STRINGSTRING
alr3297 alr3297 all0070 all0070 chlP chlP alr0140 alr0140 petE petE alr0599 alr0599 petC petC nirA nirA nrtA nrtA alr0652 alr0652 rbpA1 rbpA1 psbW psbW ccmM ccmM ccmK-3 ccmK-3 alr1299 alr1299 alr1346 alr1346 all1361 all1361 all1411 all1411 nifD nifD nifH nifH petC-2 petC-2 rbcL rbcL rpoB rpoB rpoC1 rpoC1 all1683 all1683 icd icd alr1900 alr1900 all1939 all1939 all2070 all2070 rbpF rbpF all2318 all2318 glnB glnB glnA glnA hetR hetR all2375 all2375 alr2418 alr2418 alr2440 alr2440 petC-3 petC-3 lepA lepA alr2535 alr2535 alr2765 alr2765 rbpE rbpE hepA hepA alr2889 alr2889 rbpB rbpB lrtA lrtA gltX gltX all3255 all3255 asr3294 asr3294 alr3393 alr3393 nodM nodM thiG thiG all3556 all3556 alr3670 alr3670 fbp fbp rbpD rbpD thrA thrA all4131 all4131 secY secY alr4232 alr4232 tufA tufA all4377 all4377 alr4380 alr4380 ntcA ntcA alr4404 alr4404 alr4505 alr4505 petC-4 petC-4 asl4547 asl4547 alr4566 alr4566 alr4641 alr4641 all4662 all4662 rbpD-2 rbpD-2 patN patN alr4853 alr4853 ftsH-4 ftsH-4 gor gor alr5103 alr5103 psaA psaA psaB psaB alr5275 alr5275 secE secE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
alr3297ORF_ID:alr3297; hypothetical protein. (209 aa)
all0070Superoxide dismutase; ORF_ID:all0070. (270 aa)
chlPGeranylgeranyl hydrogenase; ORF_ID:alr0128; chlP gene product. (406 aa)
alr0140Periplasmic oligopeptide-binding protein of oligopeptide ABC transporter; ORF_ID:alr0140. (552 aa)
petEPlastocyanin precursor; Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I. (139 aa)
alr05991-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (635 aa)
petCCytochrome b6/f-complex iron-sulfur protein; ORF_ID:all0606; petC gene product. (136 aa)
nirANitrite reductase; ORF_ID:alr0607; nirA gene product; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (536 aa)
nrtANitrate transport nitrate-binding protein; Part of the ABC transporter complex NrtABCD involved in nitrate uptake. The complex is probably also involved in nitrite transport. NrtA is the substrate-binding protein. (440 aa)
alr0652Iron-sulfur cluster carrier protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (356 aa)
rbpA1RNA-binding protein; ORF_ID:alr0741; rbpA1 gene product. (102 aa)
psbWPhotosystem II protein W; ORF_ID:all0801; Belongs to the Psb28 family. (111 aa)
ccmMCarbon dioxide concentrating mechanism protein; ORF_ID:all0865; ccmM gene product. (555 aa)
ccmK-3Carbon dioxide concentrating mechanism protein; ORF_ID:all0867; ccmK gene product. (114 aa)
alr1299Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (391 aa)
alr1346ORF_ID:alr1346; hypothetical protein. (327 aa)
all1361ORF_ID:all1361; similar to cytochrome P450. (517 aa)
all1411ORF_ID:all1411; unknown protein. (123 aa)
nifDNitrogenase molybdenum-iron protein alpha chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. (497 aa)
nifHNitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. (295 aa)
petC-2Cytochrome b6/f-complex iron-sulfur protein; Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. Belongs to the Rieske iron-sulfur protein family. (178 aa)
rbcLRibulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (476 aa)
rpoBRNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1131 aa)
rpoC1RNA polymerase gamma subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (625 aa)
all1683Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (392 aa)
icdIsocitrate dehydrogenase; ORF_ID:alr1827; icd gene product. (473 aa)
alr1900Phosphoglucomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (494 aa)
all1939Processing proteinase; ORF_ID:all1939. (512 aa)
all2070ORF_ID:all2070; hypothetical protein. (301 aa)
rbpFRNA-binding protein; ORF_ID:alr2311; rbpF gene product. (105 aa)
all2318ORF_ID:all2318; hypothetical protein. (264 aa)
glnBNitrogen regulatory protein P-II; ORF_ID:all2319. (112 aa)
glnAGlutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (474 aa)
hetRHeterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. (299 aa)
all2375ORF_ID:all2375; similar to bacterioferritin comigratory protein. (145 aa)
alr2418alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (880 aa)
alr2440ORF_ID:alr2440; hypothetical protein. (334 aa)
petC-3Plastoquinol--plastocyanin reductase; Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. Belongs to the Rieske iron-sulfur protein family. (179 aa)
lepAGTP-binding elongation factor; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (603 aa)
alr2535Branched-chain amino-acid ABC transport system periplasmic binding protein; ORF_ID:alr2535. (268 aa)
alr2765Aminotransferase; ORF_ID:alr2765. (403 aa)
rbpERNA binding protein; ORF_ID:all2777; rbpE gene product. (99 aa)
hepAATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. (607 aa)
alr2889ORF_ID:alr2889; hypothetical protein. (168 aa)
rbpBRNA-binding protein; ORF_ID:all2928; rbpB gene product. (103 aa)
lrtALight-repressed protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (213 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (480 aa)
all3255Transport protein; ORF_ID:all3255. (220 aa)
asr3294ORF_ID:asr3294; hypothetical protein. (91 aa)
alr3393ORF_ID:alr3393; similar to serum-resistance protein BrkB. (314 aa)
nodMglutamine-fructose-6-P-aminotransferase; ORF_ID:alr3464; nodM gene product. (541 aa)
thiGThiamin biosynthesis protein; Catalyzes the FAD-dependent oxidative deamination of glycine. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate; In the N-terminal section; belongs to the DAO family. ThiO subfamily. (652 aa)
all3556Succinate-semialdehyde dehydrogenase; ORF_ID:all3556. (455 aa)
alr3670Urease alpha subunit; ORF_ID:alr3670; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (568 aa)
fbpFructose 1,6-bisphosphatase; ORF_ID:all4021. (349 aa)
rbpDRNA-binding protein; ORF_ID:asl4022. (94 aa)
thrAHomoserine dehydrogenase; ORF_ID:all4120. (429 aa)
all4131Phosphoglycerate kinase; ORF_ID:all4131. (400 aa)
secYPreprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (437 aa)
alr4232Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (503 aa)
tufATranslation elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (409 aa)
all4377RNA-binding protein; ORF_ID:all4377. (166 aa)
alr4380Delta-aminolevulinic acid dehydratase; ORF_ID:alr4380; Belongs to the ALAD family. (326 aa)
ntcANitrogen-responsive regulatory protein; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. (223 aa)
alr4404AhpC/TSA family protein; ORF_ID:alr4404. (212 aa)
alr4505ORF_ID:alr4505; unknown protein. (359 aa)
petC-4Cytochrome b6/f-complex iron-sulfur protein; Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. Belongs to the Rieske iron-sulfur protein family. (178 aa)
asl4547ORF_ID:asl4547; hypothetical protein; Belongs to the UPF0367 family. (90 aa)
alr4566NADH-dependent butanol dehydrogenase; ORF_ID:alr4566. (384 aa)
alr4641Peroxiredoxin; ORF_ID:alr4641. (203 aa)
all4662ORF_ID:all4662; hypothetical protein; Belongs to the UPF0234 family. (163 aa)
rbpD-2RNA-binding protein; ORF_ID:alr4683; rbpD gene product. (110 aa)
patNHeterocyst differentiation related protein; ORF_ID:alr4812; patN gene product. (215 aa)
alr4853Aspartate aminotransferase; ORF_ID:alr4853. (388 aa)
ftsH-4Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (645 aa)
gorGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (459 aa)
alr5103Aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (411 aa)
psaAPhotosystem I core protein A1; PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6. (752 aa)
psaBPhotosystem I core protein A2; PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6 (By similarity). (741 aa)
alr52756-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa)
secESecretory protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (73 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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