(16 nodes) Iron ion transmembrane transport network (Vibrio tubiashii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AIW13493.1	Iron transporter FeoB; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (758 aa)
	AIW16924.1	Aerobactin siderophore receptor iutA; Derived by automated computational analysis using gene prediction method: Protein Homology. (718 aa)
	AIW16921.1	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
	AIW16838.1	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (716 aa)
	AIW16327.1	TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (710 aa)
	AIW12943.1	Iron transporter FeoB; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (833 aa)
	AIW16190.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
	AIW16135.1	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (746 aa)
	AIW16129.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
	AIW16009.1	Cobalt-zinc-cadmium resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
	AIW15972.1	Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
	fieF	Ferrous iron transporter; Member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (302 aa)
	AIW14194.1	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (696 aa)
	AIW14189.1	Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (205 aa)
	ccmA	Cytochrome C biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (206 aa)
	AIW13069.1	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (343 aa)

Your Current Organism:

Vibrio tubiashii

NCBI taxonomy Id: 1051646
Other names: V. tubiashii ATCC 19109, Vibrio tubiashii ATCC 19109, Vibrio tubiashii LMG 10396, Vibrio tubiashii NBRC 15644, Vibrio tubiashii str. ATCC 19109, Vibrio tubiashii strain ATCC 19109

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIW14189.1	AIW14194.1	IX91_08260	IX91_08285	Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.866
AIW14189.1	AIW16135.1	IX91_08260	IX91_18735	Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.874
AIW14189.1	AIW16327.1	IX91_08260	IX91_19740	Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.	TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.862
AIW14189.1	AIW16838.1	IX91_08260	IX91_22420	Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.703
AIW14189.1	AIW16924.1	IX91_08260	IX91_22865	Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.	Aerobactin siderophore receptor iutA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.822
AIW14194.1	AIW14189.1	IX91_08285	IX91_08260	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.	0.866
AIW14194.1	AIW15972.1	IX91_08285	IX91_17890	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.724
AIW14194.1	AIW16135.1	IX91_08285	IX91_18735	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.462
AIW14194.1	AIW16327.1	IX91_08285	IX91_19740	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.687
AIW14194.1	AIW16924.1	IX91_08285	IX91_22865	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aerobactin siderophore receptor iutA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.653
AIW15972.1	AIW14194.1	IX91_17890	IX91_08285	Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.724
AIW15972.1	AIW16135.1	IX91_17890	IX91_18735	Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.889
AIW15972.1	AIW16327.1	IX91_17890	IX91_19740	Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.	TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.891
AIW15972.1	AIW16838.1	IX91_17890	IX91_22420	Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.731
AIW15972.1	AIW16924.1	IX91_17890	IX91_22865	Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aerobactin siderophore receptor iutA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.795
AIW16129.1	AIW16135.1	IX91_18705	IX91_18735	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.811
AIW16129.1	AIW16327.1	IX91_18705	IX91_19740	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.459
AIW16129.1	AIW16838.1	IX91_18705	IX91_22420	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.619
AIW16129.1	AIW16921.1	IX91_18705	IX91_22850	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.920
AIW16129.1	AIW16924.1	IX91_18705	IX91_22865	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aerobactin siderophore receptor iutA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.587

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