STRINGSTRING
GQS_08485 GQS_08485 GQS_07745 GQS_07745 GQS_07740 GQS_07740 GQS_07620 GQS_07620 GQS_04240 GQS_04240 polC polC radA radA GQS_07035 GQS_07035 GQS_06960 GQS_06960 GQS_06330 GQS_06330 GQS_06105 GQS_06105 GQS_05270 GQS_05270 GQS_05605 GQS_05605 topA topA rgy rgy GQS_03105 GQS_03105 GQS_02930 GQS_02930 GQS_02665 GQS_02665 GQS_02490 GQS_02490 GQS_02040 GQS_02040 GQS_01710 GQS_01710 dys dys rtcB rtcB GQS_01240 GQS_01240 GQS_00730 GQS_00730 hypA hypA GQS_04225 GQS_04225 GQS_04235 GQS_04235 GQS_05040 GQS_05040 GQS_04260 GQS_04260 GQS_04245 GQS_04245 GQS_09835 GQS_09835 hel308 hel308 GQS_08505 GQS_08505
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GQS_08485COG0456 Acetyltransferases. (167 aa)
GQS_07745COG0095 Lipoate-protein ligase A. (249 aa)
GQS_07740COG0681 Signal peptidase I. (158 aa)
GQS_07620COG0681 Signal peptidase I. (189 aa)
GQS_04240Hydrogenase isoenzymes formation protein HypD; COG0409 Hydrogenase maturation factor. (372 aa)
polCDNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1461 aa)
radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (354 aa)
GQS_07035GCN5-like N-acetyltransferase; COG0456 Acetyltransferases. (205 aa)
GQS_06960Type II/IV secretion system ATPase; COG4962 Flp pilus assembly protein, ATPase CpaF. (622 aa)
GQS_06330COG0095 Lipoate-protein ligase A. (267 aa)
GQS_06105Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (910 aa)
GQS_05270COG0417 DNA polymerase elongation subunit (family B). (775 aa)
GQS_05605COG0681 Signal peptidase I. (354 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (719 aa)
rgyReverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1226 aa)
GQS_03105Phosphohydrolase. (424 aa)
GQS_02930Hypothetical protein; COG1266 Predicted metal-dependent membrane protease. (261 aa)
GQS_02665COG0095 Lipoate-protein ligase A. (92 aa)
GQS_02490Hydrogenase-specific maturation endopeptidase; COG0680 Ni,Fe-hydrogenase maturation factor. (149 aa)
GQS_02040Membrane-associated metalloprotease; COG1266 Predicted metal-dependent membrane protease. (200 aa)
GQS_01710HypE; COG0309 Hydrogenase maturation factor. (332 aa)
dysPutative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (336 aa)
rtcBHypothetical protein; Belongs to the RtcB family. (960 aa)
GQS_01240HypE; COG0309 Hydrogenase maturation factor. (330 aa)
GQS_00730COG0456 Acetyltransferases. (216 aa)
hypAHydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (139 aa)
GQS_04225COG0680 Ni,Fe-hydrogenase maturation factor. (157 aa)
GQS_04235Hydrogenase expression/formation protein HypC; COG0298 Hydrogenase maturation factor. (74 aa)
GQS_05040MCM2/3/5 family DNA replication licensing factor; COG1241 Predicted ATPase involved in replication control, Cdc46/Mcm family. (1316 aa)
GQS_04260Hydrogenase expression/formation protein HypE; COG0309 Hydrogenase maturation factor. (338 aa)
GQS_04245COG0068 Hydrogenase maturation factor. (772 aa)
GQS_09835Hypothetical protein; COG4606 ABC-type enterochelin transport system, permease component. (222 aa)
hel308Ski2-like helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (726 aa)
GQS_08505Replication factor C small subunit; COG0470 ATPase involved in DNA replication. (866 aa)
Your Current Organism:
Thermococcus sp. 4557
NCBI taxonomy Id: 1042877
Other names: T. sp. 4557
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