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all0122 all0122 all0635 all0635 all0879 all0879 alr1041 alr1041 alr1050 alr1050 gap3 gap3 all1371 all1371 nifJ nifJ alr1913 alr1913 alr1982 alr1982 all2509 all2509 all2564 all2564 gap1 gap1 alr2708 alr2708 nifJ-2 nifJ-2 all2810 all2810 alr2973 alr2973 alr3146 alr3146 alr3147 alr3147 alr3397 alr3397 all3538 all3538 alr3606 alr3606 alr3672 alr3672 all3735 all3735 alr3937 alr3937 all4008 all4008 fbp fbp all4131 all4131 all4182 all4182 all4237 all4237 all4257 all4257 alr4385 alr4385 fda fda alr4745 alr4745 all5002 all5002 gap2 gap2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
all0122Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
all0635Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (821 aa)
all0879Alcohol dehydrogenase; ORF_ID:all0879. (328 aa)
alr1041Fructose-1,6-bisphosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. (345 aa)
alr1050Glucose-6-phosphate isomerase; ORF_ID:alr1050. (528 aa)
gap3Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG; Belongs to the glyceraldehyde-3-phosphate dehydrogenase [...] (337 aa)
all1371Polyphosphate glucokinase; ORF_ID:all1371. (239 aa)
nifJPyruvate flavodoxin dehydrogenase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. (1187 aa)
alr19136-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (357 aa)
alr1982ORF_ID:alr1982; putative sugar kinase. (317 aa)
all2509ORF_ID:all2509; similar to phosphoenolpyruvate synthase. (963 aa)
all2564Pyruvate kinase; ORF_ID:all2564; Belongs to the pyruvate kinase family. (476 aa)
gap1Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. (343 aa)
alr2708Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa)
nifJ-2Pyruvate-flavodoxin dehydrogenase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase. (1199 aa)
all2810Glutathione dependent formaldehyde dehydrogenase; ORF_ID:all2810; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
alr2973Glucokinase; ORF_ID:alr2973; Belongs to the bacterial glucokinase family. (342 aa)
alr3146Phosphoenolpyruvate synthase; ORF_ID:alr3146. (643 aa)
alr3147Phosphoenolpyruvate synthase; ORF_ID:alr3147. (163 aa)
alr3397Phosphoenolpyruvate synthase; ORF_ID:alr3397. (775 aa)
all3538Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
alr3606Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. (430 aa)
alr3672Aldehyde dehydrogenase; ORF_ID:alr3672; Belongs to the aldehyde dehydrogenase family. (460 aa)
all3735Fructose-bisphosphate aldolase class I; ORF_ID:all3735. (360 aa)
alr3937Mercuric reductase; ORF_ID:alr3937. (489 aa)
all4008Pyruvate kinase; ORF_ID:all4008; Belongs to the pyruvate kinase family. (589 aa)
fbpFructose 1,6-bisphosphatase; ORF_ID:all4021. (349 aa)
all4131Phosphoglycerate kinase; ORF_ID:all4131. (400 aa)
all41822,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (533 aa)
all4237ORF_ID:all4237; hypothetical protein. (100 aa)
all4257Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (524 aa)
alr4385Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa)
fdaFructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa)
alr4745Dihydrolipoamide dehydrogenase; ORF_ID:alr4745. (475 aa)
all5002Sugar kinase; ORF_ID:all5002. (311 aa)
gap2Glyceraldehyde-3-phosphate dehydrogenase; Gap2 has a major role in carbon fixation as a component of the Calvin cycle. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NADP. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NADP to NADPH. The reduced NADPH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic p [...] (337 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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