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| alr4554 | Alr4554 protein; 6-pyruvoyl-tetrahydropterin synthase homolog; ORF_ID:alr4554. (290 aa) | ||||
| atpC | ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (315 aa) | ||||
| atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit; Belongs to the ATPase alpha/beta chains family. (506 aa) | ||||
| atpD | ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (183 aa) | ||||
| atpF | ATP synthase subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (187 aa) | ||||
| atpG | ATP synthase subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (163 aa) | ||||
| atpH | ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa) | ||||
| atpI | ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (251 aa) | ||||
| murF | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (451 aa) | ||||
| rfbB | dTDP-glucose 4-6-dehydratase; ORF_ID:alr0038; rfbB gene product; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (356 aa) | ||||
| all0040 | ORF_ID:all0040; unknown protein. (510 aa) | ||||
| alr0055 | ORF_ID:alr0055; hypothetical protein. (547 aa) | ||||
| all0066 | dCTP deaminase; ORF_ID:all0066. (199 aa) | ||||
| alr0068 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa) | ||||
| alr0080 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; ORF_ID:alr0080; hypothetical protein. (128 aa) | ||||
| alr0092 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092. (627 aa) | ||||
| alr0093 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0093. (627 aa) | ||||
| alr0094 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (292 aa) | ||||
| alr0106 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa) | ||||
| all0118 | ORF_ID:all0118; hypothetical protein. (156 aa) | ||||
| all0122 | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa) | ||||
| all0174 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (447 aa) | ||||
| all0185 | Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (554 aa) | ||||
| alr0230 | ORF_ID:alr0230; unknown protein. (535 aa) | ||||
| all0244 | ORF_ID:all0244; hypothetical protein. (174 aa) | ||||
| all0250 | ORF_ID:all0250; hypothetical protein. (275 aa) | ||||
| all0251 | ORF_ID:all0251; hypothetical protein. (276 aa) | ||||
| alr0477 | phospho-N-acetylmuramoyl-pentapeptide- transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (261 aa) | ||||
| alr0480 | ORF_ID:alr0480; hypothetical protein. (274 aa) | ||||
| alr0512 | ORF_ID:alr0512; hypothetical protein. (268 aa) | ||||
| alr0515 | Alr0515 protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (240 aa) | ||||
| alr0541 | ORF_ID:alr0541; hypothetical protein. (160 aa) | ||||
| alr0558 | ORF_ID:alr0558; probable glycosyltransferase. (1013 aa) | ||||
| all0562 | ORF_ID:all0562; hypothetical protein. (739 aa) | ||||
| alr0564 | ORF_ID:alr0564; hypothetical protein. (397 aa) | ||||
| cphA | Cyanophycin synthetase; ORF_ID:alr0573; cphA gene product. (636 aa) | ||||
| alr0586 | ORF_ID:alr0586; unknown protein. (331 aa) | ||||
| alr0587 | ORF_ID:alr0587; unknown protein. (311 aa) | ||||
| alr0599 | 1-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (635 aa) | ||||
| alr0653 | Peptidoglycan glycosyltransferase RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (438 aa) | ||||
| rfbB-2 | dTDP-glucose 4-6-dehydratase; ORF_ID:alr0657; rfbB gene product. (311 aa) | ||||
| alr0658 | UDP-glucose dehydrogenase; ORF_ID:alr0658. (461 aa) | ||||
| alr0725 | ORF_ID:alr0725; hypothetical protein. (148 aa) | ||||
| all0727 | glucosamine-6-P isomerase; ORF_ID:all0727. (258 aa) | ||||
| alr0731 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (207 aa) | ||||
| all0746 | ORF_ID:all0746; hypothetical protein. (159 aa) | ||||
| alr0782 | Ribulose-phosphate 3-epimerase; ORF_ID:alr0782; Belongs to the ribulose-phosphate 3-epimerase family. (235 aa) | ||||
| all0788 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (240 aa) | ||||
| all0888 | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (236 aa) | ||||
| accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) | ||||
