STRINGSTRING
moeA moeA atpC atpC atpA atpA atpD atpD atpF atpF atpG atpG atpH atpH atpI atpI alr0051 alr0051 all0066 all0066 alr0068 alr0068 alr0106 alr0106 all0122 all0122 alr0212 alr0212 alr0227 alr0227 alr0234 alr0234 plsX plsX alr0241 alr0241 all0250 all0250 all0251 all0251 all0270 all0270 all0282 all0282 alr0386 alr0386 all0405 all0405 all0492 all0492 alr0515 alr0515 alr0599 alr0599 all0661 all0661 all0788 all0788 alr0790 alr0790 all0800 all0800 all0850 all0850 accC accC all0961 all0961 alr0981 alr0981 thiC thiC all0985 all0985 purK purK cyaA cyaA alr1155 alr1155 alr1207 alr1207 alr1217 alr1217 all1219 all1219 alr1233 alr1233 all1248 all1248 alr1299 alr1299 alr1343 alr1343 asr1344 asr1344 alr1623 alr1623 moaE moaE all1681 all1681 all1693 all1693 all1754 all1754 all1876 all1876 alr1912 alr1912 all2063 all2063 all2091 all2091 cyaB1 cyaB1 purC purC alr2270 alr2270 alr2271 alr2271 alr2272 alr2272 lpxB lpxB all2303 all2303 all2333 all2333 alr2350 alr2350 accD accD asr2474 asr2474 alr2475 alr2475 alr2482 alr2482 alr2483 alr2483 alr2485 alr2485 all2501 all2501 ackA ackA alr2708 alr2708 alr2742 alr2742 all2846 all2846 alr2881 alr2881 all2917 all2917 panC panC alr2945 alr2945 alr2983 alr2983 all2996 all2996 all3029 all3029 alr3074 alr3074 purH purH all3111 all3111 all3160 all3160 alr3230 alr3230 asr3294 asr3294 alr3339 alr3339 alr3382 alr3382 alr3395 alr3395 alr3402 alr3402 alr3510 alr3510 thiG thiG alr3525 alr3525 alr3606 alr3606 all3651 all3651 all3652 all3652 all3704 all3704 alr3809 alr3809 all3865 all3865 all3875 all3875 alr3883 alr3883 alr3885 alr3885 alr3896 alr3896 alr3921 alr3921 alr4005 alr4005 alr4036 alr4036 all4063 all4063 all4196 all4196 alr4223 alr4223 all4256 all4256 all4257 all4257 all4272 all4272 all4348 all4348 all4349 all4349 all4350 all4350 alr4351 alr4351 asl4353 asl4353 alr4582 alr4582 all4665 all4665 alr4670 alr4670 all4673 all4673 amt1 amt1 alr4700 alr4700 all4708 all4708 all4721 all4721 all4751 all4751 pdxA pdxA alr4784 alr4784 alr4795 alr4795 alr4808 alr4808 alr4848 alr4848 all4871 all4871 alr5000 alr5000 alr5010 alr5010 atpE atpE atpB atpB all5052 all5052 alr5061 alr5061 all5063 all5063 alr5099 alr5099 all5167 all5167 accA accA alr5287 alr5287
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
moeAMolybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP; Belongs to the MoeA family. (436 aa)
atpCATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (315 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit; Belongs to the ATPase alpha/beta chains family. (506 aa)
atpDATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (183 aa)
atpFATP synthase subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (187 aa)
atpGATP synthase subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (163 aa)
atpHATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa)
atpIATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (251 aa)
alr0051IMP dehydrogenase; ORF_ID:alr0051. (387 aa)
all0066dCTP deaminase; ORF_ID:all0066. (199 aa)
alr0068Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa)
alr0106Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa)
all0122Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
alr0212Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (299 aa)
alr0227NAD kinase 2; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (306 aa)
alr0234ORF_ID:alr0234; unknown protein. (241 aa)
plsXFatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (341 aa)
alr0241ORF_ID:alr0241; putative acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (212 aa)
all0250ORF_ID:all0250; hypothetical protein. (275 aa)
all0251ORF_ID:all0251; hypothetical protein. (276 aa)
all0270Diacylglycerol kinase; ORF_ID:all0270. (151 aa)
all0282ORF_ID:all0282; unknown protein. (162 aa)
alr0386ORF_ID:alr0386; hypothetical protein. (444 aa)
all0405ORF_ID:all0405; hypothetical protein. (692 aa)
all0492Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (226 aa)
alr0515Alr0515 protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (240 aa)
alr05991-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (635 aa)
all0661Adenylate cyclase; ORF_ID:all0661; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (472 aa)
all0788Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (240 aa)
alr0790ORF_ID:alr0790; hypothetical protein. (351 aa)
