node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alr0583 | hepA | gene:10492594 | gene:10494869 | ATP-binding protein of ABC transporter; ORF_ID:alr0583. | ATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. | 0.912 |
alr1603 | devB | gene:10493619 | gene:10493618 | Protein FraH; Putative heterocyst to vegetative cell connection. | glucose-6-P-dehydrogenase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. | 0.518 |
devB | alr1603 | gene:10493618 | gene:10493619 | glucose-6-P-dehydrogenase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. | Protein FraH; Putative heterocyst to vegetative cell connection. | 0.518 |
glnA | hetR | gene:10494357 | gene:10494368 | Glutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | 0.658 |
glnA | xisA | gene:10494357 | gene:10493457 | Glutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | nifD element site-specific recombinase; Essential for DNA excision. Site specific recombinase necessary for the excision of the 11 kb nifD element during heterocyst differentiation. | 0.460 |
hepA | alr0583 | gene:10494869 | gene:10492594 | ATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. | ATP-binding protein of ABC transporter; ORF_ID:alr0583. | 0.912 |
hepA | hetN | gene:10494869 | gene:10497420 | ATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | 0.462 |
hepA | hetR | gene:10494869 | gene:10494368 | ATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | 0.760 |
hepA | patS | gene:10494869 | gene:10494330 | ATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. | Heterocyst-inhibiting signaling peptide; Inhibits heterocyst differentiation. Seems to control heterocyst pattern formation through intercellular signaling mechanisms. In Anabaena filaments every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation. Seems to inhibit the formation of adjacent heterocysts. Inhibits the DNA-binding of HetR. | 0.600 |
hetN | hepA | gene:10497420 | gene:10494869 | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | ATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. | 0.462 |
hetN | hetR | gene:10497420 | gene:10494368 | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | 0.916 |
hetN | patA | gene:10497420 | gene:10492532 | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | Two-component response regulator, heterocyst pattern formation protein; Controls heterocyst pattern formation. Required for the differentiation of intercalary heterocysts but not for terminal heterocysts. | 0.730 |
hetN | patS | gene:10497420 | gene:10494330 | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | Heterocyst-inhibiting signaling peptide; Inhibits heterocyst differentiation. Seems to control heterocyst pattern formation through intercellular signaling mechanisms. In Anabaena filaments every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation. Seems to inhibit the formation of adjacent heterocysts. Inhibits the DNA-binding of HetR. | 0.916 |
hetR | glnA | gene:10494368 | gene:10494357 | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | Glutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.658 |
hetR | hepA | gene:10494368 | gene:10494869 | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | ATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. | 0.760 |
hetR | hetN | gene:10494368 | gene:10497420 | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | 0.916 |
hetR | patA | gene:10494368 | gene:10492532 | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | Two-component response regulator, heterocyst pattern formation protein; Controls heterocyst pattern formation. Required for the differentiation of intercalary heterocysts but not for terminal heterocysts. | 0.768 |
hetR | patS | gene:10494368 | gene:10494330 | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | Heterocyst-inhibiting signaling peptide; Inhibits heterocyst differentiation. Seems to control heterocyst pattern formation through intercellular signaling mechanisms. In Anabaena filaments every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation. Seems to inhibit the formation of adjacent heterocysts. Inhibits the DNA-binding of HetR. | 0.916 |
patA | hetN | gene:10492532 | gene:10497420 | Two-component response regulator, heterocyst pattern formation protein; Controls heterocyst pattern formation. Required for the differentiation of intercalary heterocysts but not for terminal heterocysts. | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | 0.730 |
patA | hetR | gene:10492532 | gene:10494368 | Two-component response regulator, heterocyst pattern formation protein; Controls heterocyst pattern formation. Required for the differentiation of intercalary heterocysts but not for terminal heterocysts. | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | 0.768 |