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alr4112 alr4112 all4316 all4316 all2390 all2390 alr4701 alr4701 alr5065 alr5065 alr5066 alr5066 all5166 all5166 asr2565 asr2565 murF murF minD-2 minD-2 alr3363 alr3363 minC minC minD-3 minD-3 minE minE alr3681 alr3681 ftsZ ftsZ alr3857 alr3857 ftsW ftsW all0174 all0174 alr0477 alr0477 alr0487 alr0487 alr0653 alr0653 asl0940 asl0940 alr0943 alr0943 alr0944 alr0944 all1663 all1663 ftsE ftsE all1756 all1756 all1757 all1757 all1872 all1872 minD minD asl2061 asl2061 all2287 all2287
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
alr4112UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (462 aa)
all4316phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (369 aa)
all2390Cell division inhibitor; ORF_ID:all2390. (306 aa)
alr4701ORF_ID:alr4701; hypothetical protein. (147 aa)
alr5065UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation; Belongs to the MurCDEF family. (494 aa)
alr5066UDP-N-acetylenolpyruvylglucosamine reductase; Cell wall formation. (331 aa)
all5166Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (198 aa)
asr2565ORF_ID:asr2565; unknown protein. (67 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (451 aa)
minD-2Cell division inhibitor; ORF_ID:all2797; minD gene product. (249 aa)
alr3363ORF_ID:alr3363; hypothetical protein. (496 aa)
minCSeptum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity). In the C-terminal section; belongs to the MinC family. (366 aa)
minD-3Septum site-determining protein; ORF_ID:alr3456; minD gene product. (268 aa)
minESeptum site-determining protein; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (97 aa)
alr3681Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (471 aa)
ftsZCell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (428 aa)
alr3857ORF_ID:alr3857; hypothetical protein. (281 aa)
ftsWCell division protein; ORF_ID:all0154; ftsW gene product; Belongs to the SEDS family. (396 aa)
all0174UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (447 aa)
alr0477phospho-N-acetylmuramoyl-pentapeptide- transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (261 aa)
alr0487Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (198 aa)
alr0653Peptidoglycan glycosyltransferase RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (438 aa)
asl0940ORF_ID:asl0940; hypothetical protein. (97 aa)
alr0943ORF_ID:alr0943; hypothetical protein. (186 aa)
alr0944ORF_ID:alr0944; hypothetical protein. (173 aa)
all1663UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
ftsECell-division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division. (218 aa)
all1756ORF_ID:all1756; hypothetical protein. (273 aa)
all1757Cell-division protein; ORF_ID:all1757; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (300 aa)
all1872ORF_ID:all1872; hypothetical protein. (503 aa)
minDCell division inhibitor; ORF_ID:all2033; minD gene product. (262 aa)
asl2061ORF_ID:asl2061; hypothetical protein. (92 aa)
all2287Glucosyltransferase; ORF_ID:all2287. (151 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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