STRINGSTRING
AmiC AmiC BAK46010.1 BAK46010.1 murE murE BAK46187.1 BAK46187.1 BAK46191.1 BAK46191.1 ftsZ ftsZ BAK46220.1 BAK46220.1 FtsW FtsW murD murD Rfe Rfe BAK46224.1 BAK46224.1 FtsX FtsX rsmH rsmH mraZ mraZ BAK46231.1 BAK46231.1 ProA ProA BAK46289.1 BAK46289.1 BAK46338.1 BAK46338.1 BAK46481.1 BAK46481.1 BAK46493.1 BAK46493.1 BAK46494.1 BAK46494.1 BAK46497.1 BAK46497.1 ProC ProC BAK46721.1 BAK46721.1 murG murG BAK46732.1 BAK46732.1 BAK46733.1 BAK46733.1 NUC1 NUC1 PolC PolC BAK46738.1 BAK46738.1 BAK46739.1 BAK46739.1 BAK46740.1 BAK46740.1 irB11 irB11 BAK46790.1 BAK46790.1 GcvP GcvP SpoVK SpoVK BAK46824.1 BAK46824.1 BAK46825.1 BAK46825.1 SUA5 SUA5 BAK46827.1 BAK46827.1 BAK46828.1 BAK46828.1 BAK46829.1 BAK46829.1 BAK46831.1 BAK46831.1 BAK46852.1 BAK46852.1 BAK46854.1 BAK46854.1 minC minC BAK46860.1 BAK46860.1 murF murF DdlA-2 DdlA-2 BAK46888.1 BAK46888.1 BAK46889.1 BAK46889.1 BAK46911.1 BAK46911.1 BAK46937.1 BAK46937.1 Soj Soj BAK46939.1 BAK46939.1 BAK46940.1 BAK46940.1 BAK46941.1 BAK46941.1 HipB-3 HipB-3 BAK47075.1 BAK47075.1 BAK47076.1 BAK47076.1 BAK47077.1 BAK47077.1 BAK47100.1 BAK47100.1 BAK47125.1 BAK47125.1 BAK47129.1 BAK47129.1 BAK47130.1 BAK47130.1 murC murC murA murA PcnB PcnB BAK47149.1 BAK47149.1 BAK47275.1 BAK47275.1 BAK47279.1 BAK47279.1 murB murB BAK47295.1 BAK47295.1 WecG WecG BAK47297.1 BAK47297.1 ftsE ftsE FtsX-2 FtsX-2 BAK47349.1 BAK47349.1 BAK47427.1 BAK47427.1 BAK47428.1 BAK47428.1 BAK47429.1 BAK47429.1 AmiC-2 AmiC-2 GntR-3 GntR-3 BAK47628.1 BAK47628.1 MurI MurI BAK47630.1 BAK47630.1 BAK47638.1 BAK47638.1 BAK47639.1 BAK47639.1 BAK47928.1 BAK47928.1 BAK48076.1 BAK48076.1 Maf Maf WecD-2 WecD-2 BAK48110.1 BAK48110.1 BAK48141.1 BAK48141.1 BAK48142.1 BAK48142.1 BAK48143.1 BAK48143.1 LytS-4 LytS-4 rnj rnj BAK48146.1 BAK48146.1 BAK48147.1 BAK48147.1 BAK48148.1 BAK48148.1 Era Era Rnd Rnd BAK48177.1 BAK48177.1 BAK48178.1 BAK48178.1 BAK48185.1 BAK48185.1 rlmH rlmH BAK48197.1 BAK48197.1 ybeY ybeY BAK48199.1 BAK48199.1 BAK48200.1 BAK48200.1 BAK48201.1 BAK48201.1 miaA miaA MetC MetC RadC-2 RadC-2 MreB MreB BAK48208.1 BAK48208.1 AraB AraB BAK48210.1 BAK48210.1 FtsW-2 FtsW-2 MgsA MgsA BAK48213.1 BAK48213.1 BAK48214.1 BAK48214.1 BAK48215.1 BAK48215.1 BAK48216.1 BAK48216.1 sepF sepF LspA LspA BAK48219.1 BAK48219.1 BAK48220.1 BAK48220.1 BAK48221.1 BAK48221.1 Dtd Dtd BAK48227.1 BAK48227.1 BAK48267.1 BAK48267.1 BAK48268.1 BAK48268.1 UbiD UbiD MutT-3 MutT-3 BAK48271.1 BAK48271.1 BAK48272.1 BAK48272.1 BAK48273.1 BAK48273.1 BAK48274.1 BAK48274.1 RuvB RuvB ruvA ruvA BAK48277.1 BAK48277.1 BAK48278.1 BAK48278.1 miaB miaB larC larC BAK48281.1 BAK48281.1 BAK48282.1 BAK48282.1 proB proB BAK48284.1 BAK48284.1 BAK48383.1 BAK48383.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AmiCN-acetylmuramoyl-L-alanine amidase. (340 aa)
BAK46010.1Hypothetical protein. (829 aa)
murEHypothetical protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (486 aa)
BAK46187.1Hypothetical protein. (338 aa)
BAK46191.1Hypothetical protein. (332 aa)
ftsZHypothetical protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (377 aa)
BAK46220.1Hypothetical protein. (309 aa)
FtsWBacterial cell division membrane protein; Belongs to the SEDS family. (385 aa)
murDHypothetical protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (452 aa)
RfeUDP-N-acetylmuramyl pentapeptide phosphotransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (317 aa)
BAK46224.1Hypothetical protein. (612 aa)
FtsXCell division protein. (164 aa)
rsmHHypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (314 aa)
mraZUncharacterized BCR; Belongs to the MraZ family. (143 aa)
BAK46231.1Hypothetical protein. (168 aa)
ProAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (426 aa)
BAK46289.1Hypothetical protein. (425 aa)
BAK46338.1Hypothetical protein. (160 aa)
BAK46481.1Hypothetical protein. (690 aa)
BAK46493.1Hypothetical protein. (89 aa)
