STRINGSTRING
GNL3 GNL3 D7B24_004269 D7B24_004269 ENP1 ENP1 D7B24_003411 D7B24_003411 D7B24_004397 D7B24_004397 D7B24_003851 D7B24_003851 D7B24_004072 D7B24_004072 SPB1 SPB1 D7B24_002894 D7B24_002894 UTP11 UTP11 D7B24_002846 D7B24_002846 PAK1IP1 PAK1IP1 D7B24_002946 D7B24_002946 D7B24_003315 D7B24_003315 D7B24_002405 D7B24_002405 ROK1 ROK1 ERB1 ERB1 SDAD1 SDAD1 NLE1 NLE1 D7B24_002287 D7B24_002287 RRP8 RRP8 D7B24_003385 D7B24_003385 NOP2 NOP2 D7B24_001770 D7B24_001770 D7B24_002099 D7B24_002099 TTC27 TTC27 GTPBP4 GTPBP4 MRTO4 MRTO4 D7B24_001246 D7B24_001246 D7B24_001034 D7B24_001034 NOP7 NOP7 DUSP12 DUSP12 D7B24_002945 D7B24_002945 GAR1_1 GAR1_1 DNAJC21 DNAJC21 RRP5 RRP5 EMG1 EMG1 D7B24_000800 D7B24_000800 NCS6 NCS6 D7B24_002053 D7B24_002053 WDR4 WDR4 SGD1 SGD1 D7B24_000798 D7B24_000798 YTM1 YTM1 IMP3 IMP3 RPS7 RPS7 KRE33 KRE33 D7B24_009589 D7B24_009589 D7B24_009389 D7B24_009389 D7B24_009085 D7B24_009085 D7B24_008935 D7B24_008935 D7B24_009062 D7B24_009062 NOL6 NOL6 UTP5 UTP5 D7B24_008870 D7B24_008870 MAK5 MAK5 UTP13 UTP13 UTP10 UTP10 DUS3 DUS3 KRR1 KRR1 MRD1 MRD1 MDN1 MDN1 D7B24_009077 D7B24_009077 D7B24_008243 D7B24_008243 D7B24_008379 D7B24_008379 NOG2 NOG2 NOP56 NOP56 TIF6 TIF6 NOP4 NOP4 NMD3 NMD3 NOP14 NOP14 LTV1 LTV1 DBP7 DBP7 JIP5 JIP5 RMT1 RMT1 D7B24_009270 D7B24_009270 NCS2 NCS2 CBF5 CBF5 D7B24_008809 D7B24_008809 D7B24_007784 D7B24_007784 KRI1 KRI1 BFR2 BFR2 RIOK2 RIOK2 D7B24_007186 D7B24_007186 D7B24_007585 D7B24_007585 NOP16 NOP16 UTP4 UTP4 UTP7 UTP7 NOC2 NOC2 WDR36 WDR36 PPS1 PPS1 DBP3 DBP3 ECM16 ECM16 D7B24_006564 D7B24_006564 D7B24_007872 D7B24_007872 LOC1 LOC1 UTP25 UTP25 RRP36 RRP36 ABT1 ABT1 D7B24_007099 D7B24_007099 DBP8 DBP8 RMT2 RMT2 D7B24_007383 D7B24_007383 TRMT1 TRMT1 D7B24_006302 D7B24_006302 D7B24_007884 D7B24_007884 D7B24_006255 D7B24_006255 RRP12 RRP12 PUF6 PUF6 D7B24_006249 D7B24_006249 DBP10 DBP10 NOP1 NOP1 D7B24_006256 D7B24_006256 DIM1 DIM1 D7B24_006660 D7B24_006660 NIP7 NIP7 REXO4 REXO4 D7B24_007230 D7B24_007230 PUS3 PUS3 D7B24_005268 D7B24_005268 SNU13 SNU13 PUS1 PUS1 NHP2 NHP2 D7B24_005854 D7B24_005854 D7B24_004809 D7B24_004809 D7B24_005626 D7B24_005626 D7B24_005226 D7B24_005226 DDX51 DDX51 SPB4 SPB4 D7B24_005619 D7B24_005619 D7B24_006254 D7B24_006254 NOP58 NOP58 RRP3 RRP3 D7B24_005363 D7B24_005363 D7B24_005139 D7B24_005139 D7B24_004360 D7B24_004360 D7B24_003767 D7B24_003767 SOF1 SOF1 NOP10 NOP10 DBP2 DBP2 TRM61 TRM61 IMP4 IMP4 RPS6 RPS6 D7B24_002701 D7B24_002701 NOP9 NOP9 D7B24_005317 D7B24_005317 NOB1 NOB1 D7B24_004177 D7B24_004177 UTP6 UTP6 D7B24_002121 D7B24_002121 D7B24_003564 D7B24_003564 UTP20 UTP20 D7B24_001841 D7B24_001841 BMS1 BMS1 D7B24_001452 D7B24_001452 TRM6 TRM6 RRB1 RRB1 D7B24_000698 D7B24_000698 HAS1 HAS1 D7B24_006711 D7B24_006711 D7B24_005912 D7B24_005912 ESF1 ESF1 D7B24_006697 D7B24_006697 RPS9 RPS9 D7B24_005021 D7B24_005021 D7B24_003548 D7B24_003548 D7B24_009239 D7B24_009239 RPF2 RPF2 WDR3 WDR3 D7B24_003426 D7B24_003426 D7B24_000047 D7B24_000047 D7B24_005953 D7B24_005953 D7B24_006734 D7B24_006734 RRP9 RRP9 NOP12 NOP12 D7B24_005928 D7B24_005928 D7B24_000157 D7B24_000157 NSA2 NSA2 D7B24_005981 D7B24_005981 D7B24_006002 D7B24_006002 D7B24_003493 D7B24_003493 D7B24_003545 D7B24_003545 D7B24_000063 D7B24_000063 PNO1 PNO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNL3Guanine nucleotide-binding protein-like 3. (545 aa)
D7B24_004269Brix domain-containing protein. (420 aa)
