STRINGSTRING
dnaA dnaA wecC wecC TC41_0060 TC41_0060 TC41_0081 TC41_0081 mcp mcp cheY cheY cheA cheA TC41_0147 TC41_0147 TC41_0148 TC41_0148 sfcA sfcA kdpE kdpE kdpD kdpD kdpA kdpA kdpB kdpB kdpC kdpC kdpD-2 kdpD-2 TC41_0413 TC41_0413 rpoN rpoN liaS liaS nreC nreC motA motA desK desK TC41_0623 TC41_0623 TC41_0630 TC41_0630 yesN yesN TC41_0884 TC41_0884 TC41_0890 TC41_0890 cheY-2 cheY-2 cheB cheB cheA-2 cheA-2 cheW cheW glnA glnA glnA-2 glnA-2 cheR cheR TC41_1619 TC41_1619 resE resE resD resD spo0A spo0A pstS pstS cydB cydB cydA cydA kinA kinA atoB-3 atoB-3 TC41_2258 TC41_2258 sfcA-2 sfcA-2 baeS baeS yesM yesM TC41_2552 TC41_2552 TC41_2587 TC41_2587 mcp-2 mcp-2 TC41_2729 TC41_2729 TC41_2759 TC41_2759 TC41_2767 TC41_2767 fliC fliC TC41_2859 TC41_2859 phoR phoR phoB phoB wecB wecB spo0F spo0F glnB glnB TC41_3279 TC41_3279 vicK vicK vicR vicR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (454 aa)
wecCNucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (455 aa)
TC41_0060Histidine kinase. (369 aa)
TC41_0081PAS/PAC sensor signal transduction histidine kinase. (565 aa)
mcpMethyl-accepting chemotaxis sensory transducer. (594 aa)
cheYResponse regulator receiver protein. (119 aa)
cheACheA signal transduction histidine kinase. (665 aa)
TC41_0147CheW protein. (155 aa)
TC41_0148Methyl-accepting chemotaxis sensory transducer. (381 aa)
sfcAMalate dehydrogenase (oxaloacetate- decarboxylating). (503 aa)
kdpETwo component transcriptional regulator, winged helix family. (232 aa)
kdpDSensor kinase subunit kdpD. (487 aa)
kdpAPotassium-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (562 aa)
kdpBK+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (683 aa)
kdpCPotassium-transporting ATPase; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (203 aa)
kdpD-2Osmosensitive K channel His kinase sensor. (734 aa)
TC41_0413Type IV pilin. (175 aa)
rpoNRNA polymerase, sigma 54 subunit, RpoN. (421 aa)
liaSPAS/PAC sensor signal transduction histidine kinase. (345 aa)
nreCTwo component transcriptional regulator, LuxR family. (225 aa)
motAMotA/TolQ/ExbB proton channel. (266 aa)
desKHistidine kinase. (351 aa)
TC41_0623Two component transcriptional regulator, LuxR family. (188 aa)
TC41_0630Cytochrome oxidase assembly. (327 aa)
yesNTwo component transcriptional regulator, AraC family. (277 aa)
TC41_0884Transcriptional regulator, AraC family. (423 aa)
TC41_0890Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (139 aa)
cheY-2Response regulator receiver protein. (119 aa)
cheBCheB methylesterase. (199 aa)
cheA-2CheA signal transduction histidine kinase. (664 aa)
cheWCheW protein. (154 aa)
glnAGlutamine synthetase, type I. (445 aa)
glnA-2Glutamine synthetase, type I. (473 aa)
cheRMCP methyltransferase, CheR-type. (247 aa)
TC41_1619Peptidase S1 and S6 chymotrypsin/Hap. (233 aa)
resEPAS/PAC sensor signal transduction histidine kinase. (645 aa)
resDTwo component transcriptional regulator, winged helix family. (233 aa)
spo0ASporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (262 aa)
pstSPhosphate ABC transporter, periplasmic phosphate- binding protein; Belongs to the PstS family. (375 aa)
cydBCytochrome d ubiquinol oxidase, subunit II. (340 aa)
cydACytochrome bd ubiquinol oxidase subunit I. (467 aa)
kinAPAS/PAC sensor signal transduction histidine kinase. (494 aa)
atoB-3acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
TC41_2258Methyl-accepting chemotaxis sensory transducer. (588 aa)
sfcA-2Malate dehydrogenase (oxaloacetate- decarboxylating). (474 aa)
baeSHistidine kinase. (429 aa)
yesMHypothetical protein. (321 aa)
TC41_2552Response regulator receiver protein. (256 aa)
TC41_2587Putative methyl-accepting chemotaxis sensory transducer. (371 aa)
mcp-2Methyl-accepting chemotaxis sensory transducer. (422 aa)
TC41_2729Peptidase S1 and S6 chymotrypsin/Hap. (435 aa)
TC41_2759Glutamine synthetase catalytic region. (444 aa)
TC41_2767Glycoside hydrolase family 9. (537 aa)
fliCFlagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (284 aa)
TC41_2859Putative RNA polymerase, sigma 28 subunit, FliA/WhiG family. (156 aa)
phoRPAS/PAC sensor signal transduction histidine kinase. (429 aa)
phoBTwo component transcriptional regulator, winged helix family. (236 aa)
wecBUDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (384 aa)
spo0FResponse regulator receiver protein. (125 aa)
glnBNitrogen regulatory protein P-II; Belongs to the P(II) protein family. (121 aa)
TC41_3279Peptidase S1 and S6 chymotrypsin/Hap. (398 aa)
vicKPAS/PAC sensor signal transduction histidine kinase. (588 aa)
vicRTwo component transcriptional regulator, winged helix family. (230 aa)
Your Current Organism:
Alicyclobacillus acidocaldarius Tc41
NCBI taxonomy Id: 1048834
Other names: A. acidocaldarius subsp. acidocaldarius Tc-4-1, Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1, Alicyclobacillus acidocaldarius subsp. acidocaldarius str. Tc-4-1, Alicyclobacillus acidocaldarius subsp. acidocaldarius strain Tc-4-1
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