BAK46494.1Hypothetical protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (270 aa)
BAK46497.1Predicted metal-dependent membrane protease. (316 aa)
ProCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
BAK46721.1Hypothetical protein. (116 aa)
murGHypothetical protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (359 aa)
BAK46732.1Hypothetical protein. (218 aa)
BAK46733.1Hypothetical protein. (468 aa)
NUC1DNA/RNA endonuclease G, NUC1. (286 aa)
PolCDNA polymerase III alpha subunit; The Gram-positive type. (533 aa)
BAK46738.1Hypothetical protein. (59 aa)
BAK46739.1Predicted membrane protein. (410 aa)
BAK46740.1Hypothetical protein. (268 aa)
irB11Type IV secretory pathway; VirB11 component and related ATPase involved in archaeal flagella biosynthesis. (121 aa)
BAK46790.1Hypothetical protein. (309 aa)
GcvPGlycine cleavage system protein P; Pyridoxal-binding, C-terminal domain. (838 aa)
SpoVKATPase of the AAA+ class. (1050 aa)
BAK46824.1Hypothetical protein. (162 aa)
BAK46825.1Hypothetical protein; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (171 aa)
SUA5Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (352 aa)
BAK46827.1Hypothetical protein. (574 aa)
BAK46828.1Hypothetical protein. (72 aa)
BAK46829.1Hypothetical protein. (256 aa)
BAK46831.1Hypothetical protein. (73 aa)
BAK46852.1Hypothetical protein. (191 aa)
BAK46854.1Hypothetical protein. (832 aa)
minCHypothetical protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (239 aa)
BAK46860.1Hypothetical protein. (420 aa)
murFHypothetical protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (560 aa)
DdlA-2D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (348 aa)
BAK46888.1Hypothetical protein. (371 aa)
BAK46889.1Hypothetical protein. (399 aa)
BAK46911.1Hypothetical protein. (321 aa)
BAK46937.1Hypothetical protein. (315 aa)
SojATPase involved in chromosome partitioning. (255 aa)
BAK46939.1Hypothetical protein; Belongs to the ParB family. (440 aa)
BAK46940.1Hypothetical protein. (172 aa)
BAK46941.1Hypothetical protein. (295 aa)
HipB-3Predicted transcriptional regulator. (283 aa)
BAK47075.1Hypothetical protein. (271 aa)
BAK47076.1Hypothetical protein. (60 aa)
BAK47077.1Predicted endonuclease distantly related to archaeal Holliday junction resolvase. (232 aa)
BAK47100.1Hypothetical protein; Belongs to the peptidase S11 family. (535 aa)
BAK47125.1Hypothetical protein. (163 aa)
BAK47129.1Hypothetical protein; Belongs to the DnaA family. (328 aa)
BAK47130.1Hypothetical protein. (355 aa)
murCHypothetical protein; Cell wall formation; Belongs to the MurCDEF family. (459 aa)
murAHypothetical protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (430 aa)
PcnBtRNA nucleotidyltransferase; poly(A) polymerase. (447 aa)
BAK47149.1Septum formation initiator. (132 aa)
BAK47275.1Hypothetical protein. (205 aa)
BAK47279.1Hypothetical protein. (88 aa)
murBHypothetical protein; Cell wall formation. (300 aa)
BAK47295.1Hypothetical protein. (827 aa)
WecGTeichoic acid biosynthesis protein. (239 aa)
BAK47297.1Hypothetical protein. (360 aa)
ftsEHypothetical protein; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
FtsX-2Cell division protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (302 aa)
BAK47349.1Hypothetical protein. (462 aa)
BAK47427.1Hypothetical protein. (251 aa)
BAK47428.1Uncharacterized BCR. (107 aa)
BAK47429.1Hypothetical protein. (280 aa)
AmiC-2N-acetylmuramoyl-L-alanine amidase. (388 aa)
GntR-3Transcriptional regulator. (224 aa)
BAK47628.1Hypothetical protein. (144 aa)
MurIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (276 aa)
BAK47630.1Hypothetical protein. (147 aa)
BAK47638.1Uncharacterized Fe-S protein. (47 aa)
BAK47639.1Hypothetical protein. (460 aa)
BAK47928.1Hypothetical protein. (275 aa)
BAK48076.1Hypothetical protein. (171 aa)
MafNucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (201 aa)
