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alr0088 alr0088 dnaK-2 dnaK-2 rbcL rbcL dnaJ dnaJ nifD nifD dnaK dnaK glgB glgB nirA nirA all1811 all1811 alr4745 alr4745 dnaJ-5 dnaJ-5 dnaK-5 dnaK-5 alr3937 alr3937 uvrA uvrA clpC clpC groEL-2 groEL-2 alr3402 alr3402 recA recA dnaJ-4 dnaJ-4 dnaJ-3 dnaJ-3 dnaK-4 dnaK-4 dnaJ-2 dnaJ-2 dnaK-3 dnaK-3 alr2336 alr2336 glnA glnA groEL groEL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
alr0088Single-stranded DNA-binding protein; ORF_ID:alr0088. (119 aa)
dnaK-2DnaK-type molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family. (633 aa)
rbcLRibulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (476 aa)
dnaJChaperone protein; ORF_ID:all1488; dnaJ gene product. (315 aa)
nifDNitrogenase molybdenum-iron protein alpha chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. (497 aa)
dnaKDnaK-type molecular chaperone; ORF_ID:alr1264; dnaK gene product; Belongs to the heat shock protein 70 family. (532 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (764 aa)
nirANitrite reductase; ORF_ID:alr0607; nirA gene product; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (536 aa)
all1811Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (500 aa)
alr4745Dihydrolipoamide dehydrogenase; ORF_ID:alr4745. (475 aa)
dnaJ-5Chaperone DnaJ protein; ORF_ID:all4643. (333 aa)
dnaK-5DnaK-type molecular chaperone; ORF_ID:all4477; dnaK gene product; Belongs to the heat shock protein 70 family. (712 aa)
alr3937Mercuric reductase; ORF_ID:alr3937. (489 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (961 aa)
clpCATP-dependent Clp protease regulatory subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (445 aa)
groEL-2Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (544 aa)
alr3402Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (117 aa)
recARecombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (357 aa)
dnaJ-4DnaJ protein; ORF_ID:alr2993. (167 aa)
dnaJ-3DnaJ protein; ORF_ID:alr2991. (333 aa)
dnaK-4DnaK-type molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family. (688 aa)
dnaJ-2DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] (376 aa)
dnaK-3DnaK-type molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family. (653 aa)
alr2336Phosphate permease; ORF_ID:alr2336. (432 aa)
glnAGlutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (474 aa)
groELChaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (560 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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