node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ESN63375.1 | ESN63377.1 | Ser39006_00783 | Ser39006_00785 | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | KEGG: sulfur carrier protein ThiS. | 0.976 |
ESN63375.1 | ESN63378.1 | Ser39006_00783 | Ser39006_00786 | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | Hypothetical protein; KEGG: thiF, thiamin (thiazole moiety) biosynthesis protein. | 0.984 |
ESN63375.1 | moeB | Ser39006_00783 | Ser39006_03232 | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | Hypothetical protein; KEGG: moeB, molybdopterin synthase sulfurylase. | 0.640 |
ESN63375.1 | thiC | Ser39006_00783 | Ser39006_00788 | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | Hypothetical protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.986 |
ESN63375.1 | thiD | Ser39006_00783 | Ser39006_03577 | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | KEGG: phosphomethylpyrimidine kinase. | 0.528 |
ESN63375.1 | thiE | Ser39006_00783 | Ser39006_00787 | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | Hypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.983 |
ESN63375.1 | thiG | Ser39006_00783 | Ser39006_00784 | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | Hypothetical protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.998 |
ESN63375.1 | thiM | Ser39006_00783 | Ser39006_03578 | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.500 |
ESN63377.1 | ESN63375.1 | Ser39006_00785 | Ser39006_00783 | KEGG: sulfur carrier protein ThiS. | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | 0.976 |
ESN63377.1 | ESN63378.1 | Ser39006_00785 | Ser39006_00786 | KEGG: sulfur carrier protein ThiS. | Hypothetical protein; KEGG: thiF, thiamin (thiazole moiety) biosynthesis protein. | 0.998 |
ESN63377.1 | ESN64110.1 | Ser39006_00785 | Ser39006_01518 | KEGG: sulfur carrier protein ThiS. | KEGG: hypothetical protein. | 0.942 |
ESN63377.1 | ESN64179.1 | Ser39006_00785 | Ser39006_01587 | KEGG: sulfur carrier protein ThiS. | Hypothetical protein; KEGG: UBA/THIF-type NAD/FAD binding protein. | 0.692 |
ESN63377.1 | moeB | Ser39006_00785 | Ser39006_03232 | KEGG: sulfur carrier protein ThiS. | Hypothetical protein; KEGG: moeB, molybdopterin synthase sulfurylase. | 0.962 |
ESN63377.1 | thiC | Ser39006_00785 | Ser39006_00788 | KEGG: sulfur carrier protein ThiS. | Hypothetical protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.969 |
ESN63377.1 | thiD | Ser39006_00785 | Ser39006_03577 | KEGG: sulfur carrier protein ThiS. | KEGG: phosphomethylpyrimidine kinase. | 0.940 |
ESN63377.1 | thiE | Ser39006_00785 | Ser39006_00787 | KEGG: sulfur carrier protein ThiS. | Hypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.990 |
ESN63377.1 | thiG | Ser39006_00785 | Ser39006_00784 | KEGG: sulfur carrier protein ThiS. | Hypothetical protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
ESN63377.1 | thiI | Ser39006_00785 | Ser39006_01693 | KEGG: sulfur carrier protein ThiS. | Hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.759 |
ESN63377.1 | thiM | Ser39006_00785 | Ser39006_03578 | KEGG: sulfur carrier protein ThiS. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.823 |
ESN63378.1 | ESN63375.1 | Ser39006_00786 | Ser39006_00783 | Hypothetical protein; KEGG: thiF, thiamin (thiazole moiety) biosynthesis protein. | Hypothetical protein; KEGG: thiH, thiamine biosynthesis protein ThiH. | 0.984 |