STRINGSTRING
all4418 all4418 rfbC-2 rfbC-2 rfbD rfbD alr4529 alr4529 alr4554 alr4554 alr0515 alr0515 asr4648 asr4648 alr0507 alr0507 all0405 all0405 all0282 all0282 alr0277 alr0277 alr0227 alr0227 all4665 all4665 alr4670 alr4670 all4673 all4673 alr4700 alr4700 all4705 all4705 all4708 all4708 all4751 all4751 alr4784 alr4784 alr4795 alr4795 alr4808 alr4808 all4826 all4826 alr4848 alr4848 alr4932 alr4932 alr4943 alr4943 alr5000 alr5000 alr5010 alr5010 all5014 all5014 atpE atpE atpB atpB all5063 all5063 alr5095 alr5095 alr5099 alr5099 all5206 all5206 sigA sigA accA accA nusG nusG atpC atpC atpA atpA atpD atpD atpF atpF atpG atpG atpH atpH atpI atpI alr0051 alr0051 all0066 all0066 alr0068 alr0068 alr0080 alr0080 alr0106 alr0106 all0118 all0118 all0122 all0122 all0174 all0174 alr0212 alr0212 alr4582 alr4582 alr0541 alr0541 dnaB dnaB rfbB-2 rfbB-2 alr0658 alr0658 all0661 all0661 alr0731 alr0731 all0788 all0788 asr0798 asr0798 accC accC purK purK cyaA cyaA alr1155 alr1155 all1162 all1162 alr1207 alr1207 alr1217 alr1217 all1219 all1219 alr1254 alr1254 alr1299 alr1299 all1323 all1323 alr1468 alr1468 rpoB rpoB rpoC1 rpoC1 rpoC2 rpoC2 alr1623 alr1623 all1681 all1681 sigC sigC all1754 all1754 nusB nusB queA queA alr1885 alr1885 alr1912 alr1912 alr1999 alr1999 dnaN dnaN all2063 all2063 all2091 all2091 all2193 all2193 cyaB1 cyaB1 purC purC all2303 all2303 all2333 all2333 alr2350 alr2350 accD accD asr2474 asr2474 alr2475 alr2475 alr2482 alr2482 alr2483 alr2483 alr2485 alr2485 all2529 all2529 ackA ackA all2568 all2568 all2705 all2705 alr2708 alr2708 alr2742 alr2742 rfbC rfbC all2846 all2846 panC panC alr2945 alr2945 all2961 all2961 alr2983 alr2983 all2996 all2996 all3029 all3029 all3054 all3054 purH purH all3111 all3111 all3132 all3132 all3160 all3160 alr3280 alr3280 alr3336 alr3336 alr3339 alr3339 alr3395 alr3395 alr3402 alr3402 alr3407 alr3407 alr3426 alr3426 alr3444 alr3444 alr3497 alr3497 all3500 all3500 alr3510 alr3510 alr3525 alr3525 all3578 all3578 all3581 all3581 alr3583 alr3583 alr3606 alr3606 all3651 all3651 all3652 all3652 all3704 all3704 sigE sigE alr3809 alr3809 sigD sigD alr3829 alr3829 all3853 all3853 alr3885 alr3885 alr3896 alr3896 alr3921 alr3921 alr3925 alr3925 serS serS alr4054 alr4054 alr4161 alr4161 rpoA rpoA all4196 all4196 all4236 all4236 all4248 all4248 sigF sigF all4256 all4256 all4257 all4257 all4272 all4272
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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gene neighborhood
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all4418ORF_ID:all4418; unknown protein. (347 aa)
rfbC-2dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa)
rfbDdTDP-6-deoxy-L-mannose-dehydrogenase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (294 aa)
alr4529ORF_ID:alr4529; hypothetical protein. (214 aa)
alr4554Alr4554 protein; 6-pyruvoyl-tetrahydropterin synthase homolog; ORF_ID:alr4554. (290 aa)
alr0515Alr0515 protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (240 aa)
asr4648DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (78 aa)
alr0507ORF_ID:alr0507; unknown protein. (394 aa)
all0405ORF_ID:all0405; hypothetical protein. (692 aa)
all0282ORF_ID:all0282; unknown protein. (162 aa)
alr0277RNA polymerase sigma-37 factor; ORF_ID:alr0277; Belongs to the sigma-70 factor family. (261 aa)
alr0227NAD kinase 2; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (306 aa)
all4665ORF_ID:all4665; hypothetical protein. (364 aa)
alr4670Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (330 aa)
all4673Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (324 aa)
alr4700Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (191 aa)
all4705All4705 protein; DNA polymerase III, delta prime subunit; ORF_ID:all4705. (320 aa)
all4708Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa)
all4751NAD kinase 1; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (305 aa)
alr4784Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (419 aa)
alr4795ORF_ID:alr4795; hypothetical protein. (157 aa)
alr4808CinA-like protein; ORF_ID:alr4808; competence-damage inducible protein CinA homolog; Belongs to the CinA family. (424 aa)
all4826dTDP-glucose dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (314 aa)
alr4848Riboflavin kinase/FAD synthase; ORF_ID:alr4848; Belongs to the ribF family. (362 aa)
alr4932DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (655 aa)
alr4943Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (337 aa)
alr5000CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
alr5010D-hydantoinase; ORF_ID:alr5010. (496 aa)
all5014ORF_ID:all5014; hypothetical protein. (282 aa)
atpEATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (137 aa)
atpBATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (482 aa)
