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| TEL1 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3104 aa) | ||||
| D7B24_009100 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3836 aa) | ||||
| TOR1 | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2442 aa) | ||||
| MEC1_1 | Serine/threonine-protein kinase M1; Belongs to the PI3/PI4-kinase family. (2248 aa) | ||||