Your Input: | |
| | ESN65210.1 | KEGG: metC, cystathionine beta-lyase. (420 aa) |
| | ESN65216.1 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1228 aa) |
| | metAS | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (309 aa) |
| | aroE | Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (275 aa) |
| | argH | KEGG: argininosuccinate lyase. (475 aa) |
| | argD-2 | Succinyldiaminopimelate transaminase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (407 aa) |
| | ESN65311.1 | KEGG: para-aminobenzoate synthase component II. (191 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (367 aa) |
| | ESN65411.1 | KEGG: 3-dehydroquinate synthase. (389 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (492 aa) |
| | ilvA | Hypothetical protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (514 aa) |
| | ilvD | KEGG: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (616 aa) |
| | ilvE | Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa) |
| | ESN65452.1 | Hypothetical protein; KEGG: ilvM, acetolactate synthase II, small subunit. (85 aa) |
| | ESN65453.1 | KEGG: acetolactate synthase 2 catalytic subunit. (555 aa) |
| | metF | KEGG: metF, 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (297 aa) |
| | metL | Hypothetical protein; KEGG: aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. (811 aa) |
| | ESN62874.1 | Hypothetical protein; KEGG: O-succinylhomoserine (thiol)-lyase. (386 aa) |
| | ESN62985.1 | KEGG: hypothetical protein. (348 aa) |
| | ESN62986.1 | Hypothetical protein; KEGG: dihydrodipicolinate synthase; Belongs to the DapA family. (316 aa) |
| | ESN62987.1 | Hypothetical protein; KEGG: L-fucose isomerase. (550 aa) |
| | argH-2 | KEGG: argH, argininosuccinate lyase. (457 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (257 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (334 aa) |
| | argE | KEGG: argE, acetylornithine deacetylase. (383 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (755 aa) |
| | ESN63170.1 | KEGG: serine O-acetyltransferase. (273 aa) |
| | ESN63222.1 | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (376 aa) |
| | ESN63241.1 | KEGG: avtA, valine--pyruvate transaminase. (418 aa) |
| | ESN63250.1 | Hypothetical protein; KEGG: dihydrodipicolinate synthase; Belongs to the DapA family. (303 aa) |
| | argG | KEGG: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (450 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (150 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa) |
| | ESN63574.1 | Hypothetical protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. (176 aa) |
| | serB | KEGG: serB, phosphoserine phosphatase. (325 aa) |
| | budA | KEGG: alpha-acetolactate decarboxylase. (260 aa) |
| | ESN63743.1 | KEGG: budB, acetolactate synthase, catabolic; Belongs to the TPP enzyme family. (595 aa) |
| | cysK | KEGG: cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (322 aa) |
| | ESN63938.1 | KEGG: tartrate dehydrogenase. (359 aa) |
| | argA | Amino-acid N-acetyltransferase; KEGG: N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. (441 aa) |
| | ESN64177.1 | KEGG: D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa) |
| | ESN64178.1 | Hypothetical protein; KEGG: histone acetyltransferase HPA2-like acetyltransferase. (127 aa) |
| | dapD | KEGG: dapD, 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (274 aa) |
| | ESN64235.1 | KEGG: argG2, argininosuccinate synthase. (409 aa) |
| | ESN64248.1 | Hypothetical protein; KEGG: vitamin-B12 independent methionine synthase. (373 aa) |
| | aroL | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (173 aa) |
| | ESN64265.1 | Hypothetical protein; KEGG: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. (368 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | ESN64486.1 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (350 aa) |
| | ESN64560.1 | KEGG: dihydrodipicolinate synthase. (294 aa) |
| | lysA | KEGG: diaminopimelate decarboxylase. (398 aa) |
| | ESN64616.1 | Cysteine synthase; KEGG: cysB2, cystathionine beta-synthase. (318 aa) |
| | arcA | KEGG: arginine deiminase. (406 aa) |
| | arcC | KEGG: arcC, carbamate kinase; Belongs to the carbamate kinase family. (304 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa) |
| | ESN64679.1 | Hypothetical protein; KEGG: C4-dicarboxylate anaerobic carrier-like protein. (467 aa) |
| | argR-2 | Hypothetical protein; Regulates arginine biosynthesis genes. (162 aa) |
| | ESN64762.1 | Hypothetical protein; KEGG: glycosyl transferase, family 3-like protein. (321 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (429 aa) |
| | hisI | Hypothetical protein; KEGG: hisI, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. (204 aa) |
| | hisF | Hypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamideisomerase; KEGG: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (245 aa) |