ENP1SnoRNA-binding rRNA-processing protein. (483 aa)
D7B24_003411Uncharacterized protein. (303 aa)
D7B24_004397Uncharacterized protein. (269 aa)
D7B24_003851Uncharacterized protein. (604 aa)
D7B24_004072Uncharacterized protein. (373 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (862 aa)
D7B24_002894Uncharacterized protein; Belongs to the DEAD box helicase family. (717 aa)
UTP11Small subunit (SSU) processome component. (269 aa)
D7B24_002846Peptidase_M24 domain-containing protein. (410 aa)
PAK1IP1P21-activated protein kinase-interacting protein 1-like protein. (494 aa)
D7B24_002946Uncharacterized protein. (81 aa)
D7B24_003315Uncharacterized protein. (234 aa)
D7B24_002405WD_REPEATS_REGION domain-containing protein. (468 aa)
ROK1RNA-dependent ATPase rok1. (768 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (766 aa)
SDAD1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (751 aa)
NLE1Notchless protein 1. (515 aa)
D7B24_002287WD_REPEATS_REGION domain-containing protein. (905 aa)
RRP8Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (572 aa)
D7B24_003385Uncharacterized protein. (177 aa)
NOP2rRNA (Cytosine-C5-)-methyltransferase nop2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (766 aa)
D7B24_001770RTC domain-containing protein. (414 aa)
D7B24_002099Uncharacterized protein. (423 aa)
TTC27Tetratricopeptide repeat domain 27. (1040 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (658 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (247 aa)
D7B24_001246Ipi1_N domain-containing protein. (339 aa)
D7B24_001034Uncharacterized protein. (221 aa)
NOP7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (665 aa)
DUSP12Dual specificity phosphatase 12. (496 aa)
D7B24_002945Uncharacterized protein. (281 aa)
GAR1_1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (155 aa)
DNAJC21DnaJ sub C member 21. (560 aa)
RRP5rRNA bioproteinsis protein rrp5. (1809 aa)
EMG118S rRNA pseudouridine methyltransferase. (276 aa)
D7B24_000800Sas10 domain-containing protein. (668 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (399 aa)
D7B24_002053Uncharacterized protein. (383 aa)
WDR4tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (564 aa)
SGD1Suppressor of glycerol defect. (848 aa)
D7B24_000798Urb2 domain-containing protein. (1392 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (483 aa)
IMP3Small subunit (SSU) processome component. (183 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (201 aa)
KRE33RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1065 aa)
D7B24_009589Uncharacterized protein. (876 aa)
D7B24_009389CBF domain-containing protein. (1016 aa)
D7B24_009085TruB_N domain-containing protein. (505 aa)
D7B24_008935Uncharacterized protein. (1342 aa)
D7B24_009062WD_REPEATS_REGION domain-containing protein. (968 aa)
NOL6U3 small nucleolar RNA-associated protein 22. (1102 aa)
UTP5Small subunit (SSU) processome component. (433 aa)
D7B24_008870Fcf2 domain-containing protein. (197 aa)
MAK5ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (787 aa)
UTP13U3 small nucleolar RNA-associated protein 13. (906 aa)
UTP10SnoRNA-binding rRNA-processing protein utp10. (1809 aa)
DUS3tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. (742 aa)
KRR1KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (319 aa)
MRD1Multiple RNA-binding domain-containing protein 1. (866 aa)
MDN1AAA ATPase midasin. (4969 aa)
D7B24_009077Uncharacterized protein. (200 aa)
