Your Input: | |||||
ispH | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (640 aa) | ||||
cmk | Hypothetical protein. (234 aa) | ||||
RibF-2 | FAD synthase; Belongs to the ribF family. (306 aa) | ||||
ispG | Hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (348 aa) | ||||
dxr | Hypothetical protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (380 aa) | ||||
BAK48317.1 | Hypothetical protein; Belongs to the CDS family. (287 aa) | ||||
PyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (231 aa) | ||||
WbbJ-2 | Acetyltransferase; The isoleucine patch superfamily. (228 aa) | ||||
nadK | Ribosomal protein S3; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (290 aa) | ||||
dxs | Hypothetical protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (621 aa) | ||||
IspA | Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (295 aa) | ||||
folE | Hypothetical protein. (194 aa) | ||||
RpsA | Ribosomal protein S1. (231 aa) | ||||
deoB | Hypothetical protein; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (383 aa) | ||||
BAK48438.1 | Hypothetical protein. (378 aa) | ||||
Cmk-5 | Cytidylate kinase 2. (202 aa) | ||||
BAK48459.1 | Hypothetical protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (477 aa) | ||||
Cmk-3 | Cytidylate kinase 2. (201 aa) | ||||
purC | Hypothetical protein; Belongs to the SAICAR synthetase family. (293 aa) | ||||
HI80 | Thiamine pyrophosphokinase. (221 aa) | ||||
pyrB | Hypothetical protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (309 aa) | ||||
BAK48569.1 | Hypothetical protein. (141 aa) | ||||
ThyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (282 aa) | ||||
IspE | 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (290 aa) | ||||
carA | Hypothetical protein; Belongs to the CarA family. (356 aa) | ||||
CarB | Carbamoylphosphate synthase large subunit; Split gene in MJ; Belongs to the CarB family. (1067 aa) | ||||
ThiF | Dinucleotide-utilizing enzyme involved in molybdopterin; Thiamine biosynthesis family 2. (267 aa) | ||||
ThiS | Sulfur transfer protein involved in thiamine biosynthesis. (68 aa) | ||||
thiC | Hypothetical protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (436 aa) | ||||
BAK47427.1 | Hypothetical protein. (251 aa) | ||||
PurB | Adenylosuccinate lyase. (440 aa) | ||||
PyrC-3 | Dihydroorotase; Related cyclic amidohydrolase. (457 aa) | ||||
PyrD-2 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (315 aa) | ||||
BAK47402.1 | Hypothetical protein. (252 aa) | ||||
upp | Hypothetical protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa) | ||||
GldA | Glycerol dehydrogenase; Related enzyme. (427 aa) | ||||
mobA | Hypothetical protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (395 aa) | ||||
SpoT-2 | Guanosine polyphosphate pyrophosphohydrolase/synthetases. (142 aa) | ||||
BmrU | Predicted kinase related to diacylglycerol kinase. (307 aa) | ||||
BAK47207.1 | Hypothetical protein; Belongs to the NadC/ModD family. (286 aa) | ||||
BAK47205.1 | Hypothetical protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (272 aa) | ||||
BAK47151.1 | Hypothetical protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (174 aa) | ||||
BAK47128.1 | Hypothetical protein; Belongs to the ribose-phosphate pyrophosphokinase family. (394 aa) | ||||
atpC | Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa) | ||||
AtpD | F0F1-type ATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (462 aa) | ||||
atpG | Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (296 aa) | ||||
AtpA | F0F1-type ATP synthase alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (502 aa) | ||||
AtpH | F0F1-type ATP synthase delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (151 aa) | ||||
atpF | Hypothetical protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (167 aa) | ||||
atpE-2 | Hypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (72 aa) | ||||
atpB-2 | Hypothetical protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (256 aa) | ||||
Pta | Phosphotransacetylase. (327 aa) | ||||
CyaA | Adenylate cyclase, family 3; Some proteins contain HAMP domain. (444 aa) | ||||
BAK46861.1 | Hypothetical protein; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (243 aa) | ||||
BAK46840.1 | Hypothetical protein. (202 aa) | ||||
SpoT | Guanosine polyphosphate pyrophosphohydrolase/synthetases; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (779 aa) | ||||
coaX | Hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa) | ||||
BAK46644.1 | Hypothetical protein. (343 aa) | ||||
BAK46586.1 | Hypothetical protein. (197 aa) | ||||
moaC | Hypothetical protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (160 aa) | ||||
MoeA | Molybdopterin biosynthesis enzyme; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (342 aa) | ||||
BAK46545.1 | Hypothetical protein. (163 aa) | ||||
BAK46544.1 | Hypothetical protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (345 aa) | ||||
BAK46543.1 | Hypothetical protein. (144 aa) | ||||
guaB | Hypothetical protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) | ||||
BAK46503.1 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (485 aa) | ||||
BAK46492.1 | Hypothetical protein. (220 aa) | ||||
PyrC-2 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (427 aa) | ||||
