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rplC rplC rplO rplO rpmD rpmD rplR rplR rplF rplF rplE rplE rplX rplX rplN rplN rpmC rpmC rplP rplP rplV rplV rplB rplB rplW rplW rplD rplD rpmE rpmE rpmH rpmH rpmB rpmB rplK rplK rplA rplA rplJ rplJ rplL rplL rplM rplM rplU rplU rpmA rpmA rplY rplY rpmI rpmI rplT rplT rpmF rpmF rplS rplS rplI rplI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rplCHypothetical protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa)
rplOHypothetical protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa)
rpmDKEGG: rpmD, 50S ribosomal protein L30. (59 aa)
rplRHypothetical protein; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa)
rplFHypothetical protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rplEHypothetical protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rplXHypothetical protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (104 aa)
rplNHypothetical protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa)
rpmCKEGG: 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (63 aa)
rplPHypothetical protein; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa)
rplVHypothetical protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (110 aa)
rplBHypothetical protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa)
rplWHypothetical protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa)
rplDHypothetical protein; Forms part of the polypeptide exit tunnel. (201 aa)
rpmErpmE, 50S ribosomal protein L31; Binds the 23S rRNA. (71 aa)
rpmHKEGG: rpmH, 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (46 aa)
rpmBKEGG: rpmB, 50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
rplKHypothetical protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)
rplAHypothetical protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa)
rplJHypothetical protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (165 aa)
rplLHypothetical protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (122 aa)
rplMHypothetical protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
rplUHypothetical protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa)
rpmAHypothetical protein; KEGG: rpmA, 50S ribosomal subunit protein L27; Belongs to the bacterial ribosomal protein bL27 family. (85 aa)
rplYHypothetical protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa)
rpmIKEGG: rpmI, 50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (65 aa)
rplTHypothetical protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
rpmFKEGG: rpmF, 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (56 aa)
rplSHypothetical protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa)
rplIHypothetical protein; Binds to the 23S rRNA. (150 aa)
Your Current Organism:
Serratia sp. ATCC 39006
NCBI taxonomy Id: 104623
Other names: S. sp. ATCC 39006
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