STRINGSTRING
ddl ddl ESN63686.1 ESN63686.1 murB murB ESN63452.1 ESN63452.1 murA murA murF murF mraY mraY murD murD murG murG murC murC ddl-2 ddl-2 murE murE ftsI ftsI mpl mpl uppP uppP ESN65046.1 ESN65046.1 ESN64892.1 ESN64892.1 ESN63061.1 ESN63061.1 ESN64872.1 ESN64872.1 ESN64754.1 ESN64754.1 mrcB mrcB mrdA mrdA ESN64411.1 ESN64411.1 ESN64396.1 ESN64396.1 uppS uppS mtgA mtgA ESN61446.1 ESN61446.1 ESN63861.1 ESN63861.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (365 aa)
ESN63686.1Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: hypothetical protein. (477 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (344 aa)
ESN63452.1Peptidoglycan glycosyltransferase; KEGG: mrcA, penicillin-binding protein 1A (PBP1A). (852 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (453 aa)
mraYHypothetical protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murDUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (437 aa)
murGHypothetical protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (363 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (486 aa)
ddl-2D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (306 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa)
ftsIPeptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (587 aa)
mplUDP-N-acetylmuramate--L-alanine ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (460 aa)
uppPHypothetical protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (272 aa)
ESN65046.1Hypothetical protein; KEGG: biotin carboxylase. (419 aa)
ESN64892.1Hypothetical protein; KEGG: N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD. (279 aa)
ESN63061.1KEGG: lipoprotein. (191 aa)
ESN64872.1KEGG: beta-lactamase; Belongs to the peptidase S11 family. (404 aa)
ESN64754.1Hypothetical protein; KEGG: pbpG, D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (320 aa)
mrcBPeptidoglycan glycosyltransferase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (833 aa)
mrdAPeptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (634 aa)
ESN64411.1Beta-lactamase; KEGG: D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (403 aa)
ESN64396.1Hypothetical protein; KEGG: D,D-carboxypeptidase-related protein. (224 aa)
uppSDi-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (253 aa)
mtgAHypothetical protein; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (243 aa)
ESN61446.1Hypothetical protein; KEGG: N-acetyl-anhydromuranmyl-L-alanine amidase. (183 aa)
ESN63861.1Hypothetical protein; KEGG: PA-phosphatase-like phosphoesterase. (197 aa)
Your Current Organism:
Serratia sp. ATCC 39006
NCBI taxonomy Id: 104623
Other names: S. sp. ATCC 39006
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