all5063Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (208 aa)
alr50957-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (229 aa)
alr5099Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (206 aa)
all5206ORF_ID:all5206; probable reverse transcriptase. (539 aa)
sigATranscription initiation factor sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (390 aa)
accAacetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa)
nusGTranscription antitermination protein; Participates in transcription elongation, termination and antitermination. (210 aa)
atpCATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (315 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit; Belongs to the ATPase alpha/beta chains family. (506 aa)
atpDATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (183 aa)
atpFATP synthase subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (187 aa)
atpGATP synthase subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (163 aa)
atpHATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa)
atpIATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (251 aa)
alr0051IMP dehydrogenase; ORF_ID:alr0051. (387 aa)
all0066dCTP deaminase; ORF_ID:all0066. (199 aa)
alr0068Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa)
alr00806-carboxy-5,6,7,8-tetrahydropterin synthase; ORF_ID:alr0080; hypothetical protein. (128 aa)
alr0106Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa)
all0118ORF_ID:all0118; hypothetical protein. (156 aa)
all0122Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
all0174UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (447 aa)
alr0212Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (299 aa)
alr4582Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa)
alr0541ORF_ID:alr0541; hypothetical protein. (160 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity; Belongs to the helicase family. DnaB subfamily. (879 aa)
rfbB-2dTDP-glucose 4-6-dehydratase; ORF_ID:alr0657; rfbB gene product. (311 aa)
alr0658UDP-glucose dehydrogenase; ORF_ID:alr0658. (461 aa)
all0661Adenylate cyclase; ORF_ID:all0661; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (472 aa)
alr0731Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (207 aa)
all0788Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (240 aa)
asr0798ORF_ID:asr0798; hypothetical protein; Belongs to the BolA/IbaG family. (80 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (175 aa)
cyaAAdenylate cyclase; ORF_ID:all1118; cyaA gene product. (735 aa)
alr1155Carbamoyl phosphate synthase small subunit; ORF_ID:alr1155; Belongs to the CarA family. (388 aa)
all1162NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (136 aa)
alr1207Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa)
alr1217L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (578 aa)
all1219ORF_ID:all1219; hypothetical protein. (737 aa)
alr1254DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (977 aa)
alr1299Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (391 aa)
all1323DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (640 aa)
alr1468CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (668 aa)
rpoBRNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1131 aa)
rpoC1RNA polymerase gamma subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (625 aa)
rpoC2RNA polymerase beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily. (1350 aa)
alr1623Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa)
all1681Aspartate carbamoyltransferase; ORF_ID:all1681; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (333 aa)
sigCRNA polymerase sigma-subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (416 aa)
all1754Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (196 aa)
nusBTranscription termination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (211 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (397 aa)
alr1885Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] (339 aa)
alr1912Alr1912 protein; Catalyzes the conversion of dihydroorotate to orotate. (343 aa)
alr1999ORF_ID:alr1999; hypothetical protein. (216 aa)
dnaNDNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (387 aa)
all2063Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (216 aa)
all2091Nicotinate-nucleotide pyrophosphorylase; ORF_ID:all2091; Belongs to the NadC/ModD family. (287 aa)
all2193ORF_ID:all2193; probable sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa)
cyaB1Adenylate cyclase; ORF_ID:alr2266; cyaB1 gene product. (859 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; ORF_ID:alr2268; purC gene product; Belongs to the SAICAR synthetase family. (245 aa)
all2303Dihydroorotase; ORF_ID:all2303. (439 aa)
all2333ORF_ID:all2333; hypothetical protein. (595 aa)
