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kaiA kaiA rpaA rpaA pecB pecB alr0957 alr0957 patS patS alr2325 alr2325 hetR hetR kaiB kaiB kaiC kaiC kaiB-2 kaiB-2 alr3646 alr3646 ycf27 ycf27 alr5272 alr5272 hetN hetN
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
kaiACircadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC [...] (102 aa)
rpaATwo-component response regulator; ORF_ID:all0129; rpaA gene product. (247 aa)
pecBPhycoerythrocyanin beta chain; Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex. (172 aa)
alr0957Ferric uptake regulator; ORF_ID:alr0957; Belongs to the Fur family. (149 aa)
patSHeterocyst-inhibiting signaling peptide; Inhibits heterocyst differentiation. Seems to control heterocyst pattern formation through intercellular signaling mechanisms. In Anabaena filaments every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation. Seems to inhibit the formation of adjacent heterocysts. Inhibits the DNA-binding of HetR. (17 aa)
alr2325Transcriptional regulator; ORF_ID:alr2325. (227 aa)
hetRHeterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS. (299 aa)
kaiBCircadian oscillation regulator; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity); Belongs to the KaiB family. (108 aa)
kaiCCircadian oscillation regulator; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. (519 aa)
kaiB-2Circadian oscillation regulator; ORF_ID:all3328; kaiB gene product. (254 aa)
alr3646Transcriptional regulator; ORF_ID:alr3646. (200 aa)
ycf27Two-component response regulator; ORF_ID:all3822. (242 aa)
alr5272Two-component sensor histidine kinase; ORF_ID:alr5272. (751 aa)
hetNKetoacyl reductase; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. (287 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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