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| | GQS_00060 | COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (320 aa) |
| | rps28e | COG2053 Ribosomal protein S28E/S33; Belongs to the eukaryotic ribosomal protein eS28 family. (70 aa) |
| | rpl24e | 50S ribosomal protein L24e; Binds to the 23S rRNA. (68 aa) |
| | rad50 | Chromosome segregation protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (887 aa) |
| | mre11 | DNA double-strand break repair protein mre11 (mre11); Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (470 aa) |
| | GQS_00335 | COG1454 Alcohol dehydrogenase, class IV. (378 aa) |
| | GQS_00355 | Hypothetical protein; COG0517 FOG: CBS domain. (177 aa) |
| | albA | DNA/RNA-binding protein albA; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (91 aa) |
| | GQS_00380 | COG1342 Predicted DNA-binding proteins; Belongs to the UPF0251 family. (118 aa) |
| | GQS_00420 | Iron-molybdenum cofactor-binding protein. (166 aa) |
| | GQS_00430 | Iron-molybdenum cofactor-binding protein. (204 aa) |
| | GQS_00460 | IS element ISTsi1 orfB, putative trasposase; COG0675 Transposase and inactivated derivatives. (393 aa) |
| | GQS_00470 | COG2020 Putative protein-S-isoprenylcysteine methyltransferase. (86 aa) |
| | GQS_00550 | COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain. (213 aa) |
| | GQS_00610 | Hypothetical protein. (174 aa) |
| | GQS_00640 | GNAT family N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (175 aa) |
| | GQS_00645 | Rubrerythrin-related protein. (159 aa) |
| | GQS_00650 | Linocin_M18 bacteriocin protein. (100 aa) |
| | GQS_00670 | Rubrerythrin-related protein. (174 aa) |
| | GQS_00715 | Hypothetical protein; COG0471 Di- and tricarboxylate transporters. (345 aa) |
| | GQS_00810 | ATPase; COG1672 Predicted ATPase (AAA+ superfamily). (466 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (429 aa) |
| | cobB | COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. (250 aa) |
| | GQS_00850 | Hydrolase; COG1011 Predicted hydrolase (HAD superfamily). (242 aa) |
| | GQS_00970 | Peroxiredoxin, bacterioferritin comigratory protein; COG1225 Peroxiredoxin. (154 aa) |
| | GQS_01010 | Oligosaccharyl transferase, STT3 subunit; COG1287 Uncharacterized membrane protein, required for N-linked glycosylation. (957 aa) |
| | top6A | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (386 aa) |
| | GQS_01115 | COG1078 HD superfamily phosphohydrolases. (358 aa) |
| | GQS_01125 | Hypothetical protein; COG1672 Predicted ATPase (AAA+ superfamily). (470 aa) |
| | rps10p | 30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | taw2 | Hypothetical protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (279 aa) |
| | GQS_01255 | DEAD/DEAH box helicase domain-containing protein; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster. (899 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (285 aa) |
| | rtcB | Hypothetical protein; Belongs to the RtcB family. (960 aa) |
| | GQS_01370 | Glucose-1-dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (281 aa) |
| | GQS_01420 | COG1672 Predicted ATPase (AAA+ superfamily). (453 aa) |
| | GQS_01445 | COG1078 HD superfamily phosphohydrolases. (416 aa) |
| | GQS_01555 | moxR-type AAA ATPase, putative chaperone protein (moxR); COG0714 MoxR-like ATPases. (324 aa) |
| | GQS_01595 | Met-10 like-protein, putative SAM-dependent methyltransferase; COG2520 Predicted methyltransferase. (332 aa) |
| | GQS_01615 | Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain. (114 aa) |
| | GQS_01645 | COG1437 Adenylate cyclase, class 2 (thermophilic). (170 aa) |
| | ubiX | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (177 aa) |
| | GQS_01700 | COG4818 Predicted membrane protein. (120 aa) |
| | GQS_01735 | COG1011 Predicted hydrolase (HAD superfamily). (222 aa) |
| | rpl35ae | COG2451 Ribosomal protein L35AE/L33A; Belongs to the eukaryotic ribosomal protein eL33 family. (88 aa) |
| | GQS_01750 | COG1814 Uncharacterized membrane protein. (364 aa) |
| | GQS_01820 | Cobalamin adenosyltransferase. (171 aa) |
| | GQS_01865 | Permease, Auxin efflux carrier protein-like protein; COG0679 Predicted permeases. (293 aa) |
| | GQS_01905 | Chromosome partitioning protein ParB-like protein; COG1475 Predicted transcriptional regulators. (242 aa) |
| | GQS_01955 | COG1215 Glycosyltransferases, probably involved in cell wall biogenesis. (360 aa) |
| | ftsY | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (327 aa) |
| | GQS_02180 | COG1672 Predicted ATPase (AAA+ superfamily). (460 aa) |