all0800Molybdopterin precursor biosynthesis protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (167 aa)
all0850ORF_ID:all0850; putative acyltransferase. (314 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
all0961Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (207 aa)
alr0981ORF_ID:alr0981; hypothetical protein. (282 aa)
thiCThiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (457 aa)
all09854-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (402 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (175 aa)
cyaAAdenylate cyclase; ORF_ID:all1118; cyaA gene product. (735 aa)
alr1155Carbamoyl phosphate synthase small subunit; ORF_ID:alr1155; Belongs to the CarA family. (388 aa)
alr1207Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa)
alr1217L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (578 aa)
all1219ORF_ID:all1219; hypothetical protein. (737 aa)
alr1233ORF_ID:alr1233; hypothetical protein. (276 aa)
all1248Pyridoxamine 5-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa)
alr1299Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (391 aa)
alr1343Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (379 aa)
asr1344ORF_ID:asr1344; hypothetical protein. (70 aa)
alr1623Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa)
moaEMolybdopterin converting factor, subunit 2; Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family. (165 aa)
all1681Aspartate carbamoyltransferase; ORF_ID:all1681; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (333 aa)
all1693Glycerol-3-phosphate dehydrogenase; ORF_ID:all1693; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (307 aa)
all1754Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (196 aa)
all1876ORF_ID:all1876; hypothetical protein. (323 aa)
alr1912Alr1912 protein; Catalyzes the conversion of dihydroorotate to orotate. (343 aa)
all2063Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (216 aa)
all2091Nicotinate-nucleotide pyrophosphorylase; ORF_ID:all2091; Belongs to the NadC/ModD family. (287 aa)
cyaB1Adenylate cyclase; ORF_ID:alr2266; cyaB1 gene product. (859 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; ORF_ID:alr2268; purC gene product; Belongs to the SAICAR synthetase family. (245 aa)
alr2270UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (280 aa)
alr2271(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (171 aa)
alr2272acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine o-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (252 aa)
lpxBLipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (384 aa)
all2303Dihydroorotase; ORF_ID:all2303. (439 aa)
all2333ORF_ID:all2333; hypothetical protein. (595 aa)
alr2350Phosphoribulokinase; ORF_ID:alr2350. (313 aa)
accDacetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (316 aa)
asr2474Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (92 aa)
alr2475Phosphoribosylformyl glycinamidine synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (224 aa)
alr2482Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (459 aa)
alr2483Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa)
alr2485NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (566 aa)
all25014-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (408 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
alr2708Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa)
alr2742Phosphoribosyl aminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa)
all2846GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (540 aa)
alr2881ORF_ID:alr2881; hypothetical protein. (315 aa)
all2917Inositol monophophatase family; ORF_ID:all2917; Belongs to the inositol monophosphatase superfamily. (270 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (534 aa)
alr2945Orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (500 aa)
alr2983Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (238 aa)
all2996Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (321 aa)
all3029ORF_ID:all3029; hypothetical protein. (126 aa)
alr3074UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (349 aa)
purHBifunctional purine biosynthesis protein; ORF_ID:all3093; purH gene product. (506 aa)
all3111Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (410 aa)
all3160ORF_ID:all3160; hypothetical protein. (171 aa)
alr32304-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (317 aa)
