STRINGSTRING
ESN64914.1 ESN64914.1 nikR nikR glpX glpX pfkA pfkA viaA viaA ppc ppc ESN63222.1 ESN63222.1 ESN63494.1 ESN63494.1 ESN63519.1 ESN63519.1 ESN63520.1 ESN63520.1 serB serB mdh mdh lsrF lsrF acs acs pigC pigC ESN64177.1 ESN64177.1 gpmA gpmA ESN64599.1 ESN64599.1 ESN64600.1 ESN64600.1 ESN64617.1 ESN64617.1 ESN64618.1 ESN64618.1 ESN64627.1 ESN64627.1 ESN64736.1 ESN64736.1 ESN64805.1 ESN64805.1 fghA fghA ESN64863.1 ESN64863.1 dmsD dmsD serC serC ESN64988.1 ESN64988.1 ESN65002.1 ESN65002.1 ESN65031.1 ESN65031.1 ESN61701.1 ESN61701.1 ESN61841.1 ESN61841.1 ESN62133.1 ESN62133.1 eno eno ESN62401.1 ESN62401.1 ESN62404.1 ESN62404.1 fdxH fdxH fdnG fdnG hybD hybD ESN62420.1 ESN62420.1 ackA ackA ESN62463.1 ESN62463.1 glyA glyA ESN61432.1 ESN61432.1 gpmB gpmB ESN61547.1 ESN61547.1 ESN61558.1 ESN61558.1 fbp fbp ESN61136.1 ESN61136.1 eno-2 eno-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ESN64914.1Trimethylamine-N-oxide reductase (cytochrome c); KEGG: anaerobic dimethyl sulfoxide reductase subunit A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (813 aa)
nikRPutative transcriptional regulator, CopG family; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel. (132 aa)
glpXFructose-bisphosphatase; KEGG: glpX, Fructose-1,6-bisphosphatase, GlpX type. (336 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
viaAKEGG: VWA containing CoxE family protein. (491 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (879 aa)
ESN63222.1Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (376 aa)
ESN63494.1KEGG: hypothetical protein. (136 aa)
ESN63519.1KEGG: ketose-bisphosphate aldolase. (286 aa)
ESN63520.1KEGG: sugar-bisphosphate aldolase. (283 aa)
serBKEGG: serB, phosphoserine phosphatase. (325 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
lsrFHypothetical protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family. (291 aa)
acsAcetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (652 aa)
pigCPyruvate, water dikinase, Phosphoenolpyruvate--protein phosphotransferase; Involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (MAP), one of the terminal products involved in the biosynthesis of the red antibiotic prodigiosin (Pig). Catalyzes the transfer of 2-methyl-3- n-amyl-pyrrole (MAP) to 4-methoxy-2,2'-bipyrrole-5-carbaldehyde (MBC) to yield prodigiosin; Belongs to the PigC family. (890 aa)
ESN64177.1KEGG: D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
gpmABisphosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)
ESN64599.1Nitrate reductase; KEGG: fdhF, formate dehydrogenase H; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (716 aa)
ESN64600.1Hypothetical protein; KEGG: hydN, formate dehydrogenase-H. (180 aa)
ESN64617.1Hypothetical protein; KEGG: hycI, hydrogenase 3 maturation protease. (149 aa)
ESN64618.1Hypothetical protein; KEGG: formate hydrogenlyase maturation HycH. (134 aa)
ESN64627.1Hypothetical protein; KEGG: 4Fe-4S ferredoxin. (208 aa)
ESN64736.1Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (316 aa)
ESN64805.1Hypothetical protein; KEGG: glutathione-dependent formaldehyde-activating protein. (172 aa)
fghAS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (279 aa)
ESN64863.1Hypothetical protein; KEGG: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (373 aa)
dmsDHypothetical protein; Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding- maturation pathway for the substrate protein. (204 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
ESN64988.1Hypothetical protein; KEGG: glutathione-dependent formaldehyde-activating protein. (134 aa)
ESN65002.1Hypothetical protein; KEGG: cytoplasmic chaperone TorD family protein. (193 aa)
ESN65031.1Putative transcriptional regulator, RpiR family; KEGG: yebK, DNA-binding transcriptional regulator. (289 aa)
ESN61701.1KEGG: phage-associated protein. (463 aa)
ESN61841.1KEGG: glyA, serine hydroxymethyltransferase. (421 aa)
ESN62133.1Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (428 aa)
ESN62401.1Putative transcriptional regulator, RpiR family; KEGG: transcriptional regulator of D-allose utilization. (292 aa)
ESN62404.1Hypothetical protein; KEGG: formate dehydrogenase subunit gamma. (211 aa)
fdxHHypothetical protein; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (306 aa)
fdnGNitrate reductase; KEGG: formate dehydrogenase subunit alpha. (1016 aa)
hybDHypothetical protein; KEGG: hydrogenase expression/formation protein. (166 aa)
ESN62420.1KEGG: hydrogenase 2 protein HybA. (338 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
ESN62463.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (712 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
ESN61432.1Glyoxylate reductase; KEGG: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (316 aa)
gpmBKEGG: phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (216 aa)
ESN61547.1KEGG: D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa)
ESN61558.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
fbpFructose-bisphosphatase; KEGG: fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family. (334 aa)
ESN61136.1KEGG: hypothetical protein. (483 aa)
eno-2Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (433 aa)
Your Current Organism:
Serratia sp. ATCC 39006
NCBI taxonomy Id: 104623
Other names: S. sp. ATCC 39006
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