| | GQS_02275 | Putative kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (182 aa) |
| | GQS_02310 | Hypothetical protein. (69 aa) |
| | GQS_02315 | Phosphoesterase; COG1226 Kef-type K+ transport systems, predicted NAD-binding component. (487 aa) |
| | GQS_02360 | COG1454 Alcohol dehydrogenase, class IV. (405 aa) |
| | GQS_02465 | Cytochrome-c3 hydrogenase subunit gamma; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. (294 aa) |
| | GQS_02495 | Fe-S cluster containing protein, SufBD related (SufBD); COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component. (444 aa) |
| | GQS_02540 | Membrane protein, conserved; COG1836 Predicted membrane protein. (239 aa) |
| | rps3ae | COG1890 Ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (200 aa) |
| | rps15p | COG0184 Ribosomal protein S15P/S13E. (151 aa) |
| | GQS_02645 | Prokaryotic ATPase, AAA superfamily protein; COG1672 Predicted ATPase (AAA+ superfamily). (357 aa) |
| | hcp | Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (455 aa) |
| | GQS_02830 | Transmembrane electron transport protein; COG0785 Cytochrome c biogenesis protein. (242 aa) |
| | GQS_02835 | Glutaredoxin-related protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (193 aa) |
| | rpl37ae | 50S ribosomal protein L37Ae; Binds to the 23S rRNA. (86 aa) |
| | GQS_02920 | Ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome. (210 aa) |
| | GQS_02955 | Phosphoesterase, recJ-like, containing a DHHA1 domain; COG0618 Exopolyphosphatase-related proteins. (327 aa) |
| | GQS_03005 | Bis(5'-adenosyl)-triphosphatase; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (166 aa) |
| | nep1 | Ribosome biogenesis protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (219 aa) |
| | GQS_03090 | NapA-type sodium/hydrogen antiporter; COG0475 Kef-type K+ transport systems, membrane components. (439 aa) |
| | ksgA | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (273 aa) |
| | rpl21e | COG2139 Ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (98 aa) |
| | GQS_03225 | COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (408 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (267 aa) |
| | GQS_03260 | DNA/RNA repair helicase; COG1061 DNA or RNA helicases of superfamily II. (466 aa) |
| | GQS_03400 | COG1437 Adenylate cyclase, class 2 (thermophilic). (177 aa) |
| | GQS_03450 | COG1084 Predicted GTPase. (359 aa) |
| | rps8e | COG2007 Ribosomal protein S8E. (130 aa) |
| | GQS_03490 | Bifunctional carboxypeptidase/aminoacylase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (383 aa) |
| | GQS_03545 | Hydrolase; COG1011 Predicted hydrolase (HAD superfamily). (214 aa) |
| | GQS_03590 | COG1378 Predicted transcriptional regulators. (263 aa) |
| | GQS_03690 | Geranylgeranyl hydrogenase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (396 aa) |
| | rpl11p | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (163 aa) |
| | rpl1P | 50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (216 aa) |
| | rplP0 | Acidic ribosomal protein P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (339 aa) |
| | rpl12p | 50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (105 aa) |
| | GQS_03775 | COG2036 Histones H3 and H4. (67 aa) |
| | GQS_03785 | COG1658 Small primase-like proteins (Toprim domain); Belongs to the UPF0292 family. (133 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (469 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (625 aa) |
| | GQS_03925 | Hydrolase, HAD superfamily; COG0546 Predicted phosphatases. (226 aa) |
| | rpl30e | COG1911 Ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (102 aa) |
| | rps12P | 30S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa) |
| | rps7 | 30S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (215 aa) |
| | rpl44e | 50S ribosomal protein L44e; Binds to the 23S rRNA. (94 aa) |
| | nop10 | H/ACA RNA-protein complex component Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (59 aa) |
| | GQS_04105 | Signaling protein; COG1916 Uncharacterized homolog of PrgY (pheromone shutdown protein). (233 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (314 aa) |
| | tbp | TATA box-binding protein, transcription initiation factor TFIID (tbp); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (179 aa) |
| | GQS_04170 | Dinitrogenase iron-molybdenum cofactor, NIF B/Y/X related protein. (131 aa) |
| | GQS_04180 | Fe-S cluster containing protein, SufBD related (sufBD); COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component. (317 aa) |
| | GQS_04290 | Hypothetical protein; COG0731 Fe-S oxidoreductases. (316 aa) |