| | hisH | Hypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa) |
| | hisB | Histidinol-phosphatase; KEGG: imidazole glycerol-phosphate dehydratase/histidinol phosphatase; In the N-terminal section; belongs to the histidinol- phosphatase family. (355 aa) |
| | hisC | KEGG: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (436 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (299 aa) |
| | ESN65061.1 | Hypothetical protein; KEGG: aconitate hydratase domain-containing protein. (653 aa) |
| | ESN65114.1 | KEGG: putative GAF sensor protein. (177 aa) |
| | pabB | KEGG: para-aminobenzoate synthase subunit I. (463 aa) |
| | trpA | Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa) |
| | trpB | Tryptophan synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa) |
| | trpF | KEGG: trpC, Indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family. (468 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (332 aa) |
| | ESN61782.1 | Anthranilate synthase; KEGG: glutamine amidotransferase of anthranilate synthase; overlaps another CDS with the same product name. (192 aa) |
| | ESN61783.1 | KEGG: trpE, component I of anthranilate synthase; overlaps another CDS with the same product name. (520 aa) |
| | ESN61901.1 | Hypothetical protein; KEGG: HAD hydrolase, IB family. (221 aa) |
| | ESN62135.1 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (348 aa) |
| | aroK-2 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa) |
| | ESN62389.1 | Kynurenine--oxoglutarate transaminase; KEGG: aminotransferase. (387 aa) |
| | ESN62456.1 | Aspartate transaminase; KEGG: class I/II aminotransferase. (404 aa) |
| | ESN62484.1 | KEGG: putative semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa) |
| | pdxB | 4-phosphoerythronate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (378 aa) |
| | mnmC | Hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (672 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | ESN62520.1 | Cysteine synthase; KEGG: O-acetylhomoserine/O-acetylserine sulfhydrylase. (425 aa) |
| | ESN62544.1 | KEGG: aminotransferase. (411 aa) |
| | cysS | Cysteine--tRNA ligase; KEGG: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | ESN62634.1 | Hypothetical protein; KEGG: CoA-binding domain-containing protein. (137 aa) |
| | argC-2 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (345 aa) |
| | pheA | Hypothetical protein; KEGG: pheA, bifunctional chorismate mutase/prephenate dehydratase. (385 aa) |
| | tyrA | KEGG: chorismate mutase. (373 aa) |
| | ESN62841.1 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (357 aa) |
| | ESN61403.1 | D-amino-acid transaminase; KEGG: class IV aminotransferase. (304 aa) |
| | ESN61417.1 | Dihydroxy-acid dehydratase; KEGG: hypothetical protein; Belongs to the IlvD/Edd family. (655 aa) |
| | ESN61418.1 | KEGG: dihydrodipicolinate synthetase. (305 aa) |
| | ESN61431.1 | Hypothetical protein; KEGG: dihydrodipicolinate synthetase; Belongs to the DapA family. (294 aa) |
| | ESN61477.1 | KEGG: ilvH, acetolactate synthase 3 regulatory subunit; overlaps another CDS with the same product name. (164 aa) |
| | ESN61478.1 | KEGG: acetolactate synthase 3 catalytic subunit; overlaps another CDS with the same product name. (573 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (522 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (363 aa) |
| | leuC | Hypothetical protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa) |
| | leuD | Hypothetical protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa) |
| | ilvB | KEGG: acetolactate synthase, large subunit, biosynthetic type. (554 aa) |
| | ESN61492.1 | Hypothetical protein; KEGG: ilvN, acetolactate synthase small subunit. (97 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | ESN61534.1 | KEGG: thrC, threonine synthase. (429 aa) |
| | thrB | Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | ESN61536.1 | Hypothetical protein; KEGG: aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. (819 aa) |
| | ESN61547.1 | KEGG: D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (384 aa) |
| | ESN61571.1 | KEGG: lysC, aspartokinase III; Belongs to the aspartokinase family. (454 aa) |
| | ESN61596.1 | Glyoxylate reductase (NADP(+)); KEGG: D-isomer specific 2-hydroxyacid dehydrogenase. (308 aa) |
| | argF-2 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (336 aa) |
| | ESN61669.1 | Hypothetical protein; KEGG: homocysteine S-methyltransferase. (300 aa) |
| | hisC-2 | KEGG: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (370 aa) |
| | hisD-2 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (442 aa) |
| | lysA-2 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa) |
| | ESN61378.1 | KEGG: Prephenate dehydratase. (254 aa) |
| | ESN61381.1 | Aromatic-amino-acid transaminase; KEGG: aromatic amino acid aminotransferase. (397 aa) |
