(83 nodes) Actin cytoskeleton network (Aureobasidium subglaciale)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A074Y337	Uncharacterized protein. (142 aa)
	A0A074Y3C7	Uncharacterized protein. (322 aa)
	A0A074Y436	Glycoside hydrolase family 5 protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (389 aa)
	A0A074Y4U6	Uncharacterized protein. (428 aa)
	A0A074Y549	Glycoside hydrolase family 5 protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (502 aa)
	A0A074Y5E2	Uncharacterized protein. (658 aa)
	A0A074YD75	Uncharacterized protein. (116 aa)
	A0A074YE00	Carbohydrate-binding module family 24 protein. (635 aa)
	A0A074YE80	Glycoside hydrolase family 5 protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (462 aa)
	A0A074YF27	Glycoside hydrolase family 5 protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (417 aa)
	A0A074Y623	Uncharacterized protein. (407 aa)
	A0A074Y669	Uncharacterized protein. (1274 aa)
	A0A074Y6U5	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	A0A074Y760	Uncharacterized protein. (370 aa)
	A0A074Y868	SH3 domain-containing protein. (1239 aa)
	A0A074Y8Q4	Uncharacterized protein. (154 aa)
	A0A074Y8W3	ADF-H domain-containing protein. (153 aa)
	A0A074Y9U0	Glycoside hydrolase family 71 protein. (454 aa)
	A0A074Y9U1	Uncharacterized protein. (196 aa)
	A0A074YB29	IPPc domain-containing protein. (1167 aa)
	A0A074YB60	Uncharacterized protein. (658 aa)
	A0A074YBP2	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (702 aa)
	A0A074YCB1	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (187 aa)
	A0A074YCI0	VHS domain-containing protein. (510 aa)
	A0A074YFJ4	Uncharacterized protein. (590 aa)
	A0A074YGD6	Uncharacterized protein. (1057 aa)
	A0A074YGG0	Adenylyl cyclase-associated protein; Belongs to the CAP family. (559 aa)
	A0A074YF55	Uncharacterized protein. (1140 aa)
	A0A074YFE6	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1601 aa)
	A0A074YGP0	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
	A0A074YGS1	BAR domain-containing protein. (261 aa)
	A0A074YH17	Zn(2)-C6 fungal-type domain-containing protein. (510 aa)
	A0A074YHF7	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (318 aa)
	A0A074YHV2	DUF2013 domain-containing protein. (461 aa)
	A0A074YJK7	Uncharacterized protein. (577 aa)
	A0A074YJX1	Uncharacterized protein. (1430 aa)
	A0A074YK64	SH3 domain-containing protein. (1381 aa)
	A0A074YKT9	CRIB domain-containing protein. (778 aa)
	A0A074YL30	SH3 domain-containing protein. (401 aa)
	A0A074YL75	Uncharacterized protein. (173 aa)
	A0A074YM66	Uncharacterized protein. (583 aa)
	A0A074YPN6	Uncharacterized protein; Belongs to the actin family. (491 aa)
	A0A074YPP7	Uncharacterized protein. (101 aa)
	A0A074YPU4	WW domain-containing protein. (294 aa)
	A0A074YQ10	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (150 aa)
	A0A074YRI1	DH domain-containing protein. (1600 aa)
	A0A074YRM9	Uncharacterized protein. (80 aa)
	A0A074YRT9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (370 aa)
	A0A074YSH9	TYR_PHOSPHATASE_2 domain-containing protein. (638 aa)
	A0A074YSS3	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (189 aa)
	A0A074YST4	Uncharacterized protein. (205 aa)
	A0A074YSU8	Uncharacterized protein. (1614 aa)
	A0A074YT07	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (342 aa)
	A0A074YT52	WD_REPEATS_REGION domain-containing protein. (615 aa)
	A0A074YTK3	Uncharacterized protein. (320 aa)
	A0A074YVI5	ADF-H domain-containing protein. (115 aa)
	A0A074YVS3	BTB domain-containing protein. (378 aa)
	A0A074YW60	Uncharacterized protein. (1100 aa)
	A0A074YW83	Uncharacterized protein. (130 aa)
	A0A074YXD4	Uncharacterized protein; Belongs to the actin family. (428 aa)
	A0A074YXV9	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. (2159 aa)
	A0A074YYD4	Glycoside hydrolase family 5 protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (558 aa)
	A0A074YYK3	Uncharacterized protein. (1398 aa)
	A0A074Z1B6	Uncharacterized protein. (971 aa)
	A0A074Z334	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (283 aa)
	A0A074Z492	Glycoside hydrolase family 5 protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (417 aa)
	A0A074Z539	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (267 aa)
	A0A074Z728	Uncharacterized protein. (818 aa)
	A0A074Z746	Uncharacterized protein. (636 aa)
	A0A074Z9B2	Uncharacterized protein. (667 aa)
	A0A074ZC82	Glycoside hydrolase family 5 protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (397 aa)
	A0A074ZEG2	Coronin; Belongs to the WD repeat coronin family. (621 aa)
	A0A074ZGL6	RRN9 domain-containing protein. (744 aa)
	A0A074ZHI8	Uncharacterized protein. (781 aa)
	A0A074ZI86	Glycosyltransferase family 2 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1856 aa)
	A0A074ZJJ4	C2 domain-containing protein. (796 aa)
	A0A074ZKM2	Calponin-homology (CH) domain-containing protein. (637 aa)
	A0A074ZRJ9	Uncharacterized protein. (419 aa)
	A0A074XZ67	WH2 domain-containing protein. (456 aa)
	A0A074Y093	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (369 aa)
	A0A074Y0Y3	Uncharacterized protein. (226 aa)
	A0A074Y1I8	Uncharacterized protein. (399 aa)
	A0A074Y300	DUF2183 domain-containing protein. (338 aa)