| all0980 | D-alanyl-D-alanine ligase; Cell wall formation. (364 aa) | ||||
| all0985 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (402 aa) | ||||
| all0988 | N-acetyl-glucosamine-6-phosphate deacetylase; ORF_ID:all0988. (399 aa) | ||||
| purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (175 aa) | ||||
| alr1050 | Glucose-6-phosphate isomerase; ORF_ID:alr1050. (528 aa) | ||||
| gap3 | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG; Belongs to the glyceraldehyde-3-phosphate dehydrogenase [...] (337 aa) | ||||
| alr1112 | ORF_ID:alr1112; probable transglycosylase. (731 aa) | ||||
| alr1155 | Carbamoyl phosphate synthase small subunit; ORF_ID:alr1155; Belongs to the CarA family. (388 aa) | ||||
| all1162 | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (136 aa) | ||||
| alr1167 | Lysin; ORF_ID:alr1167. (242 aa) | ||||
| alr1207 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa) | ||||
| all1214 | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (320 aa) | ||||
| alr1242 | ORF_ID:alr1242; unknown protein. (221 aa) | ||||
| alr1299 | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (391 aa) | ||||
| all1316 | ORF_ID:all1316; unknown protein. (523 aa) | ||||
| alr1324 | ORF_ID:alr1324; unknown protein. (450 aa) | ||||
| alr1364 | ORF_ID:alr1364; hypothetical protein. (354 aa) | ||||
| all1549 | (p)ppGpp 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (751 aa) | ||||
| all1573 | ORF_ID:all1573; unknown protein. (194 aa) | ||||
| devB | glucose-6-P-dehydrogenase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. (240 aa) | ||||
| all1606 | ORF_ID:all1606; hypothetical protein. (431 aa) | ||||
| alr1623 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa) | ||||
| all1663 | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa) | ||||
| all1681 | Aspartate carbamoyltransferase; ORF_ID:all1681; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (333 aa) | ||||
| all1693 | Glycerol-3-phosphate dehydrogenase; ORF_ID:all1693; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (307 aa) | ||||
| alr1740 | ORF_ID:alr1740; unknown protein. (132 aa) | ||||
| alr1744 | Sulfolipid biosynthesis protein; ORF_ID:alr1744. (384 aa) | ||||
| all1754 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (196 aa) | ||||
| alr1779 | ORF_ID:alr1779; similar to cyanophycin synthetase. (333 aa) | ||||
| queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (397 aa) | ||||
| all1811 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (500 aa) | ||||
| all1816 | ORF_ID:all1816; hypothetical protein. (215 aa) | ||||
| alr1885 | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] (339 aa) | ||||
| all1895 | ORF_ID:all1895; probable glycosyl transferase. (360 aa) | ||||
| all1908 | ORF_ID:all1908; unknown protein. (190 aa) | ||||
| alr1912 | Alr1912 protein; Catalyzes the conversion of dihydroorotate to orotate. (343 aa) | ||||
| alr1913 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (357 aa) | ||||
| alr1954 | ORF_ID:alr1954; hypothetical protein. (138 aa) | ||||
| all2063 | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (216 aa) | ||||
| alr2076 | ORF_ID:alr2076; hypothetical protein. (539 aa) | ||||
| purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; ORF_ID:alr2268; purC gene product; Belongs to the SAICAR synthetase family. (245 aa) | ||||
| alr2270 | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (280 aa) | ||||
| alr2271 | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (171 aa) | ||||
| alr2272 | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine o-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (252 aa) | ||||
| lpxB | Lipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (384 aa) | ||||
| all2286 | Glucosyltransferase; ORF_ID:all2286. (169 aa) | ||||
| all2287 | Glucosyltransferase; ORF_ID:all2287. (151 aa) | ||||
| all2292 | ORF_ID:all2292; probable glycosyltransferase. (392 aa) | ||||
| alr2295 | ORF_ID:alr2295; unknown protein. (465 aa) | ||||
| alr2296 | ORF_ID:alr2296; unknown protein. (426 aa) | ||||
| alr2350 | Phosphoribulokinase; ORF_ID:alr2350. (313 aa) | ||||
