STRINGSTRING
ESN63853.1 ESN63853.1 nifJ nifJ grcA grcA ESN63743.1 ESN63743.1 budA budA ESN63354.1 ESN63354.1 ESN65453.1 ESN65453.1 ESN65452.1 ESN65452.1 ESN64390.1 ESN64390.1 ESN64568.1 ESN64568.1 ESN64547.1 ESN64547.1 ESN62561.1 ESN62561.1 ESN62502.1 ESN62502.1 ESN62557.1 ESN62557.1 ilvB ilvB ESN63901.1 ESN63901.1 frdA frdA ESN63984.1 ESN63984.1 ESN64388.1 ESN64388.1 ESN64479.1 ESN64479.1 ESN64459.1 ESN64459.1 sdhB sdhB sdhA sdhA mhpF mhpF sdhD sdhD ESN61477.1 ESN61477.1 ESN61478.1 ESN61478.1 ESN62425.1 ESN62425.1 ESN62334.1 ESN62334.1 ESN62007.1 ESN62007.1 gabD gabD ESN61760.1 ESN61760.1 nifJ-2 nifJ-2 pflB pflB ESN64672.1 ESN64672.1 gabT gabT ESN61492.1 ESN61492.1 nifJ-3 nifJ-3 ESN61635.1 ESN61635.1 ESN61647.1 ESN61647.1 frdC frdC frdD frdD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ESN63853.13-hydroxybutyrate dehydrogenase; KEGG: 3-oxoacyl-(acyl-carrier-protein) reductase. (264 aa)
nifJPyruvate dehydrogenase (NADP(+)); KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase. (1177 aa)
grcAHypothetical protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. (127 aa)
ESN63743.1KEGG: budB, acetolactate synthase, catabolic; Belongs to the TPP enzyme family. (595 aa)
budAKEGG: alpha-acetolactate decarboxylase. (260 aa)
ESN63354.13-hydroxybutyryl-CoA epimerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (729 aa)
ESN65453.1KEGG: acetolactate synthase 2 catalytic subunit. (555 aa)
ESN65452.1Hypothetical protein; KEGG: ilvM, acetolactate synthase II, small subunit. (85 aa)
ESN64390.1KEGG: 3-oxoacid CoA-transferase subunit A; overlaps another CDS with the same product name. (218 aa)
ESN64568.1Formate C-acetyltransferase; KEGG: hypothetical protein. (811 aa)
ESN64547.1KEGG: acetoin reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
ESN62561.1Succinate-semialdehyde dehydrogenase (NAD(P)(+)); KEGG: NAD-dependent aldehyde dehydrogenase. (463 aa)
ESN62502.13-hydroxybutyryl-CoA epimerase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family. In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (734 aa)
ESN62557.1Hypothetical protein; KEGG: cpmB, carbapenem biosynthesis protein CpmB. (250 aa)
ilvBKEGG: acetolactate synthase, large subunit, biosynthetic type. (554 aa)
ESN63901.1Hypothetical protein; KEGG: Dyp-type peroxidase family. (299 aa)
frdASuccinate dehydrogenase; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. (598 aa)
ESN63984.1KEGG: glutamate decarboxylase; Belongs to the group II decarboxylase family. (460 aa)
ESN64388.1KEGG: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
ESN64479.1KEGG: betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (491 aa)
ESN64459.1Hypothetical protein; KEGG: sdhC, succinate dehydrogenase cytochrome b556 large membrane subunit. (125 aa)
sdhBHypothetical protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
sdhASuccinate dehydrogenase (ubiquinone); Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. (588 aa)
mhpFAcetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (316 aa)
sdhDKEGG: sdhB, succinate dehydrogenase, FeS subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
ESN61477.1KEGG: ilvH, acetolactate synthase 3 regulatory subunit; overlaps another CDS with the same product name. (164 aa)
ESN61478.1KEGG: acetolactate synthase 3 catalytic subunit; overlaps another CDS with the same product name. (573 aa)
ESN62425.1KEGG: 3-hydroxyacyl-CoA dehydrogenase. (282 aa)
ESN62334.1Hypothetical protein; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (531 aa)
ESN62007.1KEGG: 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa)
gabDKEGG: succinic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (486 aa)
ESN61760.1KEGG: bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (899 aa)
nifJ-2Pyruvate dehydrogenase (NADP(+)); KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase. (1201 aa)
pflBKEGG: formate acetyltransferase. (760 aa)
ESN64672.1Hypothetical protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (431 aa)
gabTKEGG: gabT3, 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (438 aa)
ESN61492.1Hypothetical protein; KEGG: ilvN, acetolactate synthase small subunit. (97 aa)
nifJ-3Pyruvate dehydrogenase (NADP(+)); KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase. (1201 aa)
ESN61635.1Hypothetical protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (421 aa)
ESN61647.1Succinate dehydrogenase; KEGG: fumarate reductase iron-sulfur subunit; overlaps another CDS with the same product name; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
frdCHypothetical protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
frdDHypothetical protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (118 aa)
Your Current Organism:
Serratia sp. ATCC 39006
NCBI taxonomy Id: 104623
Other names: S. sp. ATCC 39006
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