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dnaK dnaK nifH nifH nifU nifU dnaJ dnaJ dnaK-2 dnaK-2 nifJ nifJ glnB glnB dnaK-3 dnaK-3 dnaJ-2 dnaJ-2 nifJ-2 nifJ-2 dnaK-4 dnaK-4 atpA atpA dnaJ-4 dnaJ-4 alr3561 alr3561 alr3670 alr3670 argS argS rpoA rpoA rpl14 rpl14 rpl4 rpl4 dnaK-5 dnaK-5 dnaJ-5 dnaJ-5 rpl10 rpl10 dnaJ-3 dnaJ-3 atpF atpF alr0735 alr0735 ileS ileS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaKDnaK-type molecular chaperone; ORF_ID:alr1264; dnaK gene product; Belongs to the heat shock protein 70 family. (532 aa)
nifHNitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. (295 aa)
nifUNitrogen fixation protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. (300 aa)
dnaJChaperone protein; ORF_ID:all1488; dnaJ gene product. (315 aa)
dnaK-2DnaK-type molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family. (633 aa)
nifJPyruvate flavodoxin dehydrogenase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. (1187 aa)
glnBNitrogen regulatory protein P-II; ORF_ID:all2319. (112 aa)
dnaK-3DnaK-type molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family. (653 aa)
dnaJ-2DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] (376 aa)
nifJ-2Pyruvate-flavodoxin dehydrogenase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase. (1199 aa)
dnaK-4DnaK-type molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family. (688 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit; Belongs to the ATPase alpha/beta chains family. (506 aa)
dnaJ-4DnaJ protein; ORF_ID:alr2993. (167 aa)
alr3561Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (640 aa)
alr3670Urease alpha subunit; ORF_ID:alr3670; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (568 aa)
argSarginyl-tRNA-synthetase; ORF_ID:all3717. (588 aa)
rpoARNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (315 aa)
rpl1450S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpl450S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (210 aa)
dnaK-5DnaK-type molecular chaperone; ORF_ID:all4477; dnaK gene product; Belongs to the heat shock protein 70 family. (712 aa)
dnaJ-5Chaperone DnaJ protein; ORF_ID:all4643. (333 aa)
rpl1050S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (181 aa)
dnaJ-3DnaJ protein; ORF_ID:alr2991. (333 aa)
atpFATP synthase subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (187 aa)
alr0735Urease accessory protein G; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (200 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (960 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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