| | GQS_04305 | NADH oxidase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. (441 aa) |
| | rpl15e | COG1632 Ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (194 aa) |
| | fni | Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (372 aa) |
| | GQS_04555 | FAD dependent oxidoreductase; COG1251 NAD(P)H-nitrite reductase. (394 aa) |
| | GQS_04595 | NADH:polysulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. (445 aa) |
| | rpl40e | COG1552 Ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (52 aa) |
| | rps2P | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (201 aa) |
| | rps9p | COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (135 aa) |
| | rpl18e | COG1727 Ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa) |
| | rps4p | 30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa) |
| | rps13p | 30S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (149 aa) |
| | truB | H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (334 aa) |
| | rpl14e | COG2163 Ribosomal protein L14E/L6E/L27E; Belongs to the eukaryotic ribosomal protein eL14 family. (83 aa) |
| | rpl34e | COG2174 Ribosomal protein L34E; Belongs to the eukaryotic ribosomal protein eL34 family. (90 aa) |
| | rps5p | 30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (235 aa) |
| | rpl18p | 50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (201 aa) |
| | rpl19e | 50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (148 aa) |
| | rpl32e | COG1717 Ribosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (126 aa) |
| | rpl6p | 50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa) |
| | rps8p | 30S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rps14P | 30S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (56 aa) |
| | rpl5p | 50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (183 aa) |
| | rps4e | COG1471 Ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa) |
| | rpl24p | 50S ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit. (121 aa) |
| | rpl14p | 50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa) |
| | rps17p | 30S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (111 aa) |
| | rpl29 | COG0255 Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (66 aa) |
| | rps3p | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (210 aa) |
| | rpl22p | 50S ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (156 aa) |
| | rps19p | 30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (133 aa) |
| | rpl23 | 50S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl3p | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (347 aa) |
| | GQS_04890 | Hypothetical protein. (256 aa) |
| | rpl10e | COG0197 Ribosomal protein L16/L10E; Belongs to the universal ribosomal protein uL16 family. (182 aa) |
| | GQS_04920 | Serine--glyoxylate aminotransferase, class V; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. (384 aa) |
| | GQS_04980 | Cytochrome-c3 hydrogenase subunit gamma; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. (291 aa) |
| | GQS_05090 | Protein, conserved, containing ZPR1 zinc-finger domain; COG1779 C4-type Zn-finger protein. (224 aa) |
| | GQS_05120 | Putative RNA-associated protein; COG1500 Predicted exosome subunit. (236 aa) |
| | GQS_05135 | Hypothetical protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (149 aa) |
| | GQS_05255 | COG1011 Predicted hydrolase (HAD superfamily). (233 aa) |
| | GQS_05270 | COG0417 DNA polymerase elongation subunit (family B). (775 aa) |
| | GQS_05285 | Hypothetical protein. (205 aa) |
| | GQS_05305 | COG0648 Endonuclease IV. (281 aa) |
| | GQS_05355 | Replication factor A; COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins. (357 aa) |
| | ubiA | Prenyltransferase UbiA-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (276 aa) |
| | GQS_05380 | Hypothetical protein; COG1341 Predicted GTPase or GTP-binding protein. (325 aa) |
| | engB | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation. (209 aa) |
| | rps6e | COG2125 Ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family. (125 aa) |
| | GQS_05550 | Putative leucine aminopeptidase; COG2234 Predicted aminopeptidases. (562 aa) |
| | GQS_05605 | COG0681 Signal peptidase I. (354 aa) |
| | rps24e | COG2004 Ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (98 aa) |
| | taw1 | tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (333 aa) |
| | GQS_05665 | Hypothetical protein; COG1657 Squalene cyclase. (741 aa) |
| | cetZ | Cell division protein ftsZ-like 3; Involved in cell shape control; Belongs to the CetZ family. (384 aa) |
