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minD-3 minD-3 alr3472 alr3472 alr3513 alr3513 alr3592 alr3592 all3678 all3678 alr3739 alr3739 alr3828 alr3828 alr3844 alr3844 psbO psbO ftsZ ftsZ all3861 all3861 all3873 all3873 alr3921 alr3921 all3927 all3927 alr3980 alr3980 all4107 all4107 alr4112 alr4112 typA typA alr4169 alr4169 petN petN all4316 all4316 all4341 all4341 all4384 all4384 alr4537 alr4537 all4578 all4578 all4680 all4680 alr4714 alr4714 all4768 all4768 alr4769 alr4769 all4770 all4770 alr4807 alr4807 alr4810 alr4810 alr4831 alr4831 alr4888 alr4888 alr4893 alr4893 alr5045 alr5045 alr5065 alr5065 alr5066 alr5066 pbpB pbpB all5169 all5169 alr5243 alr5243 murF murF all5250 all5250 rbfA rbfA alr0069 alr0069 alr0075 alr0075 alr0094 alr0094 all0174 all0174 all0185 all0185 all0244 all0244 psbV psbV all0271 all0271 alr0280 alr0280 all0325 all0325 all0355 all0355 alr0477 alr0477 alr0483 alr0483 alr0487 alr0487 alr0522 alr0522 cphA cphA all0646 all0646 alr0652 alr0652 alr0653 alr0653 alr0692 alr0692 alr0733 alr0733 alr0820 alr0820 alr0821 alr0821 alr0912 alr0912 all0936 all0936 all0980 all0980 alr1029 alr1029 alr1030 alr1030 alr1158 alr1158 all1214 all1214 all1220 all1220 psbZ psbZ alr1278 alr1278 asr1309 asr1309 alr1349 alr1349 petG petG all1367 all1367 hesB hesB nifN nifN nifE nifE nifU nifU alr1525 alr1525 all1663 all1663 alr1740 alr1740 all1770 all1770 alr1779 alr1779 all1816 all1816 all1895 all1895 alr1954 alr1954 alr2203 alr2203 all2287 all2287 all2318 all2318 alr2385 alr2385 alr2449 alr2449 alr2467 alr2467 alr2486 alr2486 alr2492 alr2492 alr2494 alr2494 alr2505 alr2505 asl2557 asl2557 all2707 all2707 alr2717 alr2717 alr2718 alr2718 alr2812 alr2812 nifS-2 nifS-2 alr3100 alr3100 ccdA ccdA ycf44 ycf44 alr3182 alr3182 alr3229 alr3229 all3278 all3278 all3354 all3354 alr3417 alr3417 rpl20 rpl20 minC minC
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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minD-3Septum site-determining protein; ORF_ID:alr3456; minD gene product. (268 aa)
alr3472ORF_ID:alr3472; unknown protein. (557 aa)
alr3513ORF_ID:alr3513; hypothetical protein. (144 aa)
alr3592ORF_ID:alr3592; unknown protein. (1033 aa)
all3678Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (589 aa)
alr3739GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (342 aa)
alr3828Ribosome maturation factor RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (153 aa)
alr3844Ycf48-like protein; Unknown. The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity. (339 aa)
psbOManganese-stabilzing protein precursor; MSP binds to a putative Mn-binding protein and keeps 2 of the 4 Mn-atoms associated with PSII. (273 aa)
ftsZCell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (428 aa)
all3861ORF_ID:all3861; unknown protein. (236 aa)
all3873Pseudouridine synthase; ORF_ID:all3873; hypothetical protein; Belongs to the pseudouridine synthase RsuA family. (262 aa)
alr3921UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa)
all3927ORF_ID:all3927; unknown protein. (863 aa)
alr3980ORF_ID:alr3980; hypothetical protein. (176 aa)
all4107Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity). (202 aa)
alr4112UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (462 aa)
typAGTP-binding protein TypA; ORF_ID:all4140; bipA gene product. (596 aa)
alr4169Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (152 aa)
petNPetN protein; Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. (29 aa)
all4316phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (369 aa)
all4341ORF_ID:all4341; hypothetical protein; Belongs to the HesB/IscA family. (112 aa)
all4384ORF_ID:all4384; hypothetical protein. (491 aa)
alr4537ORF_ID:alr4537; hypothetical protein. (252 aa)
all4578ORF_ID:all4578; unknown protein. (202 aa)
all4680Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (285 aa)
alr4714ORF_ID:alr4714; unknown protein. (232 aa)
all4768ORF_ID:all4768; hypothetical protein. (171 aa)
alr4769ORF_ID:alr4769; unknown protein. (227 aa)
all4770ORF_ID:all4770; hypothetical protein. (170 aa)
alr4807ORF_ID:alr4807; probable glycosyltransferase. (348 aa)
alr4810ORF_ID:alr4810; hypothetical protein. (105 aa)
alr4831mRNA-binding protein; ORF_ID:alr4831. (311 aa)
alr4888ORF_ID:alr4888; hypothetical protein. (286 aa)
alr4893ORF_ID:alr4893; hypothetical protein. (676 aa)
alr5045Penicillin-binding protein; ORF_ID:alr5045. (610 aa)
alr5065UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation; Belongs to the MurCDEF family. (494 aa)
alr5066UDP-N-acetylenolpyruvylglucosamine reductase; Cell wall formation. (331 aa)
pbpBPenicillin-binding protein 2; ORF_ID:alr5101. (763 aa)
all5169ORF_ID:all5169; hypothetical protein. (157 aa)
alr5243ORF_ID:alr5243; unknown protein. (192 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (451 aa)
all5250ORF_ID:all5250; hypothetical protein. (361 aa)
rbfARibosome binding facror A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (133 aa)
alr0069Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (247 aa)
alr0075ORF_ID:alr0075; hypothetical protein. (491 aa)
alr0094Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (292 aa)
all0174UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (447 aa)
all0185Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (554 aa)
all0244ORF_ID:all0244; hypothetical protein. (174 aa)
psbVCytochrome c550; Low-potential cytochrome c that plays a role in the oxygen- evolving complex of photosystem II. (163 aa)
all0271Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (184 aa)
alr0280Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (228 aa)
all0325ORF_ID:all0325; hypothetical protein. (244 aa)
