STRINGSTRING
alr3338 alr3338 trxA trxA all0089 all0089 psbB psbB alr0237 alr0237 psbV psbV all0268 all0268 trpG trpG alr0517 alr0517 cpcB cpcB cpcG4 cpcG4 alr0540 alr0540 ntcB ntcB nrtA nrtA ccmN ccmN ccmM ccmM ccmL ccmL ccmK-4 ccmK-4 alr1004 alr1004 gap3 gap3 asr1156 asr1156 all1338 all1338 all1361 all1361 all1411 all1411 nifH nifH rbcL rbcL rbcS rbcS rca rca alr1554 alr1554 all1683 all1683 all1866 all1866 all2316 all2316 glnB glnB apcF apcF glnA glnA hetR hetR all2341 all2341 all2367 all2367 alr2418 alr2418 all2521 all2521 gap1 gap1 alr2758 alr2758 alr2765 alr2765 alr2811 alr2811 hetP hetP hepA hepA all2846 all2846 cmpA cmpA dnaJ-3 dnaJ-3 gltX gltX all3255 all3255 recA recA nodM nodM ppa ppa alr3670 alr3670 clpP-2 clpP-2 alr3871 alr3871 asr3935 asr3935 alr3955 alr3955 rbpD rbpD rps13 rps13 cytA cytA psaE psaE gltS gltS asl4369 asl4369 ntcA ntcA alr4505 alr4505 all4580 all4580 ilvG ilvG rbpD-2 rbpD-2 argG argG alr4806 alr4806 alr4831 alr4831 alr4853 alr4853 alr4907 alr4907 gor gor atpB atpB alr5103 alr5103
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
alr3338Phosphoglycerate mutase; ORF_ID:alr3338; Belongs to the phosphoglycerate mutase family. (449 aa)
trxAThioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. (107 aa)
all0089ORF_ID:all0089; hypothetical protein. (221 aa)
psbBPhotosystem II CP47 protein; One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light- induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation; Belongs to the PsbB/PsbC family. PsbB subfamily. (509 aa)
alr0237Leucine aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (491 aa)
psbVCytochrome c550; Low-potential cytochrome c that plays a role in the oxygen- evolving complex of photosystem II. (163 aa)
all0268ORF_ID:all0268; hypothetical protein. (255 aa)
trpGAnthranilate synthase component II; ORF_ID:all0269; trpG gene product. (184 aa)
alr0517Fructokinase; ORF_ID:alr0517. (325 aa)
cpcBPhycocyanin beta chain; Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex. (173 aa)
cpcG4Phycobilisome rod-core linker protein; Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes. (253 aa)
alr05401-pyrroline-5 carboxylate dehydrogenase; ORF_ID:alr0540; Belongs to the aldehyde dehydrogenase family. (996 aa)
ntcBNitrogen assimilation transcriptional activator; ORF_ID:all0602; ntcB gene product; Belongs to the LysR transcriptional regulatory family. (312 aa)
nrtANitrate transport nitrate-binding protein; Part of the ABC transporter complex NrtABCD involved in nitrate uptake. The complex is probably also involved in nitrite transport. NrtA is the substrate-binding protein. (440 aa)
ccmNCarbon dioxide concentrating mechanism protein; ORF_ID:all0864; ccmN gene product. (248 aa)
ccmMCarbon dioxide concentrating mechanism protein; ORF_ID:all0865; ccmM gene product. (555 aa)
ccmLCarbon dioxide concentrating mechanism protein; ORF_ID:all0866; ccmL gene product. (101 aa)
ccmK-4Carbon dioxide concentrating mechanism protein; ORF_ID:all0868; ccmK gene product. (102 aa)
alr1004Alanine--glyoxylate aminotransferase; ORF_ID:alr1004. (381 aa)
gap3Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG; Belongs to the glyceraldehyde-3-phosphate dehydrogenase [...] (337 aa)
asr1156ORF_ID:asr1156; hypothetical protein. (70 aa)
all1338ORF_ID:all1338; hypothetical protein. (423 aa)
all1361ORF_ID:all1361; similar to cytochrome P450. (517 aa)
all1411ORF_ID:all1411; unknown protein. (123 aa)
nifHNitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. (295 aa)
rbcLRibulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (476 aa)
rbcSRibulose 1,5-bisphosphate carboxylase/oxygenase small subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site (By similarity); Belongs to the RuBisCO small chain family. (109 aa)
rcaRibulose 1,5-bisphosphate carboxylase/oxygenase activase; Activation of RuBisCO (ribulose-1,5-bisohosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure. (414 aa)
alr1554ABC transporter ATP-binding protein; ORF_ID:alr1554. (608 aa)
