10 items (Thermococcus sp. 4557) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GQS_02345	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit. (276 aa)
	GQS_02350	COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit. (230 aa)
	GQS_02355	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit. (392 aa)
	GQS_02430	Formate hydrogenlyase II subunit F; COG3262 Ni,Fe-hydrogenase III component G. (544 aa)
	GQS_02475	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit. (429 aa)
	hypA	Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (139 aa)
	GQS_04445	Nickel responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (138 aa)
	GQS_04990	H-II alpha (hydrogenase subunit alpha); COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit. (415 aa)
	GQS_07460	Membrane-bound hydrogenase MBH 2, subunit Mbh2L (NiFe hydrogenase catalytic subunit); COG3261 Ni,Fe-hydrogenase III large subunit. (412 aa)
	GQS_07530	COG3261 Ni,Fe-hydrogenase III large subunit. (431 aa)

Your Current Organism:

Thermococcus sp. 4557

NCBI taxonomy Id: 1042877
Other names: T. sp. 4557

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GQS_02345	GQS_02350	GQS_02345	GQS_02350	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.	COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit.	0.999
GQS_02345	GQS_02355	GQS_02345	GQS_02355	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	0.999
GQS_02345	GQS_02430	GQS_02345	GQS_02430	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.	Formate hydrogenlyase II subunit F; COG3262 Ni,Fe-hydrogenase III component G.	0.408
GQS_02345	GQS_02475	GQS_02345	GQS_02475	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	0.667
GQS_02345	GQS_04990	GQS_02345	GQS_04990	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.	H-II alpha (hydrogenase subunit alpha); COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	0.667
GQS_02350	GQS_02345	GQS_02350	GQS_02345	COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit.	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.	0.999
GQS_02350	GQS_02355	GQS_02350	GQS_02355	COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit.	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	0.999
GQS_02350	GQS_02475	GQS_02350	GQS_02475	COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit.	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	0.779
GQS_02350	GQS_04990	GQS_02350	GQS_04990	COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit.	H-II alpha (hydrogenase subunit alpha); COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	0.787
GQS_02355	GQS_02345	GQS_02355	GQS_02345	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.	0.999
GQS_02355	GQS_02350	GQS_02355	GQS_02350	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit.	0.999
GQS_02355	GQS_02430	GQS_02355	GQS_02430	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	Formate hydrogenlyase II subunit F; COG3262 Ni,Fe-hydrogenase III component G.	0.451
GQS_02355	hypA	GQS_02355	GQS_04215	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.815
GQS_02430	GQS_02345	GQS_02430	GQS_02345	Formate hydrogenlyase II subunit F; COG3262 Ni,Fe-hydrogenase III component G.	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.	0.408
GQS_02430	GQS_02355	GQS_02430	GQS_02355	Formate hydrogenlyase II subunit F; COG3262 Ni,Fe-hydrogenase III component G.	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	0.451
GQS_02430	GQS_07460	GQS_02430	GQS_07460	Formate hydrogenlyase II subunit F; COG3262 Ni,Fe-hydrogenase III component G.	Membrane-bound hydrogenase MBH 2, subunit Mbh2L (NiFe hydrogenase catalytic subunit); COG3261 Ni,Fe-hydrogenase III large subunit.	0.426
GQS_02430	GQS_07530	GQS_02430	GQS_07530	Formate hydrogenlyase II subunit F; COG3262 Ni,Fe-hydrogenase III component G.	COG3261 Ni,Fe-hydrogenase III large subunit.	0.431
GQS_02430	hypA	GQS_02430	GQS_04215	Formate hydrogenlyase II subunit F; COG3262 Ni,Fe-hydrogenase III component G.	Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.649
GQS_02475	GQS_02345	GQS_02475	GQS_02345	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.	0.667
GQS_02475	GQS_02350	GQS_02475	GQS_02350	COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit.	COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit.	0.779