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ccmA ccmA DSC_09250 DSC_09250 ccmC ccmC ccmE ccmE DSC_09290 DSC_09290 DSC_09295 DSC_09295 DSC_09300 DSC_09300 DSC_09305 DSC_09305
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ccmACytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (241 aa)
DSC_09250Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (228 aa)
ccmCABC transporter heme permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (249 aa)
ccmECytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (149 aa)
DSC_09290C-type cytochrome biogenesis membrane protein; COG1138 Cytochrome c biogenesis factor. (640 aa)
DSC_09295Periplasmic protein thiol/disulfide oxidoreductase DsbE; COG0526 Thiol-disulfide isomerase and thioredoxins. (177 aa)
DSC_09300Cytochrome C biogenesis protein ccmh; Possible subunit of a heme lyase. (146 aa)
DSC_09305COG4235 Cytochrome c biogenesis factor. (337 aa)
Your Current Organism:
Pseudoxanthomonas spadix
NCBI taxonomy Id: 1045855
Other names: P. spadix BD-a59, Pseudoxanthomonas spadix BD-a59, Pseudoxanthomonas spadix str. BD-a59, Pseudoxanthomonas spadix strain BD-a59
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