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| | DSC_00090 | Serine 3-dehydrogenase; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa) |
| | DSC_00215 | COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa) |
| | DSC_00315 | Pteridine reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (246 aa) |
| | DSC_00360 | Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (607 aa) |
| | fabG | 3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (234 aa) |
| | DSC_00495 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (297 aa) |
| | DSC_00705 | GCN5-like N-acetyltransferase; COG1042 Acyl-CoA synthetase (NDP forming). (899 aa) |
| | DSC_00930 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (312 aa) |
| | DSC_01195 | Putative dehydrogenase, zinc-containing; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (336 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (494 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa) |
| | DSC_01870 | NAD(P)-dependent nucleotide sugar oxidoreductase; COG4091 Predicted homoserine dehydrogenase. (434 aa) |
| | DSC_01880 | Putative epimerase/dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases. (356 aa) |
| | gpsA | COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (340 aa) |
| | DSC_02265 | COG1064 Zn-dependent alcohol dehydrogenases. (361 aa) |
| | DSC_02455 | NAD-dependent epimerase/dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases. (328 aa) |
| | DSC_02520 | COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (349 aa) |
| | DSC_02535 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (301 aa) |
| | DSC_02540 | COG1004 Predicted UDP-glucose 6-dehydrogenase. (388 aa) |
| | DSC_02830 | COG1064 Zn-dependent alcohol dehydrogenases. (324 aa) |
| | cysG | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (483 aa) |
| | DSC_03750 | Short-chain dehydrogenase/reductase SDR; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa) |
| | DSC_03775 | NAD-dependent epimerase/dehydratase; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. (231 aa) |
| | DSC_03855 | COG1064 Zn-dependent alcohol dehydrogenases. (339 aa) |
| | DSC_04375 | Hypothetical protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (353 aa) |
| | DSC_04515 | COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (326 aa) |
| | DSC_04580 | Tropinone reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (258 aa) |
| | DSC_04615 | COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Belongs to the HIBADH-related family. (297 aa) |
| | ahcY | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (480 aa) |
| | DSC_05100 | Cation:proton antiporter; COG4651 Kef-type K+ transport system, predicted NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (584 aa) |
| | sucD | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | DSC_05820 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | thrA | Bifunctional aspartokinase I/homoserine dehydrogenase I; COG0527 Aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. (827 aa) |
| | DSC_06810 | Capsular polysaccharide biosynthesis protein I; COG0451 Nucleoside-diphosphate-sugar epimerases. (335 aa) |
| | DSC_06815 | Nucleotide sugar dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (426 aa) |
| | DSC_07015 | Putative gluconate 2-dehydrogenase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa) |
| | DSC_07035 | COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (587 aa) |
| | DSC_07535 | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (323 aa) |
| | fcl | NAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (314 aa) |
| | gmd | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (318 aa) |
| | DSC_08165 | 3-oxoacyl-[acyl-carrier-protein] reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (245 aa) |
| | DSC_08360 | acetoacetyl-CoA reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (248 aa) |
| | DSC_08375 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (250 aa) |
| | DSC_08435 | COG2902 NAD-specific glutamate dehydrogenase. (1659 aa) |
| | DSC_08485 | 3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (262 aa) |
| | DSC_08600 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (300 aa) |
| | DSC_08710 | COG0287 Prephenate dehydrogenase. (394 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (237 aa) |
| | DSC_08845 | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (327 aa) |
| | DSC_08850 | NAD-dependent epimerase/dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases. (323 aa) |
| | DSC_09020 | 3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa) |
| | DSC_09115 | Benzyl alcohol dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (361 aa) |
| | DSC_09350 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa) |
| | DSC_09370 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (304 aa) |
| | DSC_09715 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (366 aa) |
| | DSC_09765 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa) |
| | DSC_09780 | COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (412 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa) |
| | DSC_10275 | COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (608 aa) |
| | DSC_10330 | COG1250 3-hydroxyacyl-CoA dehydrogenase. (799 aa) |
| | DSC_10345 | Sugar epimerase; COG1086 Predicted nucleoside-diphosphate sugar epimerases. (635 aa) |
| | DSC_10650 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (279 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (402 aa) |
| | DSC_10815 | Putative S-(hydroxymethyl)glutathione dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (387 aa) |
| | DSC_11205 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (325 aa) |
| | DSC_11595 | NAD-binding 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (693 aa) |
| | fabG-2 | 3-ketoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa) |
| | DSC_11985 | Putative dehydrogenase/reductase protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa) |
| | DSC_12330 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (248 aa) |
| | DSC_12455 | Alcohol dehydrogenase GroES domain-containing protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (346 aa) |
| | tdh | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (340 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (426 aa) |
| | DSC_13035 | Pyridine nucleotide transhydrogenase; COG3288 NAD/NADP transhydrogenase alpha subunit. (364 aa) |
| | DSC_13135 | COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (260 aa) |
| | DSC_13635 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (272 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa) |
| | DSC_13865 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (288 aa) |
| | DSC_13950 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (259 aa) |
| | DSC_14175 | 3-oxoacyl-[acyl-carrier protein] reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (227 aa) |
| | DSC_14220 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (264 aa) |
| | DSC_14410 | 6-phosphogluconate dehydrogenase-like protein; COG1023 Predicted 6-phosphogluconate dehydrogenase. (301 aa) |
| | DSC_14425 | Hypothetical protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase. (298 aa) |
| | DSC_14825 | COG1062 Zn-dependent alcohol dehydrogenases, class III. (374 aa) |
| | benD | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa) |
| | DSC_14940 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (266 aa) |
| | DSC_15195 | COG0281 Malic enzyme. (764 aa) |
| | DSC_15425 | Sterol-4-alpha-carboxylate 3-dehydrogenase; COG0451 Nucleoside-diphosphate-sugar epimerases. (332 aa) |
| | DSC_15570 | Hypothetical protein; COG0451 Nucleoside-diphosphate-sugar epimerases. (323 aa) |
