STRINGSTRING
all0032 all0032 menA menA menC menC menE menE all0245 all0245 menD menD all0419 all0419 all0771 all0771 all0938 all0938 alr1108 alr1108 alr1241 alr1241 alr1803 alr1803 all2121 all2121 all2347 all2347 alr2465 alr2465 all2598 all2598 all2753 all2753 alr3448 alr3448 alr3553 alr3553 alr4094 alr4094 ubiH ubiH alr5252 alr5252
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
all0032Isochorismate synthase; ORF_ID:all0032. (471 aa)
menADHNA phythltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily. (309 aa)
menCO-succinylbenzoic acid synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (320 aa)
menEO-succinylbenzoyl-CoA synthetase; ORF_ID:alr0035; menE gene product. (483 aa)
all0245ORF_ID:all0245; hypothetical protein. (363 aa)
menD2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (587 aa)
all0419ORF_ID:all0419; hypothetical protein. (303 aa)
all07714-hydroxyphenylpyruvate dioxygenase; ORF_ID:all0771. (344 aa)
all0938ORF_ID:all0938; hypothetical protein. (137 aa)
alr1108ORF_ID:alr1108; hypothetical protein; Belongs to the UbiD family. (502 aa)
alr12413-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (209 aa)
alr1803Gamma-tocopherol methyltransferase; ORF_ID:alr1803; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. (280 aa)
all2121ORF_ID:all2121; probable delta(24)-sterol C-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. (330 aa)
all2347Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (277 aa)
alr24651,4-dihydroxy-2-naphthoyl-CoA hydrolase; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis; Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily. (148 aa)
all2598ORF_ID:all2598; hypothetical protein. (284 aa)
all2753Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC); Belongs to the AB hydrolase superfamily. MenH family. (273 aa)
alr3448ORF_ID:alr3448; hypothetical protein. (318 aa)
alr35534-hydroxybenzoate-octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of plastoquinone-9 (PQ-9) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 4-hydroxy-3-solanesylbenzoate. Belongs to the UbiA prenyltransferase family. (290 aa)
alr4094NADH dehydrogenase; ORF_ID:alr4094. (409 aa)
ubiHUbiH protein; ORF_ID:all4274; probable 2-octaprenyl-6-methoxyphenol 4-monoxygenase; UbiH. (419 aa)
alr52522-phytyl-1,4-naphtoquinone methyltransferase; Methyltransferase required for the conversion of 2-phytyl- 1,4-beta-naphthoquinol to phylloquinol. (229 aa)
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
Server load: low (20%) [HD]