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| | ESN62557.1 | Hypothetical protein; KEGG: cpmB, carbapenem biosynthesis protein CpmB. (250 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (359 aa) |
| | ESN61293.1 | Hypothetical protein; KEGG: peptidyl-prolyl cis-trans isomerase. (206 aa) |
| | truD | Hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (345 aa) |
| | gmhA | Hypothetical protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (193 aa) |
| | nifM | Hypothetical protein; KEGG: nifM, peptidyl-prolyl cis-trans isomerase ppiD. (262 aa) |
| | nnrD | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (508 aa) |
| | pgi | KEGG: pgi, glucose-6-phosphate isomerase; Belongs to the GPI family. (550 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (220 aa) |
| | gpmB | KEGG: phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (216 aa) |
| | ESN61518.1 | KEGG: peptidylprolyl isomerase FKBP-type. (158 aa) |
| | surA | Hypothetical protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (430 aa) |
| | tyrA | KEGG: chorismate mutase. (373 aa) |
| | pheA | Hypothetical protein; KEGG: pheA, bifunctional chorismate mutase/prephenate dehydratase. (385 aa) |
| | ESN62836.1 | Hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (325 aa) |
| | hemL | KEGG: glutamate-1-semialdehyde aminotransferase. (426 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa) |
| | ESN62613.1 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa) |
| | fcl | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (321 aa) |
| | ESN62569.1 | KEGG: cpsB, mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (490 aa) |
| | ESN62568.1 | KEGG: manB, phosphomannomutase. (457 aa) |
| | ESN62547.1 | Hypothetical protein; KEGG: mandelate racemase/muconate lactonizing protein. (326 aa) |
| | ESN62502.1 | 3-hydroxybutyryl-CoA epimerase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family. In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (734 aa) |
| | truA | Hypothetical protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (274 aa) |
| | rpiB | KEGG: RpiB/LacA/LacB family sugar-phosphate isomerase. (151 aa) |
| | fabA | 3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa) |
| | ESN62198.1 | Hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (318 aa) |
| | ESN61823.1 | KEGG: mannose-6-phosphate isomerase, class I; Belongs to the mannose-6-phosphate isomerase type 1 family. (394 aa) |
| | araA | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (501 aa) |
| | topA | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] (865 aa) |
| | ESN61786.1 | Hypothetical protein; KEGG: 23S rRNA pseudouridylate synthase B; Belongs to the pseudouridine synthase RsuA family. (290 aa) |
| | trpF | KEGG: trpC, Indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family. (468 aa) |
| | topB | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] (640 aa) |
| | ESN61741.1 | Hypothetical protein; KEGG: aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (289 aa) |
| | ESN65185.1 | Hypothetical protein; KEGG: ycgM, isomerase/hydrolase. (218 aa) |
| | kduI | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (278 aa) |
| | ESN65130.1 | Hypothetical protein; KEGG: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (218 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamideisomerase; KEGG: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (245 aa) |
| | ESN64809.1 | Hypothetical protein; KEGG: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (258 aa) |
| | ESN64595.1 | Hypothetical protein; KEGG: aspartate racemase; Belongs to the aspartate/glutamate racemases family. (238 aa) |
| | galE | KEGG: UDP-galactose-4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa) |
| | galM | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (346 aa) |
| | gpmA | Bisphosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | ESN64444.1 | Hypothetical protein; KEGG: phosphoglucomutase. (547 aa) |
| | ESN64403.1 | Hypothetical protein; KEGG: aspartate/glutamate racemase; Belongs to the aspartate/glutamate racemases family. (231 aa) |
| | menF | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. (440 aa) |
| | gyrA | DNA topoisomerase (ATP-hydrolyzing); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent [...] (879 aa) |
| | ESN64304.1 | Hypothetical protein; KEGG: ppiD, peptidyl-prolyl cis-trans isomerase D. (625 aa) |
| | tig | Hypothetical protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (434 aa) |
| | queA | Hypothetical protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (355 aa) |
| | dxr | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). (399 aa) |
| | ESN64068.1 | KEGG: DNA topoisomerase III. (670 aa) |
| | idi | Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (181 aa) |
| | uxaC-2 | KEGG: glucuronate isomerase. (467 aa) |
| | iolB | Hypothetical protein; KEGG: Myo-inositol catabolism IolB domain-containing protein. (277 aa) |
| | ESN63775.1 | KEGG: phosphomannomutase. (453 aa) |
| | ESN63774.1 | KEGG: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. (476 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (186 aa) |
| | ESN63763.1 | Hypothetical protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (238 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (407 aa) |
| | lsrG | Hypothetical protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family. (96 aa) |
| | truB | Hypothetical protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (316 aa) |
| | glmM | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa) |
| | uxaC | KEGG: glucuronate isomerase. (469 aa) |
| | rhaA | KEGG: L-rhamnose isomerase. (418 aa) |
| | rhaM | Hypothetical protein; Involved in the anomeric conversion of L-rhamnose. (104 aa) |
| | ESN63574.1 | Hypothetical protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. (176 aa) |
| | maiA | KEGG: maleylacetoacetate isomerase. (214 aa) |
| | parC | DNA topoisomerase (ATP-hydrolyzing); Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (757 aa) |
| | parE | DNA topoisomerase (ATP-hydrolyzing); Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (631 aa) |
| | ESN63477.1 | Arabinose-5-phosphate isomerase; KEGG: KpsF/GutQ family protein. (328 aa) |
| | ESN63462.1 | KEGG: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | ESN63354.1 | 3-hydroxybutyryl-CoA epimerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (729 aa) |
| | xylA | KEGG: xylA, D-xylose isomerase; Belongs to the xylose isomerase family. (439 aa) |
| | ESN63202.1 | Hypothetical protein; KEGG: mandelate racemase/muconate lactonizing protein. (321 aa) |
| | hldD | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (310 aa) |
| | rbsD | Hypothetical protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (139 aa) |
| | gyrB | DNA topoisomerase (ATP-hydrolyzing); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent [...] (803 aa) |
| | ESN62967.1 | KEGG: gutQ, D-arabinose 5-phosphate isomerase. (321 aa) |
| | ESN62948.1 | KEGG: 4-oxalocrotonate tautomerase family protein. (65 aa) |
| | ESN62923.1 | KEGG: hydroxypyruvate isomerase; Belongs to the hyi family. (258 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (286 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (492 aa) |
| | ESN65443.1 | Hypothetical protein; KEGG: PpiC-type peptidyl-prolyl cis-trans isomerase. (111 aa) |
| | wecB | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (361 aa) |
| | dapF | Hypothetical protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa) |
| | ESN65339.1 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (192 aa) |
| | ESN65333.1 | Hypothetical protein; KEGG: enoyl-CoA hydratase/isomerase. (255 aa) |
| | ESN65286.1 | KEGG: FKBP-type peptidylprolyl isomerase. (196 aa) |
| | ESN65281.1 | KEGG: FKBP-type peptidyl-prolyl isomerase domain-containing protein. (273 aa) |