all0355Probable dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (322 aa)
alr0477phospho-N-acetylmuramoyl-pentapeptide- transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (261 aa)
alr0483GTP binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (453 aa)
alr0487Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (198 aa)
alr0522Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (312 aa)
cphACyanophycin synthetase; ORF_ID:alr0573; cphA gene product. (636 aa)
all0646Protein Thf1; May be involved in photosynthetic membrane biogenesis. (233 aa)
alr0652Iron-sulfur cluster carrier protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (356 aa)
alr0653Peptidoglycan glycosyltransferase RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (438 aa)
alr0692ORF_ID:alr0692; similar to NifU protein. (158 aa)
alr0733Urease accessory protein E; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (147 aa)
alr0820Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (449 aa)
alr0821ORF_ID:alr0821; hypothetical protein. (140 aa)
alr0912GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (337 aa)
all0936C-type cytochrome synthesis protein; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. (351 aa)
all0980D-alanyl-D-alanine ligase; Cell wall formation. (364 aa)
alr1029ORF_ID:alr1029; hypothetical protein. (255 aa)
alr1030ORF_ID:alr1030; hypothetical protein. (253 aa)
alr1158Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (161 aa)
all1214Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (320 aa)
all1220ORF_ID:all1220; hypothetical protein. (327 aa)
psbZPhotosystem II 11 kD protein; Plays a role in the repair and/or biogenesis of the calcium- manganese-oxide cluster on the lumenal face of the thylakoid membrane. Its presence in a photosystem II (PSII) preparation prevents binding of some small extrinsic subunits and thus assembly of calcium-manganese- oxide cluster. (133 aa)
alr1278ORF_ID:alr1278; hypothetical protein. (865 aa)
asr1309NifU like protein; ORF_ID:asr1309. (76 aa)
alr1349Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (235 aa)
petGCytochrome b6-f complex subunit 5; Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex. (37 aa)
all1367ORF_ID:all1367; hypothetical protein. (184 aa)
hesBHesB protein; May be required for efficient nitrogen fixation. (123 aa)
nifNNitrogenase olybdenum-iron protein; This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor); Belongs to the NifD/NifK/NifE/NifN family. (444 aa)
nifENitrogen Fe/Mo cofactor biosynthesis E; This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor); Belongs to the NifD/NifK/NifE/NifN family. (480 aa)
nifUNitrogen fixation protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. (300 aa)
alr1525ORF_ID:alr1525; hypothetical protein. (132 aa)
all1663UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
alr1740ORF_ID:alr1740; unknown protein. (132 aa)
all1770ORF_ID:all1770; unknown protein. (340 aa)
alr1779ORF_ID:alr1779; similar to cyanophycin synthetase. (333 aa)
all1816ORF_ID:all1816; hypothetical protein. (215 aa)
all1895ORF_ID:all1895; probable glycosyl transferase. (360 aa)
alr1954ORF_ID:alr1954; hypothetical protein. (138 aa)
alr2203ORF_ID:alr2203; hypothetical protein. (283 aa)
all2287Glucosyltransferase; ORF_ID:all2287. (151 aa)
all2318ORF_ID:all2318; hypothetical protein. (264 aa)
alr2385ORF_ID:alr2385; hypothetical protein; Belongs to the HesB/IscA family. (118 aa)
alr2449Small ribosomal subunit biogenesis GTPase RsgA 1; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (370 aa)
alr2467ORF_ID:alr2467; hypothetical protein. (263 aa)
alr2486ABC transporter ATP-binding protein; ORF_ID:alr2486. (300 aa)
alr2492ORF_ID:alr2492; probable ABC transporter membrane protein (ycf24). (479 aa)
alr2494ORF_ID:alr2494; hypothetical protein. (453 aa)
alr2505Cysteine desulfurase IscS; ORF_ID:alr2505; putative aminotransferase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (388 aa)
asl2557ORF_ID:asl2557; hypothetical protein. (80 aa)
all2707ORF_ID:all2707; hypothetical protein. (798 aa)
alr2717ORF_ID:alr2717; hypothetical protein. (447 aa)
alr2718ORF_ID:alr2718; probable cobyric acid synthase. (273 aa)
alr2812Probable 16S rRNA-processing protein RimM; Essential for efficient processing of 16S rRNA. Probably part of the 30S subunit prior to or during the final step in the processing of 16S free 30S ribosomal subunits. It could be some accessory protein needed for efficient assembly of the 30S subunit. It is needed in a step prior to RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity); Belongs to the RimM family. (246 aa)
nifS-2class-V aminotransferase; ORF_ID:alr3088; nifS gene product. (387 aa)
alr3100Putative pre-16S rRNA nuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (151 aa)
ccdAORF_ID:alr3122; putative c-type cytochrome biogenesis protein CcdA. (246 aa)
ycf44C-type cytochrome biogenesis protein Ccs1; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. (461 aa)
alr3182Glucose inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (245 aa)
alr3229rRNA (adenine-N6,N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (271 aa)
all3278ORF_ID:all3278; hypothetical protein. (272 aa)
all3354Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (302 aa)
alr3417ORF_ID:alr3417; hypothetical protein. (169 aa)
rpl2050S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
minCSeptum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity). In the C-terminal section; belongs to the MinC family. (366 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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