WecD-2Histone acetyltransferase HPA2; Related acetyltransferase. (85 aa)
BAK48110.1Hypothetical protein. (284 aa)
BAK48141.1Hypothetical protein. (437 aa)
BAK48142.1Hypothetical protein; Belongs to the UPF0297 family. (87 aa)
BAK48143.1Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (153 aa)
LytS-4Predicted signal transduction protein with a C-terminal ATPase domain. (87 aa)
rnjHypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (561 aa)
BAK48146.1Hypothetical protein. (220 aa)
BAK48147.1Hypothetical protein. (413 aa)
BAK48148.13-carboxymuconate cyclase. (350 aa)
EraGTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (304 aa)
RndRibonuclease D. (1054 aa)
BAK48177.1Hypothetical protein. (419 aa)
BAK48178.1Hypothetical protein. (253 aa)
BAK48185.1Hypothetical protein. (104 aa)
rlmHUncharacterized ACR protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (159 aa)
BAK48197.1Hypothetical protein. (334 aa)
ybeYHypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (165 aa)
BAK48199.1Hypothetical protein. (555 aa)
BAK48200.1Hypothetical protein. (418 aa)
BAK48201.1Uncharacterized FAD-dependent dehydrogenase. (532 aa)
miaAHypothetical protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (327 aa)
MetCCystathionine gamma-synthase. (434 aa)
RadC-2DNA repair protein; Belongs to the UPF0758 family. (231 aa)
MreBHSP70 class molecular chaperones involved in cell morphogenesis. (338 aa)
BAK48208.1Hypothetical protein; Involved in formation and maintenance of cell shape. (272 aa)
AraBRibulose kinase. (173 aa)
BAK48210.1Hypothetical protein. (946 aa)
FtsW-2Bacterial cell division membrane protein; Belongs to the SEDS family. (376 aa)
MgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (131 aa)
BAK48213.1Hypothetical protein; Belongs to the peptidase S11 family. (334 aa)
BAK48214.1Predicted ATPase involved in pili biogenesis, PilT homolog. (139 aa)
BAK48215.1Hypothetical protein. (468 aa)
BAK48216.1Predicted enzyme with a TIM-barrel fold; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (230 aa)
sepFUncharacterized BCR; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (181 aa)
LspALipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (180 aa)
BAK48219.1Hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (309 aa)
BAK48220.1Predicted Na+-dependent transporter. (320 aa)
BAK48221.1Hypothetical protein; Belongs to the 'phage' integrase family. (356 aa)
DtdD-Tyr-tRNAtyr deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (148 aa)
BAK48227.1Methenyl tetrahydrofolate cyclohydrolase. (212 aa)
BAK48267.1Hypothetical protein. (149 aa)
BAK48268.1Hypothetical protein. (305 aa)
UbiDRelated decarboxylase. (115 aa)
MutT-3NTP pyrophosphohydrolase including oxidative damage repair enzyme; Belongs to the Nudix hydrolase family. (146 aa)
BAK48271.1Hypothetical protein. (503 aa)
BAK48272.1Hypothetical protein; Belongs to the SEDS family. (497 aa)
BAK48273.1Hypothetical protein. (724 aa)
BAK48274.1Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (111 aa)
RuvBHolliday junction resolvasome helicase subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
ruvAHypothetical protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa)
BAK48277.1Hypothetical protein. (168 aa)
BAK48278.1Hypothetical protein. (133 aa)
miaBHypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (490 aa)
larCHypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (458 aa)
BAK48281.1Hypothetical protein. (236 aa)
BAK48282.15-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (189 aa)
proBHypothetical protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (295 aa)
BAK48284.1Hypothetical protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. (318 aa)
BAK48383.1Hypothetical protein. (302 aa)
Your Current Organism:
Clostridium sp. SY8519
NCBI taxonomy Id: 1042156
Other names: C. sp. SY8519
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