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| | ESN61912.1 | KEGG: hypothetical protein. (380 aa) |
| | ESN64187.1 | KEGG: ygdH, hypothetical protein. (454 aa) |
| | tilS | Hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (421 aa) |
| | ppnP | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (94 aa) |
| | nrdR | Hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (149 aa) |
| | ESN64297.1 | KEGG: BolA family protein; Belongs to the BolA/IbaG family. (104 aa) |
| | ESN64303.1 | Hypothetical protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa) |
| | apt | Hypothetical protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa) |
| | adk | Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (235 aa) |
| | ESN64344.1 | KEGG: nrdB, ribonucleotide-diphosphate reductase subunit beta. (376 aa) |
| | ESN64345.1 | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (761 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (212 aa) |
| | purM | KEGG: phosphoribosylformylglycinamidine cyclo-ligase. (345 aa) |
| | purC | KEGG: phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (237 aa) |
| | ESN64421.1 | KEGG: hypothetical protein. (160 aa) |
| | ESN64427.1 | Hypothetical protein; KEGG: corC, Magnesium and cobalt efflux protein CorC. (292 aa) |
| | ESN64444.1 | Hypothetical protein; KEGG: phosphoglucomutase. (547 aa) |
| | ESN64507.1 | KEGG: yegH, hypothetical protein. (528 aa) |
| | ESN64561.1 | Ribosylpyrimidine nucleosidase; KEGG: Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. (317 aa) |
| | ESN64562.1 | Hypothetical protein; KEGG: Inosine/uridine-preferring nucleoside hydrolase; Belongs to the IUNH family. (316 aa) |
| | arcC | KEGG: arcC, carbamate kinase; Belongs to the carbamate kinase family. (304 aa) |
| | cyaB | Hypothetical protein; KEGG: adenylyl cyclase CyaB. (179 aa) |
| | ihfB | Hypothetical protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (94 aa) |
| | pyk | KEGG: pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa) |
| | purT | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (392 aa) |
| | ESN65073.1 | KEGG: pphA, serine/threonine protein phosphatase 1. (217 aa) |
| | guaD | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (452 aa) |
| | ESN65125.1 | KEGG: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa) |
| | ihfA | Hypothetical protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (98 aa) |
| | ESN65170.1 | KEGG: Integral membrane protein TerC. (517 aa) |
| | add | KEGG: adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (337 aa) |
| | ESN61833.1 | KEGG: hypothetical protein. (359 aa) |
| | prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | ychF | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa) |
| | ESN63894.1 | Hypothetical protein; KEGG: NUDIX hydrolase. (193 aa) |
| | ESN61917.1 | KEGG: gamma-glutamyltransferase. (533 aa) |
| | ttcA | Hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (314 aa) |
| | ESN62118.1 | KEGG: pyruvate kinase; Belongs to the pyruvate kinase family. (470 aa) |
| | ESN62131.1 | KEGG: hypothetical protein. (367 aa) |
| | ESN62181.1 | Hypothetical protein; KEGG: purine nucleoside phosphoramidase. (116 aa) |
| | ESN62213.1 | KEGG: hypothetical protein. (182 aa) |
| | ESN62330.1 | KEGG: Electron transfer flavoprotein alpha/beta-subunit. (254 aa) |
| | amn | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (490 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (505 aa) |
| | truA | Hypothetical protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (274 aa) |
| | ESN62513.1 | KEGG: hypothetical protein. (459 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (356 aa) |
| | ESN62622.1 | KEGG: exopolyphosphatase; Belongs to the GppA/Ppx family. (509 aa) |
| | ESN63386.1 | Hypothetical protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa) |
| | ESN63217.1 | KEGG: membrane protein. (246 aa) |
| | rph | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (237 aa) |
| | ESN63164.1 | Hypothetical protein; KEGG: polysaccharide deacetylase. (293 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | ESN63122.1 | Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (700 aa) |
