STRINGSTRING
ESN63331.1 ESN63331.1 ESN64809.1 ESN64809.1 rhlE rhlE ybeY ybeY rsfS rsfS rlmH rlmH ESN64190.1 ESN64190.1 rlmM rlmM ESN64154.1 ESN64154.1 rlmF rlmF rsmC rsmC deaD deaD rbfA rbfA rimP rimP rlmE rlmE ESN63688.1 ESN63688.1 obgE obgE rlmG rlmG ESN63551.1 ESN63551.1 rsmI rsmI rlmC rlmC rlmJ rlmJ rsmJ rsmJ rph rph ESN63114.1 ESN63114.1 yihI yihI rsmG rsmG rsmD rsmD rpsS rpsS rsmB rsmB rlmB rlmB rlmD rlmD rsgA rsgA yqgF yqgF ESN61567.1 ESN61567.1 ksgA ksgA ESN61501.1 ESN61501.1 rsmH rsmH rimM rimM ESN62836.1 ESN62836.1 ESN62800.1 ESN62800.1 srmB srmB rnc rnc era era rlmN rlmN der der dbpA dbpA rne rne ESN62198.1 ESN62198.1 ESN62196.1 ESN62196.1 rlmL rlmL ESN62038.1 ESN62038.1 ESN61786.1 ESN61786.1 ESN61784.1 ESN61784.1 rplT rplT ESN65130.1 ESN65130.1 ESN65005.1 ESN65005.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ESN63331.1KEGG: hypothetical protein. (287 aa)
ESN64809.1Hypothetical protein; KEGG: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (258 aa)
rhlEHypothetical protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (454 aa)
ybeYHypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (159 aa)
rsfSHypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (105 aa)
rlmHHypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa)
ESN64190.1Hypothetical protein; KEGG: pseudouridine synthase. (256 aa)
rlmMHypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (367 aa)
ESN64154.1KEGG: hypothetical protein. (114 aa)
rlmFrRNA (adenine-N(6)-)-methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA. (310 aa)
rsmCrRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. (344 aa)
deaDHypothetical protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (624 aa)
rbfAHypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (132 aa)
rimPHypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (150 aa)
rlmEHypothetical protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (209 aa)
ESN63688.1KEGG: hypothetical protein. (97 aa)
obgEHypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (391 aa)
rlmGrRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (380 aa)
ESN63551.1KEGG: hypothetical protein. (277 aa)
rsmIHypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (289 aa)
rlmCHypothetical protein; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily. (379 aa)
rlmJHypothetical protein; Specifically methylates the adenine in position 2030 of 23S rRNA. (310 aa)
rsmJHypothetical protein; Specifically methylates the guanosine in position 1516 of 16S rRNA. (253 aa)
rphtRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (237 aa)
ESN63114.1KEGG: GTP-binding protein TypA. (608 aa)
yihIHypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. (174 aa)
rsmGHypothetical protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (206 aa)
rsmDrRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (191 aa)
rpsSHypothetical protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rsmBHypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (429 aa)
rlmBHypothetical protein; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily. (243 aa)
rlmDHypothetical protein; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (442 aa)
rsgAHypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (349 aa)
yqgFHypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (139 aa)
ESN61567.1Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (244 aa)
ksgAHypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (272 aa)
ESN61501.1Hypothetical protein; KEGG: pseudouridine synthase. (217 aa)
rsmHHypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (313 aa)
rimMHypothetical protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (182 aa)
ESN62836.1Hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (325 aa)
ESN62800.1Hypothetical protein; KEGG: ATP-dependent RNA helicase HrpB. (814 aa)
srmBHypothetical protein; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (441 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (226 aa)
eraHypothetical protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (301 aa)
rlmNHypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (390 aa)
derHypothetical protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (496 aa)
dbpAHypothetical protein; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. (459 aa)
rneHypothetical protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1071 aa)
ESN62198.1Hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (318 aa)
ESN62196.1KEGG: yceD, hypothetical protein. (173 aa)
rlmLrRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (705 aa)
ESN62038.1Hypothetical protein; KEGG: ATP-dependent helicase HrpA. (1295 aa)
ESN61786.1Hypothetical protein; KEGG: 23S rRNA pseudouridylate synthase B; Belongs to the pseudouridine synthase RsuA family. (290 aa)
ESN61784.1KEGG: yciV, hypothetical protein. (291 aa)
rplTHypothetical protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
ESN65130.1Hypothetical protein; KEGG: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (218 aa)
ESN65005.1KEGG: ribosomal-protein-S5-alanine N-acetyltransferase. (194 aa)
Your Current Organism:
Serratia sp. ATCC 39006
NCBI taxonomy Id: 104623
Other names: S. sp. ATCC 39006
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