STRINGSTRING
BAK46059.1 BAK46059.1 BAK46108.1 BAK46108.1 BAK46319.1 BAK46319.1 fabZ fabZ FabB FabB BAK46322.1 BAK46322.1 BAK46323.1 BAK46323.1 BAK46324.1 BAK46324.1 fabH fabH AcpP AcpP BAK46331.1 BAK46331.1 mprF mprF BAK46574.1 BAK46574.1 EutG-2 EutG-2 MdlB-2 MdlB-2 BAK46577.1 BAK46577.1 BAK46578.1 BAK46578.1 BAK46579.1 BAK46579.1 BAK46580.1 BAK46580.1 OppA OppA BAK46582.1 BAK46582.1 BAK46583.1 BAK46583.1 UgpQ-2 UgpQ-2 BAK46588.1 BAK46588.1 BAK46589.1 BAK46589.1 GrsT GrsT BAK46591.1 BAK46591.1 PutP-4 PutP-4 BAK46593.1 BAK46593.1 EntF EntF BAK46595.1 BAK46595.1 DltB DltB FcbC FcbC Uup Uup BAK46834.1 BAK46834.1 BAK47536.1 BAK47536.1 BAK47537.1 BAK47537.1 AcpP-2 AcpP-2 BAK47539.1 BAK47539.1 dltA dltA OmpR-4 OmpR-4 BaeS-4 BaeS-4 BAK47552.1 BAK47552.1 acpP acpP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BAK46059.1Hypothetical protein. (268 aa)
BAK46108.1Hypothetical protein. (322 aa)
BAK46319.1Hypothetical protein. (172 aa)
fabZHypothetical protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (144 aa)
FabB3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (418 aa)
BAK46322.1Hypothetical protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
BAK46323.1Hypothetical protein. (308 aa)
BAK46324.1Hypothetical protein. (309 aa)
fabHHypothetical protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (314 aa)
AcpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa)
BAK46331.1Hypothetical protein. (292 aa)
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (353 aa)
BAK46574.1Hypothetical protein. (308 aa)
EutG-2Alcohol dehydrogenase IV. (393 aa)
MdlB-2ABC-type multidrug/protein/lipid transport system, ATPase component. (56 aa)
BAK46577.1Hypothetical protein; Belongs to the aldehyde dehydrogenase family. (506 aa)
BAK46578.1Hypothetical protein. (300 aa)
BAK46579.1Hypothetical protein. (338 aa)
BAK46580.1ATPase component of various ABC-type transport system; Contain duplicated ATPase; Belongs to the ABC transporter superfamily. (679 aa)
OppAABC-type dipeptide/oligopeptide/nickel transport system; Periplasmic component. (527 aa)
BAK46582.1Hypothetical protein. (141 aa)
BAK46583.1Uncharacterized BCR. (108 aa)
UgpQ-2Glycerophosphoryl diester phosphodiesterase. (281 aa)
BAK46588.1Hypothetical protein. (222 aa)
BAK46589.1Hypothetical protein. (307 aa)
GrsTPredicted thioesterase involved in non-ribosomal peptide biosynthesis. (243 aa)
BAK46591.1Hypothetical protein. (75 aa)
PutP-4Na+/proline, Na+/panthothenate symporter; Related permease; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (531 aa)
BAK46593.1Hypothetical protein. (40 aa)
EntFNon-ribosomal peptide synthetase modules; Related protein. (508 aa)
BAK46595.1Hypothetical protein. (449 aa)
DltBPredicted membrane protein involved in D-alanine export; Belongs to the membrane-bound acyltransferase family. (533 aa)
FcbCPredicted thioesterase. (154 aa)
UupATPase component of ABC transporter with duplicated ATPase domains. (473 aa)
BAK46834.1Hypothetical protein. (68 aa)
BAK47536.1Hypothetical protein. (91 aa)
BAK47537.1Hypothetical protein. (391 aa)
AcpP-2Acyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. (77 aa)
BAK47539.1Hypothetical protein; Could be involved in the transport of activated D-alanine through the membrane. (393 aa)
dltAHypothetical protein; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP-bindin [...] (501 aa)
OmpR-4Response regulator consisting of a CheY-like receiver domain; Winged-helix DNA-binding domain. (237 aa)
BaeS-4Signal transduction histidine kinase. (438 aa)
BAK47552.1Hypothetical protein. (244 aa)
acpPHypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (75 aa)
Your Current Organism:
Clostridium sp. SY8519
NCBI taxonomy Id: 1042156
Other names: C. sp. SY8519
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