D7B24_008243Uncharacterized protein. (277 aa)
D7B24_008379Zn(2)-C6 fungal-type domain-containing protein. (432 aa)
NOG2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (609 aa)
NOP56snoRNP complex protein nop56. (510 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (246 aa)
NOP4RNA recognition motif-containing protein. (785 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (502 aa)
NOP14Nucleolar complex protein 14. (915 aa)
LTV1Protein ltv1. (428 aa)
DBP7ATP-dependent RNA helicase dbp7; Belongs to the DEAD box helicase family. (770 aa)
JIP5WD repeat-containing protein jip5. (431 aa)
RMT1Type I protein arginine N-methyltransferase Rmt1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (344 aa)
D7B24_009270UPF0020 domain-containing protein. (444 aa)
NCS2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (397 aa)
CBF5Centromere/microtubule-binding protein cbf5. (465 aa)
D7B24_008809Uncharacterized protein. (815 aa)
D7B24_007784Bms1-type G domain-containing protein. (820 aa)
KRI1KRRI-Interacting protein 1. (690 aa)
BFR2rRNA-processing protein bfr2. (594 aa)
RIOK2Serine/threonine-protein kinase RIO2. (419 aa)
D7B24_007186Uncharacterized protein. (1127 aa)
D7B24_007585Uncharacterized protein. (528 aa)
NOP16Nucleolar protein 16. (231 aa)
UTP4U3 small nucleolar RNA-associated protein. (911 aa)
UTP7Small subunit (SSU) processome component. (553 aa)
NOC2Nucleolar Complex 2 protein. (805 aa)
WDR36WD repeat-containing protein 36. (1042 aa)
PPS1Tyrosine/serine/threonine protein phosphatase pps1. (541 aa)
DBP3RNA-dependent ATPase; Belongs to the DEAD box helicase family. (595 aa)
ECM16Putative ATP-dependent RNA helicase DHR1. (1197 aa)
D7B24_006564DUF2431 domain-containing protein. (402 aa)
D7B24_007872CP-type G domain-containing protein. (643 aa)
LOC160S ribosomal subunit assembly/export protein. (202 aa)
UTP25U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (773 aa)
RRP36rRNA bioproteinsis protein rrp36. (299 aa)
ABT1Activator of basal transcription 1. (315 aa)
D7B24_007099Ribosomal_L28e domain-containing protein. (321 aa)
DBP8Putative RNA helicase; Belongs to the DEAD box helicase family. (556 aa)
RMT2Arginine N-methyltransferase 2. (467 aa)
D7B24_007383zf-LYAR domain-containing protein. (387 aa)
TRMT1tRNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (1471 aa)
D7B24_006302RIX1 domain-containing protein. (761 aa)
D7B24_007884Uncharacterized protein. (916 aa)
D7B24_006255Uncharacterized protein. (85 aa)
RRP12Pre-rRNA processing protein. (1321 aa)
PUF6Pumilio domain member 6. (708 aa)
D7B24_006249Uncharacterized protein. (1751 aa)
DBP10ATP-dependent RNA helicase DBP10. (902 aa)
NOP1Small subunit processome complex component. (325 aa)
D7B24_006256Uncharacterized protein. (363 aa)
DIM1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (370 aa)
D7B24_006660Uncharacterized protein. (678 aa)
NIP760S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (185 aa)
REXO4REX4, RNA exonuclease 4. (340 aa)
D7B24_007230Uncharacterized protein. (449 aa)
PUS3tRNA pseudouridine synthase 3. (616 aa)
D7B24_005268Uncharacterized protein; Belongs to the DEAD box helicase family. (580 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (125 aa)
PUS1tRNA pseudouridine synthase 1. (626 aa)
NHP2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (232 aa)
D7B24_005854Uncharacterized protein. (694 aa)
D7B24_004809Uncharacterized protein. (206 aa)