Your Current Organism:

Aureobasidium subglaciale

NCBI taxonomy Id: 1043005
Other names: A. subglaciale EXF-2481, Aureobasidium pullulans var. subglaciale EXF-2481, Aureobasidium subglaciale EXF-2481

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A074XZ67	A0A074Y0Y3	WH2 domain-containing protein.	Uncharacterized protein.	0.623
A0A074XZ67	A0A074Y623	WH2 domain-containing protein.	Uncharacterized protein.	0.498
A0A074XZ67	A0A074Y669	WH2 domain-containing protein.	Uncharacterized protein.	0.623
A0A074XZ67	A0A074Y6U5	WH2 domain-containing protein.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	0.715
A0A074XZ67	A0A074Y760	WH2 domain-containing protein.	Uncharacterized protein.	0.649
A0A074XZ67	A0A074YB60	WH2 domain-containing protein.	Uncharacterized protein.	0.457
A0A074XZ67	A0A074YCB1	WH2 domain-containing protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.764
A0A074XZ67	A0A074YD75	WH2 domain-containing protein.	Uncharacterized protein.	0.649
A0A074XZ67	A0A074YF55	WH2 domain-containing protein.	Uncharacterized protein.	0.801
A0A074XZ67	A0A074YFJ4	WH2 domain-containing protein.	Uncharacterized protein.	0.995
A0A074XZ67	A0A074YGD6	WH2 domain-containing protein.	Uncharacterized protein.	0.783
A0A074XZ67	A0A074YGS1	WH2 domain-containing protein.	BAR domain-containing protein.	0.652
A0A074XZ67	A0A074YHF7	WH2 domain-containing protein.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.714
A0A074XZ67	A0A074YHV2	WH2 domain-containing protein.	DUF2013 domain-containing protein.	0.726
A0A074XZ67	A0A074YPN6	WH2 domain-containing protein.	Uncharacterized protein; Belongs to the actin family.	0.602
A0A074XZ67	A0A074YQ10	WH2 domain-containing protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.507
A0A074XZ67	A0A074YSS3	WH2 domain-containing protein.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.767
A0A074XZ67	A0A074YT07	WH2 domain-containing protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.870
A0A074XZ67	A0A074YTK3	WH2 domain-containing protein.	Uncharacterized protein.	0.649
A0A074XZ67	A0A074YVS3	WH2 domain-containing protein.	BTB domain-containing protein.	0.498