asr3294ORF_ID:asr3294; hypothetical protein. (91 aa)
alr3339Dihydroorotase; ORF_ID:alr3339. (435 aa)
alr3382Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (168 aa)
alr3395Adenylosuccinate lyase; ORF_ID:alr3395; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa)
alr3402Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (117 aa)
alr3510Phosphoribosylamine--glycine ligase; ORF_ID:alr3510. (425 aa)
thiGThiamin biosynthesis protein; Catalyzes the FAD-dependent oxidative deamination of glycine. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate; In the N-terminal section; belongs to the DAO family. ThiO subfamily. (652 aa)
alr3525Phosphoribosylformylglycinamidine cyclo-ligase; ORF_ID:alr3525. (425 aa)
alr3606Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. (430 aa)
all3651Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (499 aa)
all3652Phosphoribosylformyl glycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (782 aa)
all3704ORF_ID:all3704; probable phosphoribosyltransferase. (172 aa)
alr3809Carbamoyl phosphate synthetase large chain; ORF_ID:alr3809. (1104 aa)
all3865Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa)
all3875Phosphatidate cytidylyltransferase; ORF_ID:all3875; Belongs to the CDS family. (294 aa)
alr38832-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (165 aa)
alr3885ORF_ID:alr3885; probable phosphoribosylaminoimidazole carboxylase catalytic subunit. (262 aa)
alr3896Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (276 aa)
alr3921UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa)
alr4005ORF_ID:alr4005; hypothetical protein. (418 aa)
alr4036ORF_ID:alr4036; hypothetical protein. (194 aa)
all4063Phosphatidylglycerophosphate synthase; ORF_ID:all4063; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (172 aa)
all4196Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa)
alr4223Cardiolipin synthase; ORF_ID:alr4223; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (480 aa)
all4256Acetyl-coenzyme A synthetase; ORF_ID:all4256. (132 aa)
all4257Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (524 aa)
all4272Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (376 aa)
all4348ORF_ID:all4348; unknown protein. (395 aa)
all4349ORF_ID:all4349; unknown protein. (399 aa)
all4350ORF_ID:all4350; unknown protein. (434 aa)
alr4351Deoxyxylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (399 aa)
asl4353ORF_ID:asl4353; hypothetical protein. (86 aa)
alr4582Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa)
all4665ORF_ID:all4665; hypothetical protein. (364 aa)
alr4670Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (330 aa)
all4673Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (324 aa)
amt1Ammonium transporter protein 1; ORF_ID:alr4682; amt1 gene product. (290 aa)
alr4700Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (191 aa)
all4708Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa)
all4721GTP cyclohydrolase I; ORF_ID:all4721. (216 aa)
all4751NAD kinase 1; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (305 aa)
pdxAPyridoxal phosphate biosynthetic protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (362 aa)
alr4784Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (419 aa)
alr4795ORF_ID:alr4795; hypothetical protein. (157 aa)
alr4808CinA-like protein; ORF_ID:alr4808; competence-damage inducible protein CinA homolog; Belongs to the CinA family. (424 aa)
alr4848Riboflavin kinase/FAD synthase; ORF_ID:alr4848; Belongs to the ribF family. (362 aa)
all4871ORF_ID:all4871; hypothetical protein. (287 aa)
alr5000CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
alr5010D-hydantoinase; ORF_ID:alr5010. (496 aa)
atpEATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (137 aa)
atpBATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (482 aa)
all5052ORF_ID:all5052; hypothetical protein. (458 aa)
alr5061Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (332 aa)
all5063Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (208 aa)
alr5099Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (206 aa)
all51674-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (228 aa)
accAacetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa)
alr5287GTP cyclohydrolase I; ORF_ID:alr5287. (235 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
Server load: low (22%) [HD]