| accD | acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (316 aa) | ||||
| all2396 | ORF_ID:all2396; unknown protein. (454 aa) | ||||
| all2425 | ORF_ID:all2425; unknown protein. (255 aa) | ||||
| alr2432 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (307 aa) | ||||
| alr2467 | ORF_ID:alr2467; hypothetical protein. (263 aa) | ||||
| asr2474 | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (92 aa) | ||||
| alr2475 | Phosphoribosylformyl glycinamidine synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (224 aa) | ||||
| all2497 | UDP-N-acetyl glucosamine-2-epimerase; ORF_ID:all2497; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (370 aa) | ||||
| all2501 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (408 aa) | ||||
| ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa) | ||||
| tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (332 aa) | ||||
| all2564 | Pyruvate kinase; ORF_ID:all2564; Belongs to the pyruvate kinase family. (476 aa) | ||||
| gap1 | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. (343 aa) | ||||
| all2568 | Probable 2-phosphosulfolactate phosphatase; ORF_ID:all2568; hypothetical protein; Belongs to the ComB family. (245 aa) | ||||
| alr2708 | Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa) | ||||
| alr2717 | ORF_ID:alr2717; hypothetical protein. (447 aa) | ||||
| alr2718 | ORF_ID:alr2718; probable cobyric acid synthase. (273 aa) | ||||
| alr2742 | Phosphoribosyl aminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) | ||||
| alr2752 | Lysozyme; ORF_ID:alr2752; hypothetical protein. (197 aa) | ||||
| alr2816 | ORF_ID:alr2816; hypothetical protein. (804 aa) | ||||
| alr2827 | ORF_ID:alr2827; putative epimerase/dehydratase. (342 aa) | ||||
| rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (189 aa) | ||||
| alr2833 | ORF_ID:alr2833; hypothetical protein. (771 aa) | ||||
| all2846 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (540 aa) | ||||
| alr2856 | ORF_ID:alr2856; hypothetical protein. (736 aa) | ||||
| all2870 | ORF_ID:all2870; unknown protein. (641 aa) | ||||
| alr2933 | Membrane-bound lytic transglycosylase A; ORF_ID:alr2933. (410 aa) | ||||
| alr2935 | Probable endolytic peptidoglycan transglycosylase RlpA; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (371 aa) | ||||
| alr2945 | Orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (500 aa) | ||||
| alr2954 | ORF_ID:alr2954; hypothetical protein. (182 aa) | ||||
| alr2973 | Glucokinase; ORF_ID:alr2973; Belongs to the bacterial glucokinase family. (342 aa) | ||||
| alr2983 | Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (238 aa) | ||||
| all2996 | Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (321 aa) | ||||
| all3029 | ORF_ID:all3029; hypothetical protein. (126 aa) | ||||
| alr3059 | ORF_ID:alr3059; similar to polysaccharide export protein. (727 aa) | ||||
| alr3060 | ORF_ID:alr3060; unknown protein. (469 aa) | ||||
| alr3074 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (349 aa) | ||||
| purH | Bifunctional purine biosynthesis protein; ORF_ID:all3093; purH gene product. (506 aa) | ||||
| all3111 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (410 aa) | ||||
| alr3139 | Putative 5'-nucleotidase alr3139; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (226 aa) | ||||
| alr3150 | ORF_ID:alr3150; hypothetical protein. (486 aa) | ||||
| all3160 | ORF_ID:all3160; hypothetical protein. (171 aa) | ||||
| alr3230 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (317 aa) | ||||
| all3274 | UTP-glucose-1-phosphate uridylyltransferase; ORF_ID:all3274. (293 aa) | ||||
| all3278 | ORF_ID:all3278; hypothetical protein. (272 aa) | ||||
| all3286 | ORF_ID:all3286; unknown protein. (290 aa) | ||||
| alr3336 | ORF_ID:alr3336; similar to methionine adenosyltransferase. (294 aa) | ||||
| alr3344 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate; Belongs to the transketolase family. (670 aa) | ||||
| alr3395 | Adenylosuccinate lyase; ORF_ID:alr3395; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) | ||||
