STRINGSTRING
msbB msbB lpxL lpxL kdsA kdsA rnfE rnfE ESN61777.1 ESN61777.1 hldE hldE ESN63186.1 ESN63186.1 ESN63185.1 ESN63185.1 ESN63184.1 ESN63184.1 ESN63183.1 ESN63183.1 ESN63182.1 ESN63182.1 rfaQ rfaQ ESN63180.1 ESN63180.1 wecF wecF ESN61107.1 ESN61107.1 ltrA ltrA ltrA-2 ltrA-2 ESN63187.1 ESN63187.1 ESN61219.1 ESN61219.1 gmhA gmhA kdsB kdsB lpxK lpxK lpxT lpxT lpxB lpxB lpxA lpxA lpxD lpxD ESN64034.1 ESN64034.1 ESN63883.1 ESN63883.1 lpxP lpxP ESN63799.1 ESN63799.1 ESN63793.1 ESN63793.1 diaA diaA ESN63478.1 ESN63478.1 ESN63477.1 ESN63477.1 ESN63476.1 ESN63476.1 ubiB ubiB ESN63249.1 ESN63249.1 ESN63179.1 ESN63179.1 hldD hldD ESN61735.1 ESN61735.1 ESN65272.1 ESN65272.1 arnT arnT ESN62985.1 ESN62985.1 ESN62967.1 ESN62967.1 ESN62226.1 ESN62226.1 lpxH lpxH ESN61393.1 ESN61393.1 lpxC lpxC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
msbBHypothetical protein; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (324 aa)
lpxLHypothetical protein; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa)
kdsA3-deoxy-8-phosphooctulonate synthase; KEGG: 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (284 aa)
rnfEHypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (231 aa)
ESN61777.1KEGG: outer membrane protein W. (211 aa)
hldEHypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (475 aa)
ESN63186.1Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (425 aa)
ESN63185.1Hypothetical protein; KEGG: group 1 glycosyl transferase. (376 aa)
ESN63184.1Hypothetical protein; KEGG: ADP-heptose--lipooligosaccharide heptosyltransferase II. (368 aa)
ESN63183.1Hypothetical protein; KEGG: O-antigen polymerase. (401 aa)
ESN63182.1Hypothetical protein; KEGG: glycosyl transferase group 1. (373 aa)
rfaQHypothetical protein; KEGG: lipopolysaccharide heptosyltransferase III. (361 aa)
ESN63180.1Hypothetical protein; KEGG: ADP-heptose:LPS heptosyl transferase I. (323 aa)
wecFHypothetical protein; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. (361 aa)
ESN61107.1RNA-directed DNA polymerase; KEGG: reverse transcriptase. (317 aa)
ltrAHypothetical protein; KEGG: RNA-directed DNA polymerase. (462 aa)
ltrA-2Hypothetical protein; KEGG: RNA-directed DNA polymerase. (462 aa)
ESN63187.1Hypothetical protein; KEGG: glycosyl transferase family 2. (258 aa)
ESN61219.1Hypothetical protein; KEGG: D,D-heptose 1,7-bisphosphate phosphatase. (188 aa)
gmhAHypothetical protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (193 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (250 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (336 aa)
lpxTHypothetical protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (243 aa)
lpxBLipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa)
lpxAAcyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa)
lpxDHypothetical protein; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (340 aa)
ESN64034.1KEGG: hypothetical protein. (328 aa)
ESN63883.1Ribonuclease H; KEGG: reverse transcriptase. (573 aa)
lpxPHypothetical protein; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. (307 aa)
ESN63799.1Hypothetical protein; KEGG: glycosyl transferase group 1. (372 aa)
ESN63793.1Hypothetical protein; KEGG: glycosyl transferase family protein. (304 aa)
diaAHypothetical protein; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. (196 aa)
ESN63478.1Hypothetical protein; KEGG: calcium/sodium:proton antiporter. (320 aa)
ESN63477.1Arabinose-5-phosphate isomerase; KEGG: KpsF/GutQ family protein. (328 aa)
ESN63476.13-deoxy-manno-octulosonate-8-phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (188 aa)
ubiBHypothetical protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (545 aa)
ESN63249.1KEGG: hypothetical protein. (333 aa)
ESN63179.1Hypothetical protein; KEGG: rfaF, ADP-heptose--LPS heptosyltransferase. (350 aa)
hldDADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (310 aa)
ESN61735.1KEGG: ycgB, hypothetical protein. (511 aa)
ESN65272.1KEGG: yjdB, hypothetical protein. (548 aa)
arnTHypothetical protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. (549 aa)
ESN62985.1KEGG: hypothetical protein. (348 aa)
ESN62967.1KEGG: gutQ, D-arabinose 5-phosphate isomerase. (321 aa)
ESN62226.1Hypothetical protein; KEGG: beta-D-1,6 glucosyltransferase. (810 aa)
lpxHHypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (240 aa)
ESN61393.1Hypothetical protein; KEGG: RNA-directed DNA polymerase. (115 aa)
lpxCHypothetical protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa)
Your Current Organism:
Serratia sp. ATCC 39006
NCBI taxonomy Id: 104623
Other names: S. sp. ATCC 39006
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