node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alr5272 | kaiC | gene:10497331 | gene:10494920 | Two-component sensor histidine kinase; ORF_ID:alr5272. | Circadian oscillation regulator; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.474 |
alr5272 | rpaA | gene:10497331 | gene:10492134 | Two-component sensor histidine kinase; ORF_ID:alr5272. | Two-component response regulator; ORF_ID:all0129; rpaA gene product. | 0.477 |
hetN | hetR | gene:10497420 | gene:10494368 | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | 0.916 |
hetN | patS | gene:10497420 | gene:10494330 | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | Heterocyst-inhibiting signaling peptide; Inhibits heterocyst differentiation. Seems to control heterocyst pattern formation through intercellular signaling mechanisms. In Anabaena filaments every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation. Seems to inhibit the formation of adjacent heterocysts. Inhibits the DNA-binding of HetR. | 0.916 |
hetR | hetN | gene:10494368 | gene:10497420 | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | Ketoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. | 0.916 |
hetR | patS | gene:10494368 | gene:10494330 | Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. | Heterocyst-inhibiting signaling peptide; Inhibits heterocyst differentiation. Seems to control heterocyst pattern formation through intercellular signaling mechanisms. In Anabaena filaments every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation. Seems to inhibit the formation of adjacent heterocysts. Inhibits the DNA-binding of HetR. | 0.916 |
kaiA | kaiB | gene:10494918 | gene:10494919 | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC [...] | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity); Belongs to the KaiB family. | 0.998 |
kaiA | kaiB-2 | gene:10494918 | gene:10495366 | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC [...] | Circadian oscillation regulator; ORF_ID:all3328; kaiB gene product. | 0.991 |
kaiA | kaiC | gene:10494918 | gene:10494920 | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC [...] | Circadian oscillation regulator; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.998 |
kaiA | pecB | gene:10494918 | gene:10492534 | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC [...] | Phycoerythrocyanin beta chain; Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex. | 0.443 |
kaiB | kaiA | gene:10494919 | gene:10494918 | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity); Belongs to the KaiB family. | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC [...] | 0.998 |
kaiB | kaiC | gene:10494919 | gene:10494920 | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity); Belongs to the KaiB family. | Circadian oscillation regulator; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.999 |
kaiB | pecB | gene:10494919 | gene:10492534 | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity); Belongs to the KaiB family. | Phycoerythrocyanin beta chain; Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex. | 0.456 |
kaiB | rpaA | gene:10494919 | gene:10492134 | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity); Belongs to the KaiB family. | Two-component response regulator; ORF_ID:all0129; rpaA gene product. | 0.455 |
kaiB-2 | kaiA | gene:10495366 | gene:10494918 | Circadian oscillation regulator; ORF_ID:all3328; kaiB gene product. | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC [...] | 0.991 |
kaiB-2 | kaiC | gene:10495366 | gene:10494920 | Circadian oscillation regulator; ORF_ID:all3328; kaiB gene product. | Circadian oscillation regulator; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.997 |
kaiC | alr5272 | gene:10494920 | gene:10497331 | Circadian oscillation regulator; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | Two-component sensor histidine kinase; ORF_ID:alr5272. | 0.474 |
kaiC | kaiA | gene:10494920 | gene:10494918 | Circadian oscillation regulator; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC [...] | 0.998 |
kaiC | kaiB | gene:10494920 | gene:10494919 | Circadian oscillation regulator; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | Circadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity); Belongs to the KaiB family. | 0.999 |
kaiC | kaiB-2 | gene:10494920 | gene:10495366 | Circadian oscillation regulator; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | Circadian oscillation regulator; ORF_ID:all3328; kaiB gene product. | 0.997 |