| | gppA | Guanosine-5'-triphosphate,3'-diphosphate diphosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. (498 aa) |
| | ESN65405.1 | Hypothetical protein; KEGG: ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family. (183 aa) |
| | rdgB | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (200 aa) |
| | ESN65387.1 | KEGG: cyaA, adenylate cyclase; Belongs to the adenylyl cyclase class-1 family. (851 aa) |
| | ESN65302.1 | Hypothetical protein; KEGG: polysaccharide deacetylase. (284 aa) |
| | ESN65301.1 | Hypothetical protein; KEGG: polysaccharide deacetylase. (292 aa) |
| | purD | KEGG: phosphoribosylamine--glycine ligase; Belongs to the GARS family. (428 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (525 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa) |
| | ESN62706.1 | KEGG: hypothetical protein. (74 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1294 aa) |
| | tadA | Hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (168 aa) |
| | dgt | dGTPase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. (498 aa) |
| | ESN62813.1 | KEGG: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa) |
| | ESN61414.1 | Hypothetical protein; KEGG: decarboxylase; Belongs to the LOG family. (188 aa) |
| | guaC | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (375 aa) |
| | apaH | Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (282 aa) |
| | yjjX | Hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (179 aa) |
| | ESN61569.1 | KEGG: hypothetical protein; Belongs to the UPF0301 (AlgH) family. (187 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa) |
| | ESN61670.1 | KEGG: anaerobic ribonucleoside triphosphate reductase. (712 aa) |
| | gpt | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (152 aa) |
| | ESN61183.1 | N-carbamoyl-L-amino-acid hydrolase; KEGG: amidase, hydantoinase/carbamoylase family. (417 aa) |
| | ESN61184.1 | Serine--pyruvate transaminase; KEGG: aminotransferase class V. (414 aa) |
| | ESN61190.1 | KEGG: gamma-glutamyltransferase. (528 aa) |
| | ESN61192.1 | Hypothetical protein; KEGG: amidase. (466 aa) |
| | ESN61196.1 | Chitin deacetylase; KEGG: urate catabolism protein. (318 aa) |
| | ESN61197.1 | KEGG: Asp/Glu racemase. (245 aa) |
| | cysC | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (209 aa) |
| | cysN | Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (475 aa) |
| | cysD | KEGG: sulfate adenylyltransferase subunit 2. (302 aa) |
| | ESN61250.1 | Hypothetical protein; KEGG: mazG, nucleoside triphosphate pyrophosphohydrolase. (264 aa) |
| | ESN61251.1 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (744 aa) |
| | ESN61279.1 | KEGG: hypothetical protein. (441 aa) |
| | rdgB-2 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa) |
| | ESN61340.1 | Hypothetical protein; KEGG: monooxygenase FAD-binding. (384 aa) |
| | uraD | Hypothetical protein; KEGG: OHCU decarboxylase. (166 aa) |
| | uraH | Hypothetical protein; KEGG: hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (110 aa) |
| | ESN61380.1 | KEGG: hypothetical protein. (204 aa) |
| | purH | KEGG: purH, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (529 aa) |
| | ESN63399.1 | Hypothetical protein; KEGG: endonuclease/exonuclease/phosphatase. (381 aa) |
| | ESN63449.1 | Hypothetical protein; KEGG: HAD-superfamily hydrolase. (233 aa) |
| | ESN63451.1 | Hypothetical protein; KEGG: NUDIX hydrolase. (184 aa) |
| | ESN63512.1 | KEGG: nudF, ADP-ribose pyrophosphatase NudF. (210 aa) |
| | cpdA | Hypothetical protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (275 aa) |
| | ESN63544.1 | KEGG: 5'-nucleotidase. (319 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (407 aa) |
| | deoD | KEGG: purine nucleoside phosphorylase. (239 aa) |
| | cpdA-2 | Hypothetical protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (274 aa) |
| | ESN63812.1 | KEGG: membrane protein. (336 aa) |
| | ESN63852.1 | Hypothetical protein; KEGG: molybdenum cofactor biosynthesis protein F. (268 aa) |