all1683Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (392 aa)
all1866Thioredoxin; ORF_ID:all1866; Belongs to the thioredoxin family. (110 aa)
all2316Aldo/keto reductase; ORF_ID:all2316. (284 aa)
glnBNitrogen regulatory protein P-II; ORF_ID:all2319. (112 aa)
apcFPhycobilisome core component; A variant beta-allophycocyanin (AP) which forms a complex with ApcE, a phycobilisome terminal emitter that influences energy transfer to photosystem II; Belongs to the phycobiliprotein family. (169 aa)
glnAGlutamate--ammonia ligase; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (474 aa)
hetRHeterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. (299 aa)
all2341Thioredoxin 2; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. (115 aa)
all2367Thioredoxin; ORF_ID:all2367; Belongs to the thioredoxin family. (108 aa)
alr2418alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (880 aa)
all2521Cysteine synthase; ORF_ID:all2521; Belongs to the cysteine synthase/cystathionine beta- synthase family. (319 aa)
gap1Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. (343 aa)
alr2758Serine proteinase; ORF_ID:alr2758. (407 aa)
alr2765Aminotransferase; ORF_ID:alr2765. (403 aa)
alr2811Valine-pyruvate aminotransferase; ORF_ID:alr2811. (450 aa)
hetPHeterocyst differentiation protein; ORF_ID:alr2818; hetP gene product. (159 aa)
hepAATP-binding protein; Acts early in the process of morphological differentiation of heterocysts. (607 aa)
all2846GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (540 aa)
cmpABicarbonate transport bicarbonate-binding protein; ORF_ID:alr2877; cmpA gene product. (458 aa)
dnaJ-3DnaJ protein; ORF_ID:alr2991. (333 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (480 aa)
all3255Transport protein; ORF_ID:all3255. (220 aa)
recARecombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (357 aa)
nodMglutamine-fructose-6-P-aminotransferase; ORF_ID:alr3464; nodM gene product. (541 aa)
ppaInorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions; Belongs to the PPase family. (169 aa)
alr3670Urease alpha subunit; ORF_ID:alr3670; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (568 aa)
clpP-2ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (232 aa)
alr38714-alpha-glucanotransferase; ORF_ID:alr3871. (502 aa)
asr3935DNA binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. It is essential for heterocyst differentiation; Belongs to the bacterial histone-like protein family. (94 aa)
alr3955Thioredoxin; ORF_ID:alr3955. (128 aa)
rbpDRNA-binding protein; ORF_ID:asl4022. (94 aa)
rps1330S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (126 aa)
cytACytochrome c6; Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis. (111 aa)
psaEPhotosystem I protein E; Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase; Belongs to the PsaE family. (70 aa)
gltSFerredoxin-glutamate synthase; ORF_ID:alr4344. (1559 aa)
asl4369ORF_ID:asl4369; hypothetical protein. (94 aa)
ntcANitrogen-responsive regulatory protein; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. (223 aa)
alr4505ORF_ID:alr4505; unknown protein. (359 aa)
all4580ORF_ID:all4580; unknown protein. (358 aa)
ilvGAcetohydroxy acid synthase; ORF_ID:all4613; ilvG gene product. (632 aa)
rbpD-2RNA-binding protein; ORF_ID:alr4683; rbpD gene product. (110 aa)
argGArgininosuccinate synthase; ORF_ID:alr4798; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa)
alr4806Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
alr4831mRNA-binding protein; ORF_ID:alr4831. (311 aa)
alr4853Aspartate aminotransferase; ORF_ID:alr4853. (388 aa)
alr4907Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (306 aa)
gorGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (459 aa)
atpBATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (482 aa)
alr5103Aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (411 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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