STRINGSTRING
hetR hetR devA devA alr3952 alr3952 alr3955 alr3955 ntcA ntcA all4590 all4590 agp agp hepA hepA fdxB fdxB all2367 all2367 moeB moeB glnA glnA alr2205 alr2205 all1893 all1893 all1866 all1866 icd icd nifB nifB nifU nifU hesA hesA hesB hesB fdxH fdxH nifV1 nifV1 all1368 all1368 ccmM ccmM alr0819 alr0819 gltA gltA glgB glgB trxA trxA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hetRHeterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. (299 aa)
devAHeterocyst specific ABC-transporter, ATP-binding subunit; ORF_ID:alr3712; devA gene product. (244 aa)
alr3952Transcriptional regulator; ORF_ID:alr3952. (239 aa)
alr3955Thioredoxin; ORF_ID:alr3955. (128 aa)
ntcANitrogen-responsive regulatory protein; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. (223 aa)
all4590Protease IV; ORF_ID:all4590. (609 aa)
agpGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. (429 aa)
hepAATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. (607 aa)
fdxBFerredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (97 aa)
all2367Thioredoxin; ORF_ID:all2367; Belongs to the thioredoxin family. (108 aa)
moeBMolybdopterin biosynthesis protein; ORF_ID:all2906; moeB gene product. (390 aa)
glnAGlutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (474 aa)
alr2205Thioredoxin; ORF_ID:alr2205; Belongs to the thioredoxin family. (113 aa)
all1893Thioredoxin; ORF_ID:all1893; Belongs to the thioredoxin family. (105 aa)
all1866Thioredoxin; ORF_ID:all1866; Belongs to the thioredoxin family. (110 aa)
icdIsocitrate dehydrogenase; ORF_ID:alr1827; icd gene product. (473 aa)
nifBNitrogen fixation protein; Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster. (475 aa)
nifUNitrogen fixation protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. (300 aa)
hesAHesA protein; May be required for efficient nitrogen fixation. (252 aa)
hesBHesB protein; May be required for efficient nitrogen fixation. (123 aa)
fdxHHeterocyst ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Donates electrons to the nitrogenase. (99 aa)
nifV1Homocitrate synthase; This protein is a Fe-Mo-cofactor biosynthetic component; Belongs to the alpha-IPM synthase/homocitrate synthase family. (377 aa)
all1368Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
ccmMCarbon dioxide concentrating mechanism protein; ORF_ID:all0865; ccmM gene product. (555 aa)
alr0819ORF_ID:alr0819; putative invertase. (483 aa)
gltACitrate synthase; ORF_ID:alr0222; gltA gene product; Belongs to the citrate synthase family. (378 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (764 aa)
trxAThioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. (107 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
Server load: low (12%) [HD]