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apt | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (180 aa) | ||||
pyrR | Unannotated protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (194 aa) | ||||
pyrB | Unannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (322 aa) | ||||
pyrC | Unannotated protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (430 aa) | ||||
MCOL_V219386 | Unannotated protein. (167 aa) | ||||
carA | Unannotated protein; Belongs to the CarA family. (373 aa) | ||||
carB | Unannotated protein; Belongs to the CarB family. (1116 aa) | ||||
pyrF | Unannotated protein; Belongs to the OMP decarboxylase family. Type 2 subfamily. (274 aa) | ||||
gmk | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. (201 aa) | ||||
gcvH | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (132 aa) | ||||
gcvP | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (942 aa) | ||||
MCOL_V209400 | Unannotated protein. (478 aa) | ||||
pyrD | Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (368 aa) | ||||
gcvT | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. (371 aa) | ||||
glyA | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa) | ||||
MCOL_V225082 | Unannotated protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (199 aa) | ||||
purH | Unannotated protein. (527 aa) | ||||
purN | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (215 aa) | ||||
purM | Unannotated protein. (364 aa) | ||||
purF | Unannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (508 aa) | ||||
purL | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (765 aa) | ||||
purQ | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (224 aa) | ||||
purS | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (79 aa) | ||||
purC | Unannotated protein; Belongs to the SAICAR synthetase family. (296 aa) | ||||
MCOL_V213560 | Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (472 aa) | ||||
purD | Unannotated protein; Belongs to the GARS family. (422 aa) | ||||
MCOL_V201615 | Unannotated protein; Belongs to the globin family. (393 aa) | ||||
MCOL_V201600 | Unannotated protein. (292 aa) | ||||
pyrE | Unannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (179 aa) | ||||
purA | Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa) | ||||
purT | Unannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. (418 aa) | ||||
guaB | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (531 aa) | ||||
MCOL_V216174 | Unannotated protein. (375 aa) | ||||
guaA | Unannotated protein; Catalyzes the synthesis of GMP from XMP. (530 aa) | ||||
folD | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (281 aa) | ||||
purK | Unannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (405 aa) | ||||
GCA_002105755_04980 | Unannotated protein. (88 aa) | ||||
purE | Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (95 aa) |