| | pdxS | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa) |
| | GQS_05880 | COG1239 Mg-chelatase subunit ChlI. (637 aa) |
| | GQS_05885 | COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases. (1252 aa) |
| | GQS_05980 | Hypothetical protein; COG1672 Predicted ATPase (AAA+ superfamily). (436 aa) |
| | GQS_05995 | COG1287 Uncharacterized membrane protein, required for N-linked glycosylation. (788 aa) |
| | GQS_06030 | Hypothetical protein; COG0714 MoxR-like ATPases. (306 aa) |
| | GQS_06090 | Oligosaccharyl transferase, STT3 subunit; COG1287 Uncharacterized membrane protein, required for N-linked glycosylation. (784 aa) |
| | GQS_06100 | Hypothetical protein. (144 aa) |
| | GQS_06195 | COG0297 Glycogen synthase. (450 aa) |
| | GQS_06250 | COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I. (271 aa) |
| | GQS_06285 | COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (334 aa) |
| | GQS_06290 | COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (334 aa) |
| | GQS_06305 | Pyruvate dehydrogenase, beta subunit; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (327 aa) |
| | GQS_06310 | COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (334 aa) |
| | priL | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (406 aa) |
| | priS | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (346 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (233 aa) |
| | GQS_06475 | alanyl-tRNA synthetase; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain. (407 aa) |
| | atpB | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (463 aa) |
| | atpF | V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (102 aa) |
| | GQS_06555 | COG1374 Protein involved in ribosomal biogenesis, contains PUA domain. (168 aa) |
| | GQS_06590 | Prokaryotic ATPase, AAA superfamily protein; COG1672 Predicted ATPase (AAA+ superfamily). (468 aa) |
| | GQS_06695 | Na+/H+ antiporter, napA type (napA); COG0475 Kef-type K+ transport systems, membrane components. (374 aa) |
| | GQS_06700 | NapA-type sodium/hydrogen antiporter; COG0475 Kef-type K+ transport systems, membrane components. (380 aa) |
| | GQS_06745 | Hypothetical protein; COG0170 Dolichol kinase. (208 aa) |
| | GQS_06750 | Hydrolase; COG1011 Predicted hydrolase (HAD superfamily). (231 aa) |
| | GQS_06760 | NapA-type sodium/hydrogen antiporter; COG0475 Kef-type K+ transport systems, membrane components. (391 aa) |
| | GQS_06770 | Cobalt/zinc/cadmium cation efflux pump protein; COG0053 Predicted Co/Zn/Cd cation transporters. (286 aa) |
| | sat | COG2046 ATP sulfurylase (sulfate adenylyltransferase); Belongs to the sulfate adenylyltransferase family. (379 aa) |
| | GQS_06890 | COG0644 Dehydrogenases (flavoproteins). (370 aa) |
| | GQS_06920 | Hypothetical protein; COG0714 MoxR-like ATPases. (317 aa) |
| | GQS_06980 | GTPase; COG1161 Predicted GTPases. (357 aa) |
| | GQS_07065 | Prokaryotic ATPase, AAA superfamily protein; COG1672 Predicted ATPase (AAA+ superfamily). (456 aa) |
| | GQS_07110 | RNase III inhibitor; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. (181 aa) |
| | radA | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (354 aa) |
| | cdc6 | Cell division control protein 6; Involved in regulation of DNA replication. (415 aa) |
| | GQS_07390 | Hypothetical protein. (94 aa) |
| | GQS_07605 | COG0621 2-methylthioadenine synthetase. (425 aa) |
| | GQS_07620 | COG0681 Signal peptidase I. (189 aa) |
| | GQS_07625 | Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain. (118 aa) |
| | GQS_07740 | COG0681 Signal peptidase I. (158 aa) |
| | GQS_07750 | Hypothetical protein; COG1672 Predicted ATPase (AAA+ superfamily). (360 aa) |
| | GQS_07785 | Helicase domain protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. (1155 aa) |
| | lig | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family. (559 aa) |
| | GQS_07940 | Oxidoreductase; COG1233 Phytoene dehydrogenase and related proteins. (420 aa) |
| | tfe | Transcription initiation factor E subunit alpha; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] (178 aa) |
| | GQS_08290 | moxR-type AAA ATPase, putative chaperone protein (moxR); COG0714 MoxR-like ATPases. (324 aa) |
| | GQS_08395 | Hypothetical protein. (137 aa) |
| | GQS_08420 | COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I. (205 aa) |
| | endA | tRNA-splicing endonuclease subunit alpha; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (171 aa) |
| | GQS_08505 | Replication factor C small subunit; COG0470 ATPase involved in DNA replication. (866 aa) |
| | rfcL | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (498 aa) |
