STRINGSTRING
devB devB fdxH fdxH xisC xisC alr0583 alr0583 patA patA hetR hetR glnA glnA hepA hepA asr3935 asr3935 hetN hetN alr1603 alr1603 patS patS xisA xisA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
devBglucose-6-P-dehydrogenase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. (240 aa)
fdxHHeterocyst ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Donates electrons to the nitrogenase. (99 aa)
xisChupL element site-specific recombinase; Essential for DNA excision. Site specific recombinase necessary for the excision of the 10.5 kb hupL element during heterocyst differentiation. (498 aa)
alr0583ATP-binding protein of ABC transporter; ORF_ID:alr0583. (746 aa)
patATwo-component response regulator, heterocyst pattern formation protein; Controls heterocyst pattern formation. Required for the differentiation of intercalary heterocysts but not for terminal heterocysts. (379 aa)
hetRHeterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. (299 aa)
glnAGlutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (474 aa)
hepAATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. (607 aa)
asr3935DNA binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. It is essential for heterocyst differentiation; Belongs to the bacterial histone-like protein family. (94 aa)
hetNKetoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. (287 aa)
alr1603Protein FraH; Putative heterocyst to vegetative cell connection. (289 aa)
patSHeterocyst-inhibiting signaling peptide; Inhibits heterocyst differentiation. Seems to control heterocyst pattern formation through intercellular signaling mechanisms. In Anabaena filaments every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation. Seems to inhibit the formation of adjacent heterocysts. Inhibits the DNA-binding of HetR. (17 aa)
xisAnifD element site-specific recombinase; Essential for DNA excision. Site specific recombinase necessary for the excision of the 11 kb nifD element during heterocyst differentiation. (472 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
Server load: low (18%) [HD]