STRINGSTRING
MCM3 MCM3 MCM5 MCM5 RAD51 RAD51 D7B24_000965 D7B24_000965 RAD54 RAD54 SMC6 SMC6 D7B24_001708 D7B24_001708 D7B24_003689 D7B24_003689 SCC2 SCC2 D7B24_002671 D7B24_002671 SMC5 SMC5 D7B24_004517 D7B24_004517 D7B24_007656 D7B24_007656 D7B24_007943 D7B24_007943 UBC2 UBC2 RFA1 RFA1 FAN1 FAN1 MCM7 MCM7 D7B24_007482 D7B24_007482 REV3L REV3L D7B24_003466 D7B24_003466 MRE11 MRE11 D7B24_003634 D7B24_003634 RAD52 RAD52 D7B24_004435 D7B24_004435 D7B24_004700 D7B24_004700 D7B24_005339 D7B24_005339 D7B24_005246 D7B24_005246 MCM2 MCM2 D7B24_006999 D7B24_006999 MCM4 MCM4 D7B24_007211 D7B24_007211 D7B24_007655 D7B24_007655 D7B24_007076 D7B24_007076 MCD1 MCD1 MCM6 MCM6 RFA2 RFA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM3DNA helicase; Belongs to the MCM family. (884 aa)
MCM5DNA helicase; Belongs to the MCM family. (721 aa)
RAD51DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (355 aa)
D7B24_000965zf-RING-like domain-containing protein. (345 aa)
RAD54DNA-dependent ATPase protein rad54. (859 aa)
SMC6Structural maintenance of chromosomes protein 6. (1165 aa)
D7B24_001708Uncharacterized protein. (92 aa)
D7B24_003689MAGE domain-containing protein. (338 aa)
SCC2Sister chromatid cohesion protein. (1868 aa)
D7B24_002671Deacetylase sirtuin-type domain-containing protein. (729 aa)
SMC5Structural maintenance of chromosomes protein 5. (1117 aa)
D7B24_004517Uncharacterized protein. (393 aa)
D7B24_007656Uncharacterized protein. (427 aa)
D7B24_007943Serine/threonine-protein phosphatase. (422 aa)
UBC2Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
RFA1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (617 aa)
FAN1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (843 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (838 aa)
D7B24_007482WD_REPEATS_REGION domain-containing protein. (1032 aa)
REV3LDNA polymerase. (1686 aa)
D7B24_003466SP-RING-type domain-containing protein. (402 aa)
MRE11Meiotic recombination; Belongs to the MRE11/RAD32 family. (701 aa)
D7B24_003634XPGI domain-containing protein. (464 aa)
RAD52DNA repair protein rad52. (524 aa)
D7B24_004435RECA_2 domain-containing protein. (459 aa)
D7B24_004700Uncharacterized protein. (858 aa)
D7B24_005339Protein kinase domain-containing protein. (473 aa)
D7B24_005246Deacetylase sirtuin-type domain-containing protein. (428 aa)
MCM2DNA helicase; Belongs to the MCM family. (914 aa)
D7B24_006999ERCC4 domain-containing protein. (951 aa)
MCM4DNA helicase; Belongs to the MCM family. (1028 aa)
D7B24_007211Uncharacterized protein. (443 aa)
D7B24_007655Uncharacterized protein. (924 aa)
D7B24_007076Checkpoint protein; Belongs to the HUS1 family. (339 aa)
MCD1Sister chromatid cohesion protein 1. (651 aa)
MCM6DNA helicase; Belongs to the MCM family. (953 aa)
RFA2Replication factor A protein 2. (290 aa)
Your Current Organism:
Verticillium nonalfalfae
NCBI taxonomy Id: 1051616
Other names: CBS 130339, NRRL 54791, PD592, UC 1953898, V. nonalfalfae, Verticillium sp. PI-2011d
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