| | GQS_08525 | Met-10 like-protein, putative SAM-dependent methyltransferase; COG2520 Predicted methyltransferase. (336 aa) |
| | radB | DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (224 aa) |
| | GQS_08620 | L-asparaginase; COG1446 Asparaginase. (306 aa) |
| | GQS_08680 | COG2131 Deoxycytidylate deaminase. (177 aa) |
| | GQS_08710 | ferredoxin-NADP(+) reductase subunit alpha; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. (280 aa) |
| | GQS_08735 | Short-chain alcohol dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (247 aa) |
| | GQS_08765 | Membrane protein, conserved; COG1657 Squalene cyclase. (589 aa) |
| | GQS_08820 | NADH oxidase (NOXase) (nox); COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. (439 aa) |
| | kptA | RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (194 aa) |
| | GQS_08840 | Hypothetical protein; COG4690 Dipeptidase. (424 aa) |
| | GQS_08990 | C/D box methylation guide ribonucleoprotein complex aNOP56 subunit; COG1498 Protein implicated in ribosomal biogenesis, Nop56p homolog. (425 aa) |
| | flpA | Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (226 aa) |
| | GQS_09005 | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa) |
| | GQS_09015 | Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon. (134 aa) |
| | GQS_09025 | N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (177 aa) |
| | GQS_09030 | COG1813 Predicted transcription factor, homolog of eukaryotic MBF1. (193 aa) |
| | tbp-2 | Transcription factor; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (190 aa) |
| | GQS_09045 | COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. (309 aa) |
| | GQS_09050 | Hypothetical protein; COG1672 Predicted ATPase (AAA+ superfamily). (368 aa) |
| | GQS_09125 | UbiA prenyltransferase family protein; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases. (269 aa) |
| | GQS_09150 | NapA-type sodium/hydrogen antiporter; COG0475 Kef-type K+ transport systems, membrane components. (382 aa) |
| | GQS_09210 | Prokaryotic ATPase, AAA superfamily protein; COG1672 Predicted ATPase (AAA+ superfamily). (313 aa) |
| | GQS_09220 | ferredoxin-NADP(+) reductase subunit alpha; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. (293 aa) |
| | hel308 | Ski2-like helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (726 aa) |
| | GQS_09395 | COG2016 Predicted RNA-binding protein (contains PUA domain). (172 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (215 aa) |
| | GQS_09470 | H/ACA RNA-protein complex component Gar1; COG3277 RNA-binding protein involved in rRNA processing. (106 aa) |
| | GQS_09485 | COG2036 Histones H3 and H4. (67 aa) |
| | rbcL | Ribulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (444 aa) |
| | rps17E | COG1383 Ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (67 aa) |
| | GQS_09580 | Hydroxypyruvate reductase (ttuD); COG2379 Putative glycerate kinase. (440 aa) |
| | GQS_09630 | Hypothetical protein. (140 aa) |
| | GQS_09650 | Prokaryotic ATPase, AAA superfamily protein; COG1672 Predicted ATPase (AAA+ superfamily). (452 aa) |
| | GQS_09730 | Hydrolase; COG1011 Predicted hydrolase (HAD superfamily). (235 aa) |
| | GQS_09780 | Acetyltransferase, GNAT family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (207 aa) |
| | GQS_09860 | COG2453 Predicted protein-tyrosine phosphatase. (150 aa) |
| | GQS_09870 | Phosphonate matabolism protein PhnP-like protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I. (249 aa) |
| | GQS_09965 | Hypothetical protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing. (292 aa) |
| | GQS_09970 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (562 aa) |
| | rpl31e | COG2097 Ribosomal protein L31E; Belongs to the ribosomal protein L31e family. (89 aa) |
| | rplX | COG2157 Ribosomal protein L20A (L18A). (76 aa) |
| | rps19e | 30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (150 aa) |
| | fen | Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (341 aa) |
| | GQS_10070 | Hypothetical protein. (106 aa) |
| | GQS_10090 | Hypothetical protein; COG1672 Predicted ATPase (AAA+ superfamily). (454 aa) |
| | GQS_10230 | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (406 aa) |
| | GQS_10275 | COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (281 aa) |
| | GQS_10350 | COG1199 Rad3-related DNA helicases. (671 aa) |
| | GQS_10380 | COG1215 Glycosyltransferases, probably involved in cell wall biogenesis. (414 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (238 aa) |
| | tmcA | ATPase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (810 aa) |
