2846 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (540 aa) |
| | alr2742 | Phosphoribosyl aminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) |
| | alr2708 | Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa) |
| | alr2695 | ORF_ID:alr2695; unknown protein. (161 aa) |
| | gap1 | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. (343 aa) |
| | all2564 | Pyruvate kinase; ORF_ID:all2564; Belongs to the pyruvate kinase family. (476 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (332 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa) |
| | all2501 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (408 aa) |
| | alr2485 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (566 aa) |
| | alr2483 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa) |
| | alr2482 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (459 aa) |
| | alr2475 | Phosphoribosylformyl glycinamidine synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (224 aa) |
| | asr2474 | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (92 aa) |
| | accD | acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (316 aa) |
| | alr2350 | Phosphoribulokinase; ORF_ID:alr2350. (313 aa) |
| | all2333 | ORF_ID:all2333; hypothetical protein. (595 aa) |
| | all2303 | Dihydroorotase; ORF_ID:all2303. (439 aa) |
| | lpxB | Lipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (384 aa) |
| | alr2272 | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine o-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (252 aa) |
| | alr2271 | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (171 aa) |
| | alr2270 | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (280 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; ORF_ID:alr2268; purC gene product; Belongs to the SAICAR synthetase family. (245 aa) |
| | cyaB1 | Adenylate cyclase; ORF_ID:alr2266; cyaB1 gene product. (859 aa) |
| | phnG | Phosphonate metabolism protein; ORF_ID:all2225; phnG gene product. (151 aa) |
| | phnH | Phosphonate metabolism protein; ORF_ID:all2224; phnH gene product. (199 aa) |
| | phnI | Phosphonate metabolism protein; ORF_ID:all2222; phnI gene product. (415 aa) |
| | phnM-2 | Phosphonate metabolism protein; ORF_ID:all2221; phnM gene product. (500 aa) |
| | phnJ | Phosphonate metabolism protein; ORF_ID:all2219; phnJ gene product. (288 aa) |
| | phnK | Phosphonate ABC transporter, ATP-binding component; ORF_ID:all2218; phnK gene product. (257 aa) |
| | phnL | Phosphonate ABC transporter, ATP-binding component; ORF_ID:all2217; phnL gene product. (241 aa) |
| | phnM | Phosphonate metabolism protein; ORF_ID:all2216; phnM gene product. (378 aa) |
| | all2091 | Nicotinate-nucleotide pyrophosphorylase; ORF_ID:all2091; Belongs to the NadC/ModD family. (287 aa) |
| | all2063 | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (216 aa) |
| | alr1913 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (357 aa) |
| | alr1912 | Alr1912 protein; Catalyzes the conversion of dihydroorotate to orotate. (343 aa) |
| | all1876 | ORF_ID:all1876; hypothetical protein. (323 aa) |
| | all1811 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (500 aa) |
| | all1754 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (196 aa) |
| | all1693 | Glycerol-3-phosphate dehydrogenase; ORF_ID:all1693; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (307 aa) |
| | all1681 | Aspartate carbamoyltransferase; ORF_ID:all1681; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (333 aa) |
| | moaE | Molybdopterin converting factor, subunit 2; Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family. (165 aa) |
| | alr1623 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa) |
| | devB | glucose-6-P-dehydrogenase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. (240 aa) |
| | all1549 | (p)ppGpp 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (751 aa) |
| | asr1344 | ORF_ID:asr1344; hypothetical protein. (70 aa) |
| | alr1343 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (379 aa) |
| | alr1299 | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (391 aa) |
| | all1248 | Pyridoxamine 5-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa) |
| | alr1233 | ORF_ID:alr1233; hypothetical protein. (276 aa) |
| | all1219 | ORF_ID:all1219; hypothetical protein. (737 aa) |
| | alr1217 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (578 aa) |
| | alr1207 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa) |
| | alr1155 | Carbamoyl phosphate synthase small subunit; ORF_ID:alr1155; Belongs to the CarA family. (388 aa) |
| | cyaA | Adenylate cyclase; ORF_ID:all1118; cyaA gene product. (735 aa) |
| | gap3 | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG; Belongs to the glyceraldehyde-3-phosphate dehydrogenase [...] (337 aa) |
| | alr1050 | Glucose-6-phosphate isomerase; ORF_ID:alr1050. (528 aa) |
| | alr1004 | Alanine--glyoxylate aminotransferase; ORF_ID:alr1004. (381 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (175 aa) |
| | all0985 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (402 aa) |
| | thiC | Thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (457 aa) |
| | alr0981 | ORF_ID:alr0981; hypothetical protein. (282 aa) |
| | all0961 | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (207 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | all0888 | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (236 aa) |
| | all0850 | ORF_ID:all0850; putative acyltransferase. (314 aa) |
| | all0800 | Molybdopterin precursor biosynthesis protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (167 aa) |
| | alr0790 | ORF_ID:alr0790; hypothetical protein. (351 aa) |
| | all0788 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (240 aa) |
| | alr0782 | Ribulose-phosphate 3-epimerase; ORF_ID:alr0782; Belongs to the ribulose-phosphate 3-epimerase family. (235 aa) |
