11 items (Thermococcus sp. 4557) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hypA	Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (139 aa)
	GQS_04220	Chromosome partitioning ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (243 aa)
	GQS_04225	COG0680 Ni,Fe-hydrogenase maturation factor. (157 aa)
	GQS_04230	Hypothetical protein. (77 aa)
	GQS_04235	Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor. (74 aa)
	GQS_04240	Hydrogenase isoenzymes formation protein HypD; COG0409 Hydrogenase maturation factor. (372 aa)
	GQS_04245	COG0068 Hydrogenase maturation factor. (772 aa)
	GQS_04250	COG1708 Predicted nucleotidyltransferases. (108 aa)
	GQS_04255	Hypothetical protein; COG1895 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN. (130 aa)
	GQS_04260	Hydrogenase expression/formation protein HypE; COG0309 Hydrogenase maturation factor. (338 aa)
	GQS_04265	Hypothetical protein. (97 aa)

Your Current Organism:

Thermococcus sp. 4557

NCBI taxonomy Id: 1042877
Other names: T. sp. 4557

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GQS_04220	GQS_04225	GQS_04220	GQS_04225	Chromosome partitioning ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	COG0680 Ni,Fe-hydrogenase maturation factor.	0.751
GQS_04220	GQS_04230	GQS_04220	GQS_04230	Chromosome partitioning ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	Hypothetical protein.	0.622
GQS_04220	GQS_04235	GQS_04220	GQS_04235	Chromosome partitioning ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor.	0.423
GQS_04220	GQS_04240	GQS_04220	GQS_04240	Chromosome partitioning ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	Hydrogenase isoenzymes formation protein HypD; COG0409 Hydrogenase maturation factor.	0.421
GQS_04220	hypA	GQS_04220	GQS_04215	Chromosome partitioning ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.917
GQS_04225	GQS_04220	GQS_04225	GQS_04220	COG0680 Ni,Fe-hydrogenase maturation factor.	Chromosome partitioning ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	0.751
GQS_04225	GQS_04230	GQS_04225	GQS_04230	COG0680 Ni,Fe-hydrogenase maturation factor.	Hypothetical protein.	0.782
GQS_04225	GQS_04235	GQS_04225	GQS_04235	COG0680 Ni,Fe-hydrogenase maturation factor.	Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor.	0.665
GQS_04225	GQS_04240	GQS_04225	GQS_04240	COG0680 Ni,Fe-hydrogenase maturation factor.	Hydrogenase isoenzymes formation protein HypD; COG0409 Hydrogenase maturation factor.	0.646
GQS_04225	GQS_04245	GQS_04225	GQS_04245	COG0680 Ni,Fe-hydrogenase maturation factor.	COG0068 Hydrogenase maturation factor.	0.619
GQS_04225	GQS_04260	GQS_04225	GQS_04260	COG0680 Ni,Fe-hydrogenase maturation factor.	Hydrogenase expression/formation protein HypE; COG0309 Hydrogenase maturation factor.	0.462
GQS_04225	hypA	GQS_04225	GQS_04215	COG0680 Ni,Fe-hydrogenase maturation factor.	Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.871
GQS_04230	GQS_04220	GQS_04230	GQS_04220	Hypothetical protein.	Chromosome partitioning ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	0.622
GQS_04230	GQS_04225	GQS_04230	GQS_04225	Hypothetical protein.	COG0680 Ni,Fe-hydrogenase maturation factor.	0.782
GQS_04230	GQS_04235	GQS_04230	GQS_04235	Hypothetical protein.	Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor.	0.481
GQS_04230	GQS_04240	GQS_04230	GQS_04240	Hypothetical protein.	Hydrogenase isoenzymes formation protein HypD; COG0409 Hydrogenase maturation factor.	0.481
GQS_04230	hypA	GQS_04230	GQS_04215	Hypothetical protein.	Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.622
GQS_04235	GQS_04220	GQS_04235	GQS_04220	Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor.	Chromosome partitioning ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	0.423
GQS_04235	GQS_04225	GQS_04235	GQS_04225	Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor.	COG0680 Ni,Fe-hydrogenase maturation factor.	0.665
GQS_04235	GQS_04230	GQS_04235	GQS_04230	Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor.	Hypothetical protein.	0.481