| alr3400 | Mannose-1-phosphate guanyltransferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. (389 aa) | ||||
| alr3402 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (117 aa) | ||||
| alr3424 | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (334 aa) | ||||
| nodM | glutamine-fructose-6-P-aminotransferase; ORF_ID:alr3464; nodM gene product. (541 aa) | ||||
| all3509 | Nucleotide sugar epimerase; ORF_ID:all3509. (316 aa) | ||||
| alr3510 | Phosphoribosylamine--glycine ligase; ORF_ID:alr3510. (425 aa) | ||||
| alr3525 | Phosphoribosylformylglycinamidine cyclo-ligase; ORF_ID:alr3525. (425 aa) | ||||
| alr3533 | ORF_ID:alr3533; hypothetical protein. (184 aa) | ||||
| all3538 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa) | ||||
| alr3606 | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. (430 aa) | ||||
| all3651 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (499 aa) | ||||
| all3652 | Phosphoribosylformyl glycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (782 aa) | ||||
| alr3690 | ORF_ID:alr3690; hypothetical protein. (406 aa) | ||||
| all3695 | N-acyl-D-glucosamine 2-epimerase; ORF_ID:all3695. (388 aa) | ||||
| all3704 | ORF_ID:all3704; probable phosphoribosyltransferase. (172 aa) | ||||
| all3735 | Fructose-bisphosphate aldolase class I; ORF_ID:all3735. (360 aa) | ||||
| alr3757 | Cellulose synthase catalytic subunit; ORF_ID:alr3757. (693 aa) | ||||
| all3772 | ORF_ID:all3772; unknown protein. (311 aa) | ||||
| alr3809 | Carbamoyl phosphate synthetase large chain; ORF_ID:alr3809. (1104 aa) | ||||
| alr3883 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (165 aa) | ||||
| alr3885 | ORF_ID:alr3885; probable phosphoribosylaminoimidazole carboxylase catalytic subunit. (262 aa) | ||||
| alr3896 | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (276 aa) | ||||
| all3908 | ORF_ID:all3908; hypothetical protein. (319 aa) | ||||
| all3914 | succinyl-CoA synthetase beta chain; ORF_ID:all3914. (408 aa) | ||||
| alr3921 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa) | ||||
| all3963 | ORF_ID:all3963; hypothetical protein. (105 aa) | ||||
| alr4005 | ORF_ID:alr4005; hypothetical protein. (418 aa) | ||||
| all4008 | Pyruvate kinase; ORF_ID:all4008; Belongs to the pyruvate kinase family. (589 aa) | ||||
| zwf | Glucose 6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (509 aa) | ||||
| tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (381 aa) | ||||
| all4052 | Transketolase; ORF_ID:all4052. (633 aa) | ||||
| alr4054 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (274 aa) | ||||
| all4070 | ORF_ID:all4070; unknown protein. (236 aa) | ||||
| alr4112 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (462 aa) | ||||
| all4125 | ORF_ID:all4125; hypothetical protein. (515 aa) | ||||
| all4127 | ORF_ID:all4127; unknown protein. (564 aa) | ||||
| all4131 | Phosphoglycerate kinase; ORF_ID:all4131. (400 aa) | ||||
| alr4161 | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (264 aa) | ||||
| alr4174 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (226 aa) | ||||
| all4182 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (533 aa) | ||||
| all4196 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa) | ||||
| all4236 | ORF_ID:all4236; unknown protein. (113 aa) | ||||
| all4256 | Acetyl-coenzyme A synthetase; ORF_ID:all4256. (132 aa) | ||||
| all4257 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (524 aa) | ||||
| all4265 | ORF_ID:all4265; hypothetical protein. (223 aa) | ||||
| all4272 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (376 aa) | ||||
| all4316 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (369 aa) | ||||
| alr4346 | ORF_ID:alr4346; hypothetical protein. (812 aa) | ||||
| alr4347 | ORF_ID:alr4347; hypothetical protein. (515 aa) | ||||
| all4348 | ORF_ID:all4348; unknown protein. (395 aa) | ||||
| all4349 | ORF_ID:all4349; unknown protein. (399 aa) | ||||
| all4350 | ORF_ID:all4350; unknown protein. (434 aa) | ||||
| alr4351 | Deoxyxylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (399 aa) | ||||