pyrF | Hypothetical protein; Belongs to the OMP decarboxylase family. Type 2 subfamily. (307 aa) | ||||
pyrK | Hypothetical protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (261 aa) | ||||
PyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (301 aa) | ||||
pyrE | Hypothetical protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (224 aa) | ||||
PurE | Phosphoribosylcarboxyaminoimidazole mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (167 aa) | ||||
PurM | AIR synthetase. (341 aa) | ||||
purN | Hypothetical protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (209 aa) | ||||
PurD | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (424 aa) | ||||
BAK46473.1 | Uncharacterized BCR. (203 aa) | ||||
guaA | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. (525 aa) | ||||
thiE | Hypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (220 aa) | ||||
thiM | Hypothetical protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (273 aa) | ||||
BAK46424.1 | Hypothetical protein. (141 aa) | ||||
Cmk-2 | Cytidylate kinase 2. (199 aa) | ||||
Cmk | Cytidylate kinase 2. (196 aa) | ||||
purF | Hypothetical protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (468 aa) | ||||
pyrG | Hypothetical protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (539 aa) | ||||
BAK46328.1 | Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (461 aa) | ||||
accD | Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (260 aa) | ||||
accA | Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (276 aa) | ||||
fabZ | Hypothetical protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (144 aa) | ||||
BAK46295.1 | Hypothetical protein. (220 aa) | ||||
BAK46281.1 | Hypothetical protein. (258 aa) | ||||
purA | Hypothetical protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (426 aa) | ||||
BAK46200.1 | Hypothetical protein. (1267 aa) | ||||
dacA | Uncharacterized ACR protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (296 aa) | ||||
BAK46179.1 | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. (240 aa) | ||||
BAK46092.1 | Hypothetical protein. (269 aa) | ||||
BAK46051.1 | Hypothetical protein. (334 aa) | ||||
BAK46015.1 | Hypothetical protein. (268 aa) | ||||
Udp | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (259 aa) | ||||
PurF | Glutamine phosphoribosylpyrophosphate amidotransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (472 aa) | ||||
atpE | Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (197 aa) | ||||
BAK45980.1 | Hypothetical protein. (106 aa) | ||||
NtpA | Archaeal/vacuolar-type H+-ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (589 aa) | ||||
atpB | Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (457 aa) | ||||
atpD | Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (234 aa) | ||||
thiG | Hypothetical protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (257 aa) | ||||
ThiE | Thiamine monophosphate synthase. (201 aa) | ||||
Cmk-4 | Cytidylate kinase 2. (198 aa) | ||||
adk | Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) | ||||
BAK47824.1 | Hypothetical protein. (206 aa) | ||||
Idi | Isopentenyl-diphosphate isomerase. (176 aa) | ||||
BAK47912.1 | Hypothetical protein. (266 aa) | ||||
Cls | Phosphatidylserine; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (517 aa) | ||||
IspF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (180 aa) | ||||
coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (207 aa) | ||||
BAK48026.1 | Hypothetical protein. (237 aa) | ||||
BAK48027.1 | Hypothetical protein. (391 aa) | ||||
ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa) | ||||
plsX | Hypothetical protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (343 aa) | ||||
plsY | Predicted membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (218 aa) | ||||
gpsA | Hypothetical protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (342 aa) | ||||
BAK48072.1 | Hypothetical protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (145 aa) | ||||
nadE | Hypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (646 aa) | ||||
BAK48101.1 | Metal-dependent hydrolase of the beta-lactamase superfamily II. (280 aa) | ||||
FdhD | Uncharacterized protein required for formate dehydrogenase activity; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (286 aa) | ||||
thiI | Hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (399 aa) | ||||
Dfp | Phosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa) | ||||
folD | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) | ||||
xpt | Hypothetical protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa) | ||||
BAK48229.1 | Metal-dependent hydrolase of the beta-lactamase superfamily II. (259 aa) | ||||
rsfS | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (311 aa) | ||||
nadD | Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (209 aa) | ||||
coaD | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa) | ||||
BAK48255.1 | Hypothetical protein; Belongs to the CinA family. (156 aa) | ||||
BAK48256.1 | Hypothetical protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (180 aa) | ||||
Gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (212 aa) | ||||
BAK48281.1 | Hypothetical protein. (236 aa) |