alr2350Phosphoribulokinase; ORF_ID:alr2350. (313 aa)
accDacetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (316 aa)
asr2474Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (92 aa)
alr2475Phosphoribosylformyl glycinamidine synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (224 aa)
alr2482Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (459 aa)
alr2483Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa)
alr2485NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (566 aa)
all2529ORF_ID:all2529; unknown protein. (453 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
all2568Probable 2-phosphosulfolactate phosphatase; ORF_ID:all2568; hypothetical protein; Belongs to the ComB family. (245 aa)
all2705ORF_ID:all2705; hypothetical protein. (416 aa)
alr2708Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa)
alr2742Phosphoribosyl aminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa)
rfbCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (189 aa)
all2846GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (540 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (534 aa)
alr2945Orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (500 aa)
all2961ORF_ID:all2961; similar to reverse transcriptase. (306 aa)
alr2983Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (238 aa)
all2996Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (321 aa)
all3029ORF_ID:all3029; hypothetical protein. (126 aa)
all3054ORF_ID:all3054; hypothetical protein. (1038 aa)
purHBifunctional purine biosynthesis protein; ORF_ID:all3093; purH gene product. (506 aa)
all3111Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (410 aa)
all3132ABC transport protein, ATP-binding subunit; ORF_ID:all3132. (381 aa)
all3160ORF_ID:all3160; hypothetical protein. (171 aa)
alr3280RNA polymerase sigma-E factor; ORF_ID:alr3280; Belongs to the sigma-70 factor family. ECF subfamily. (218 aa)
alr3336ORF_ID:alr3336; similar to methionine adenosyltransferase. (294 aa)
alr3339Dihydroorotase; ORF_ID:alr3339. (435 aa)
alr3395Adenylosuccinate lyase; ORF_ID:alr3395; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa)
alr3402Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (117 aa)
alr3407ORF_ID:alr3407; similar to abortive phage resistance protein. (201 aa)
alr3426ORF_ID:alr3426; hypothetical protein. (123 aa)
alr3444ORF_ID:alr3444; hypothetical protein. (329 aa)
alr3497ORF_ID:alr3497; hypothetical protein. (352 aa)
all3500ORF_ID:all3500; unknown protein. (1025 aa)
alr3510Phosphoribosylamine--glycine ligase; ORF_ID:alr3510. (425 aa)
alr3525Phosphoribosylformylglycinamidine cyclo-ligase; ORF_ID:alr3525. (425 aa)
all3578DNA polymerase III alpha subunit; ORF_ID:all3578. (877 aa)
all3581ORF_ID:all3581; unknown protein. (409 aa)
alr3583ORF_ID:alr3583; unknown protein. (213 aa)
alr3606Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. (430 aa)
all3651Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (499 aa)
all3652Phosphoribosylformyl glycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (782 aa)
all3704ORF_ID:all3704; probable phosphoribosyltransferase. (172 aa)
sigEGroup 2 sigma 70-type sigma factor E; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (327 aa)
alr3809Carbamoyl phosphate synthetase large chain; ORF_ID:alr3809. (1104 aa)
sigDGroup 2 sigma 70-type sigma factor D; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (332 aa)
alr3829Transcription termination factor; Participates in both transcription termination and antitermination. (425 aa)
all3853Group 3 sigma 37-type sigma factor; ORF_ID:all3853; Belongs to the sigma-70 factor family. (258 aa)
alr3885ORF_ID:alr3885; probable phosphoribosylaminoimidazole carboxylase catalytic subunit. (262 aa)
alr3896Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (276 aa)
alr3921UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa)
alr3925ORF_ID:alr3925; hypothetical protein. (987 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa)
alr40545'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (274 aa)
alr41617-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (264 aa)
rpoARNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (315 aa)
all4196Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa)
all4236ORF_ID:all4236; unknown protein. (113 aa)
all4248Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (846 aa)
sigFGroup 2 sigma 70-type sigma factor F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (390 aa)
all4256Acetyl-coenzyme A synthetase; ORF_ID:all4256. (132 aa)
all4257Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (524 aa)
all4272Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (376 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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