STRINGSTRING
leuS leuS gltX gltX all3034 all3034 tyrS tyrS panC panC all2846 all2846 alr2725 alr2725 alr2485 alr2485 alr2483 alr2483 alr2467 alr2467 alr4891 alr4891 alr4848 alr4848 argG argG all4464 all4464 all4242 all4242 alr4700 alr4700 alr2264 alr2264 all1816 all1816 all1590 all1590 all1359 all1359 valS valS alr1286 alr1286 trpS trpS all5138 all5138 alr5095 alr5095 alr4917 alr4917 all5063 all5063 all0233 all0233 all0244 all0244 all0634 all0634 alr0750 alr0750 alr0882 alr0882 all0932 all0932 ileS ileS cysS cysS all1122 all1122 alr4132 alr4132 argS argS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
leuSleucyl-tRNA synthetase; ORF_ID:alr3283; leuS gene product; Belongs to the class-I aminoacyl-tRNA synthetase family. (872 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (480 aa)
all3034ORF_ID:all3034; unknown protein. (234 aa)
tyrSTyrosyl tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (398 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (534 aa)
all2846GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (540 aa)
alr2725Deoxyribopyrimidine photolyase; ORF_ID:alr2725; Belongs to the DNA photolyase family. (479 aa)
alr2485NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (566 aa)
alr2483Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa)
alr2467ORF_ID:alr2467; hypothetical protein. (263 aa)
alr4891ORF_ID:alr4891; probable chloride channel protein. (871 aa)
alr4848Riboflavin kinase/FAD synthase; ORF_ID:alr4848; Belongs to the ribF family. (362 aa)
argGArgininosuccinate synthase; ORF_ID:alr4798; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa)
all4464Phosphoadenosine phosphosulfate reductase; ORF_ID:all4464; Belongs to the PAPS reductase family. CysH subfamily. (241 aa)
all4242Potassium-dependent ATPase subunit D; ORF_ID:all4242. (377 aa)
alr4700Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (191 aa)
alr2264Na+/H+-exchanging protein; ORF_ID:alr2264. (543 aa)
all1816ORF_ID:all1816; hypothetical protein. (215 aa)
all1590ORF_ID:all1590; hypothetical protein. (141 aa)
all1359tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (352 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (1014 aa)
alr1286ORF_ID:alr1286; hypothetical protein. (275 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (335 aa)
all5138Sulfate adenylyltransferase; ORF_ID:all5138; Belongs to the sulfate adenylyltransferase family. (343 aa)
alr50957-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (229 aa)
alr4917ORF_ID:alr4917; unknown protein. (562 aa)
all5063Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (208 aa)
all0233methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (530 aa)
all0244ORF_ID:all0244; hypothetical protein. (174 aa)
all0634ORF_ID:all0634; hypothetical protein. (173 aa)
alr0750ORF_ID:alr0750; hypothetical protein. (180 aa)
alr0882ORF_ID:alr0882; hypothetical protein. (283 aa)
all0932tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (342 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (960 aa)
cysScysteinyl-tRNA synthetase; ORF_ID:all1092; cysS gene product; Belongs to the class-I aminoacyl-tRNA synthetase family. (486 aa)
all1122ORF_ID:all1122; hypothetical protein. (170 aa)
alr4132ORF_ID:alr4132; hypothetical protein. (135 aa)
argSarginyl-tRNA-synthetase; ORF_ID:all3717. (588 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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