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purU purU DSC_05865 DSC_05865 thrA thrA DSC_06835 DSC_06835 DSC_08965 DSC_08965 DSC_09780 DSC_09780 glnD glnD DSC_13185 DSC_13185 DSC_13450 DSC_13450
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (283 aa)
DSC_05865Bifunctional aspartate kinase/diaminopimelate decarboxylase protein; COG0527 Aspartokinases; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (865 aa)
thrABifunctional aspartokinase I/homoserine dehydrogenase I; COG0527 Aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. (827 aa)
DSC_06835COG2716 Glycine cleavage system regulatory protein. (186 aa)
DSC_08965Putative bifunctional chorismate mutase/prephenate dehydratase; COG1605 Chorismate mutase. (386 aa)
DSC_09780COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (412 aa)
glnDPII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (875 aa)
DSC_13185Guanosine polyphosphate pyrophosphohydrolase/synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (712 aa)
DSC_13450Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (721 aa)
Your Current Organism:
Pseudoxanthomonas spadix
NCBI taxonomy Id: 1045855
Other names: P. spadix BD-a59, Pseudoxanthomonas spadix BD-a59, Pseudoxanthomonas spadix str. BD-a59, Pseudoxanthomonas spadix strain BD-a59
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