STRINGSTRING
accC accC alr1921 alr1921 fabG-2 fabG-2 all1694 all1694 all2635 all2635 asl1650 asl1650 all1649 all1649 all1648 all1648 hglE hglE all1644 all1644 all1643 all1643 desA desA all1522 all1522 accD accD hglC hglC hglD hglD alr5353 alr5353 accB accB all4667 all4667 all4391 all4391 alr2271 alr2271 all4286 all4286 alr4059 alr4059 alr3926 alr3926 accA accA all3569 all3569 alr3343 alr3343 asr3342 asr3342 alr2948 alr2948 panC panC alr2680 alr2680 alr2679 alr2679 all2646 all2646 all1319 all1319 all0938 all0938 all0412 all0412 bioF bioF alr0240 alr0240 alr0239 alr0239 plsX plsX alr1282 alr1282
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
alr1921Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (335 aa)
fabG-23-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (251 aa)
all1694Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (291 aa)
all2635Polyketide synthase type I; ORF_ID:all2635. (1565 aa)
asl1650ORF_ID:asl1650; similar to polyketide synthase. (85 aa)
all1649ORF_ID:all1649; similar to polyketide synthase. (1570 aa)
all1648ORF_ID:all1648; similar to polyketide synthase. (1587 aa)
hglEHeterocyst glycolipid synthase; ORF_ID:all1646; hglE gene product. (1263 aa)
all1644ORF_ID:all1644; hypothetical protein. (585 aa)
all1643ORF_ID:all1643; hypothetical protein. (1601 aa)
desAPhosphatidylcholine desaturase; ORF_ID:all1598; desA gene product. (350 aa)
all15223-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (257 aa)
accDacetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (316 aa)
hglCHeterocyst glycolipid synthase; ORF_ID:alr5355; hglC gene product; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (1109 aa)
hglDHeterocyst glycolipid synthase; ORF_ID:alr5354; hglD gene product; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (453 aa)
alr5353ORF_ID:alr5353; hypothetical protein. (570 aa)
accBBiotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (182 aa)
all4667Dethiobiotin synthase; ORF_ID:all4667; hypothetical protein. (187 aa)
all4391Enoyl-[acyl-carrier-protein] reductase; Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. (264 aa)
alr2271(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (171 aa)
all42863-oxoacyl-[acyl-carrier-protein] synthase; ORF_ID:all4286; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (388 aa)
alr4059ORF_ID:alr4059; unknown protein. (126 aa)
alr3926ORF_ID:alr3926; unknown protein. (442 aa)
accAacetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa)
all3569Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa)
alr33433-oxoacyl-[acyl-carrier-protein] synthase beta chain; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (416 aa)
asr3342Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (84 aa)
alr2948ORF_ID:alr2948; putative zinc-binding oxidoreductase. (335 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (534 aa)
alr2680Polyketide synthase; ORF_ID:alr2680. (2518 aa)
alr2679Polyketide synthase; ORF_ID:alr2679. (2478 aa)
all2646Polyketide synthase type I; ORF_ID:all2646. (1488 aa)
all13192-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (319 aa)
all0938ORF_ID:all0938; hypothetical protein. (137 aa)
all0412ORF_ID:all0412; putative zinc-binding oxidoreductase. (318 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (386 aa)
alr0240Malonyl coenzyme A-acyl carrier protein transacylase; ORF_ID:alr0240. (292 aa)
alr0239Beta-ketoacyl-acyl carrier protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (330 aa)
plsXFatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (341 aa)
alr1282Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (300 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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