| alr4385 | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa) | ||||
| all4428 | ORF_ID:all4428; hypothetical protein. (411 aa) | ||||
| all4432 | ORF_ID:all4432; probable exopolysaccharide biosynthesis protein. (734 aa) | ||||
| all4442 | ORF_ID:all4442; unknown protein. (552 aa) | ||||
| rfbC-2 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa) | ||||
| rfbD | dTDP-6-deoxy-L-mannose-dehydrogenase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (294 aa) | ||||
| alr4494 | Mannosyltransferase; ORF_ID:alr4494. (355 aa) | ||||
| all4520 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (392 aa) | ||||
| fda | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa) | ||||
| alr4582 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa) | ||||
| alr4596 | Malic enzyme; ORF_ID:alr4596. (463 aa) | ||||
| alr4634 | ORF_ID:alr4634; probable cytosine deaminase. (140 aa) | ||||
| all4665 | ORF_ID:all4665; hypothetical protein. (364 aa) | ||||
| alr4670 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (330 aa) | ||||
| all4671 | ORF_ID:all4671; hypothetical protein. (193 aa) | ||||
| alr4691 | ORF_ID:alr4691; unknown protein. (541 aa) | ||||
| alr4700 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (191 aa) | ||||
| all4708 | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa) | ||||
| alr4714 | ORF_ID:alr4714; unknown protein. (232 aa) | ||||
| all4768 | ORF_ID:all4768; hypothetical protein. (171 aa) | ||||
| all4770 | ORF_ID:all4770; hypothetical protein. (170 aa) | ||||
| alr4784 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (419 aa) | ||||
| alr4795 | ORF_ID:alr4795; hypothetical protein. (157 aa) | ||||
| alr4807 | ORF_ID:alr4807; probable glycosyltransferase. (348 aa) | ||||
| all4826 | dTDP-glucose dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (314 aa) | ||||
| all4828 | GDP-D-mannose dehydratase; ORF_ID:all4828. (273 aa) | ||||
| alr4846 | Stationary phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (265 aa) | ||||
| alr4848 | Riboflavin kinase/FAD synthase; ORF_ID:alr4848; Belongs to the ribF family. (362 aa) | ||||
| all4874 | ORF_ID:all4874; hypothetical protein. (225 aa) | ||||
| all4926 | ORF_ID:all4926; unknown protein. (1273 aa) | ||||
| alr4943 | Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (337 aa) | ||||
| all4998 | N-acetylmuramoyl-L-alanine amidase-related protein; ORF_ID:all4998. (227 aa) | ||||
| all4999 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:all4999. (597 aa) | ||||
| alr5000 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) | ||||
| all5026 | ORF_ID:all5026; hypothetical protein. (493 aa) | ||||
| all5029 | ORF_ID:all5029; hypothetical protein. (157 aa) | ||||
| atpE | ATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (137 aa) | ||||
| atpB | ATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (482 aa) | ||||
| alr5045 | Penicillin-binding protein; ORF_ID:alr5045. (610 aa) | ||||
| alr5065 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation; Belongs to the MurCDEF family. (494 aa) | ||||
| alr5066 | UDP-N-acetylenolpyruvylglucosamine reductase; Cell wall formation. (331 aa) | ||||
| all5073 | ORF_ID:all5073; hypothetical protein. (475 aa) | ||||
| alr5095 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (229 aa) | ||||
| alr5099 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (206 aa) | ||||
| pbpB | Penicillin-binding protein 2; ORF_ID:alr5101. (763 aa) | ||||
| all5120 | ORF_ID:all5120; unknown protein. (654 aa) | ||||
| all5167 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (228 aa) | ||||
| alr5168 | ORF_ID:alr5168; hypothetical protein. (319 aa) | ||||
| all5222 | ORF_ID:all5222; hypothetical protein. (714 aa) | ||||
| alr5226 | ORF_ID:alr5226; unknown protein. (307 aa) | ||||
| alr5243 | ORF_ID:alr5243; unknown protein. (192 aa) | ||||
| alr5275 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa) | ||||
| accA | acetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa) | ||||
| alr5340 | ORF_ID:alr5340; hypothetical protein. (408 aa) | ||||
| all5345 | Oxidoreductase; ORF_ID:all5345. (333 aa) | ||||