D7B24_005626RNase III domain-containing protein. (426 aa)
D7B24_005226Uncharacterized protein. (229 aa)
DDX51ATP-dependent RNA helicase ddx51; Belongs to the DEAD box helicase family. (775 aa)
SPB4RNA helicase. (632 aa)
D7B24_005619Uncharacterized protein. (754 aa)
D7B24_006254Uncharacterized protein. (464 aa)
NOP58Nucleolar protein 58. (655 aa)
RRP3Ribosomal RNA processing protein; Belongs to the DEAD box helicase family. (487 aa)
D7B24_005363zf-C2H2_2 domain-containing protein. (311 aa)
D7B24_005139Uncharacterized protein. (389 aa)
D7B24_004360Uncharacterized protein. (339 aa)
D7B24_003767Uncharacterized protein. (316 aa)
SOF1rRNA-processing protein sof1. (448 aa)
NOP10snoRNP complex protein. (66 aa)
DBP2ATP-dependent RNA helicase dbp2; Belongs to the DEAD box helicase family. (560 aa)
TRM61tRNA (Adenine-N(1)-)-methyltransferase catalytic subunit trm61. (514 aa)
IMP4SnoRNA-binding rRNA-processing protein imp4. (293 aa)
RPS640S ribosomal protein S6. (257 aa)
D7B24_002701Uncharacterized protein. (480 aa)
NOP9Nucleolar protein 9. (748 aa)
D7B24_005317Uncharacterized protein. (231 aa)
NOB1Nin1 binding protein. (472 aa)
D7B24_004177Brix domain-containing protein. (462 aa)
UTP6U3 snoRNP protein. (416 aa)
D7B24_002121RRM domain-containing protein. (386 aa)
D7B24_003564SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (936 aa)
UTP20U3 snoRNP protein. (2640 aa)
D7B24_001841Uncharacterized protein. (581 aa)
BMS1Glycoside hydrolase 2 (Mannanase, beta-galactosidase). (1159 aa)
D7B24_001452Uncharacterized protein. (1028 aa)
TRM6tRNA (Adenine(58)-N(1))-methyltransferase non-catalytic subunit trm6. (625 aa)
RRB1Ribosome biosynthesis protein rrb1. (492 aa)
D7B24_000698WD_REPEATS_REGION domain-containing protein. (500 aa)
HAS1RNA helicase. (706 aa)
D7B24_006711Cytochrome b5 heme-binding domain-containing protein. (754 aa)
D7B24_005912CBF domain-containing protein. (546 aa)
ESF1Pre-rRNA-processing protein esf1. (699 aa)
D7B24_006697zf-C2H2_2 domain-containing protein. (372 aa)
RPS940S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (191 aa)
D7B24_005021RRM domain-containing protein. (316 aa)
D7B24_003548C2H2-type domain-containing protein. (560 aa)
D7B24_009239Uncharacterized protein. (475 aa)
RPF2rRNA-binding ribosome biosynthesis protein rpf2. (317 aa)
WDR3Dip2/Utp12 protein. (1050 aa)
D7B24_003426Uncharacterized protein. (940 aa)
D7B24_000047PPM-type phosphatase domain-containing protein. (786 aa)
D7B24_005953rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (118 aa)
D7B24_006734ANK_REP_REGION domain-containing protein. (186 aa)
RRP9Pre-rRNA processing protein. (606 aa)
NOP12Nucleolar protein 12. (550 aa)
D7B24_005928Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (196 aa)
D7B24_000157Uncharacterized protein. (710 aa)
NSA2Ribosome bioproteinsis protein. (284 aa)
D7B24_005981Uncharacterized protein. (402 aa)
D7B24_006002WD_REPEATS_REGION domain-containing protein. (598 aa)
D7B24_003493WD_REPEATS_REGION domain-containing protein. (634 aa)
D7B24_003545SRP40_C domain-containing protein. (473 aa)
D7B24_000063WD_REPEATS_REGION domain-containing protein. (535 aa)
PNO1Pre-rRNA-processing protein pno1. (257 aa)
Your Current Organism:
Verticillium nonalfalfae
NCBI taxonomy Id: 1051616
Other names: CBS 130339, NRRL 54791, PD592, UC 1953898, V. nonalfalfae, Verticillium sp. PI-2011d
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